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High-throughput Oligopaint screen identifies druggable 3D genome regulators.
Park DS, Nguyen SC, Isenhart R, Shah PP, Kim W, Barnett RJ, Chandra A, Luppino JM, Harke J, Wai M, Walsh PJ, Abdill RJ, Yang R, Lan Y, Yoon S, Yunker R, Kanemaki MT, Vahedi G, Phillips-Cremins JE, Jain R, Joyce EF. Park DS, et al. Among authors: shah pp. Nature. 2023 Aug;620(7972):209-217. doi: 10.1038/s41586-023-06340-w. Epub 2023 Jul 12. Nature. 2023. PMID: 37438531
BRD4 orchestrates genome folding to promote neural crest differentiation.
Linares-Saldana R, Kim W, Bolar NA, Zhang H, Koch-Bojalad BA, Yoon S, Shah PP, Karnay A, Park DS, Luppino JM, Nguyen SC, Padmanabhan A, Smith CL, Poleshko A, Wang Q, Li L, Srivastava D, Vahedi G, Eom GH, Blobel GA, Joyce EF, Jain R. Linares-Saldana R, et al. Among authors: shah pp. Nat Genet. 2021 Oct;53(10):1480-1492. doi: 10.1038/s41588-021-00934-8. Epub 2021 Oct 5. Nat Genet. 2021. PMID: 34611363 Free PMC article.
Publisher Correction: BRD4 orchestrates genome folding to promote neural crest differentiation.
Linares-Saldana R, Kim W, Bolar NA, Zhang H, Koch-Bojalad BA, Yoon S, Shah PP, Karnay A, Park DS, Luppino JM, Nguyen SC, Padmanabhan A, Smith CL, Poleshko A, Wang Q, Li L, Srivastava D, Vahedi G, Eom GH, Blobel GA, Joyce EF, Jain R. Linares-Saldana R, et al. Among authors: shah pp. Nat Genet. 2021 Dec;53(12):1723. doi: 10.1038/s41588-021-00980-2. Nat Genet. 2021. PMID: 34725478 No abstract available.
BRD4 (Bromodomain-Containing Protein 4) Interacts with GATA4 (GATA Binding Protein 4) to Govern Mitochondrial Homeostasis in Adult Cardiomyocytes.
Padmanabhan A, Alexanian M, Linares-Saldana R, González-Terán B, Andreoletti G, Huang Y, Connolly AJ, Kim W, Hsu A, Duan Q, Winchester SAB, Felix F, Perez-Bermejo JA, Wang Q, Li L, Shah PP, Haldar SM, Jain R, Srivastava D. Padmanabhan A, et al. Among authors: shah pp. Circulation. 2020 Dec 15;142(24):2338-2355. doi: 10.1161/CIRCULATIONAHA.120.047753. Epub 2020 Oct 23. Circulation. 2020. PMID: 33094644 Free PMC article.
199 results