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mRNA vaccine against malaria tailored for liver-resident memory T cells.
Ganley M, Holz LE, Minnell JJ, de Menezes MN, Burn OK, Poa KCY, Draper SL, English K, Chan STS, Anderson RJ, Compton BJ, Marshall AJ, Cozijnsen A, Chua YC, Ge Z, Farrand KJ, Mamum JC, Xu C, Cockburn IA, Yui K, Bertolino P, Gras S, Le Nours J, Rossjohn J, Fernandez-Ruiz D, McFadden GI, Ackerley DF, Painter GF, Hermans IF, Heath WR. Ganley M, et al. Among authors: painter gf. Nat Immunol. 2023 Sep;24(9):1487-1498. doi: 10.1038/s41590-023-01562-6. Epub 2023 Jul 20. Nat Immunol. 2023. PMID: 37474653
Glycolipid-peptide vaccination induces liver-resident memory CD8+ T cells that protect against rodent malaria.
Holz LE, Chua YC, de Menezes MN, Anderson RJ, Draper SL, Compton BJ, Chan STS, Mathew J, Li J, Kedzierski L, Wang Z, Beattie L, Enders MH, Ghilas S, May R, Steiner TM, Lange J, Fernandez-Ruiz D, Valencia-Hernandez AM, Osmond TL, Farrand KJ, Seneviratna R, Almeida CF, Tullett KM, Bertolino P, Bowen DG, Cozijnsen A, Mollard V, McFadden GI, Caminschi I, Lahoud MH, Kedzierska K, Turner SJ, Godfrey DI, Hermans IF, Painter GF, Heath WR. Holz LE, et al. Among authors: painter gf. Sci Immunol. 2020 Jun 26;5(48):eaaz8035. doi: 10.1126/sciimmunol.aaz8035. Sci Immunol. 2020. PMID: 32591409
6″-Modifed α-GalCer-peptide conjugate vaccine candidates protect against liver-stage malaria.
Meijlink MA, Chua YC, Chan STS, Anderson RJ, Rosenberg MW, Cozijnsen A, Mollard V, McFadden GI, Draper SL, Holz LE, Hermans IF, Heath WR, Painter GF, Compton BJ. Meijlink MA, et al. Among authors: painter gf. RSC Chem Biol. 2022 Mar 2;3(5):551-560. doi: 10.1039/d1cb00251a. eCollection 2022 May 11. RSC Chem Biol. 2022. PMID: 35656478 Free PMC article.
A self-adjuvanting vaccine induces cytotoxic T lymphocytes that suppress allergy.
Anderson RJ, Tang CW, Daniels NJ, Compton BJ, Hayman CM, Johnston KA, Knight DA, Gasser O, Poyntz HC, Ferguson PM, Larsen DS, Ronchese F, Painter GF, Hermans IF. Anderson RJ, et al. Among authors: painter gf. Nat Chem Biol. 2014 Nov;10(11):943-9. doi: 10.1038/nchembio.1640. Epub 2014 Oct 5. Nat Chem Biol. 2014. PMID: 25282504
Augmenting Influenza-Specific T Cell Memory Generation with a Natural Killer T Cell-Dependent Glycolipid-Peptide Vaccine.
Anderson RJ, Li J, Kedzierski L, Compton BJ, Hayman CM, Osmond TL, Tang CW, Farrand KJ, Koay HF, Almeida CFDSSE, Holz LR, Williams GM, Brimble MA, Wang Z, Koutsakos M, Kedzierska K, Godfrey DI, Hermans IF, Turner SJ, Painter GF. Anderson RJ, et al. Among authors: painter gf. ACS Chem Biol. 2017 Nov 17;12(11):2898-2905. doi: 10.1021/acschembio.7b00845. Epub 2017 Oct 27. ACS Chem Biol. 2017. PMID: 29043774
Using agonists for iNKT cells in cancer therapy.
Painter GF, Burn OK, Hermans IF. Painter GF, et al. Mol Immunol. 2021 Feb;130:1-6. doi: 10.1016/j.molimm.2020.12.010. Epub 2020 Dec 16. Mol Immunol. 2021. PMID: 33340930
Glycolipid-peptide conjugate vaccines elicit CD8+ T-cell responses and prevent breast cancer metastasis.
Burn OK, Farrand K, Pritchard T, Draper S, Tang CW, Mooney AH, Schmidt AJ, Yang SH, Williams GM, Brimble MA, Kandasamy M, Marshall AJ, Clarke K, Painter GF, Hermans IF, Weinkove R. Burn OK, et al. Among authors: painter gf. Clin Transl Immunology. 2022 Jul 3;11(7):e1401. doi: 10.1002/cti2.1401. eCollection 2022. Clin Transl Immunology. 2022. PMID: 35795321 Free PMC article.
89 results