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Acetylation of the NS3 helicase by KAT5γ is essential for flavivirus replication.
Serman T, Chiang C, Liu G, Sayyad Z, Pandey S, Volcic M, Lee H, Muppala S, Acharya D, Goins C, Stauffer SR, Sparrer KMJ, Gack MU. Serman T, et al. Among authors: sparrer kmj. Cell Host Microbe. 2023 Aug 9;31(8):1317-1330.e10. doi: 10.1016/j.chom.2023.06.013. Epub 2023 Jul 20. Cell Host Microbe. 2023. PMID: 37478852
Intracellular detection of viral nucleic acids.
Sparrer KM, Gack MU. Sparrer KM, et al. Curr Opin Microbiol. 2015 Aug;26:1-9. doi: 10.1016/j.mib.2015.03.001. Epub 2015 Mar 18. Curr Opin Microbiol. 2015. PMID: 25795286 Free PMC article. Review.
Mechanism of TRIM25 Catalytic Activation in the Antiviral RIG-I Pathway.
Sanchez JG, Chiang JJ, Sparrer KMJ, Alam SL, Chi M, Roganowicz MD, Sankaran B, Gack MU, Pornillos O. Sanchez JG, et al. Among authors: sparrer kmj. Cell Rep. 2016 Aug 2;16(5):1315-1325. doi: 10.1016/j.celrep.2016.06.070. Epub 2016 Jul 14. Cell Rep. 2016. PMID: 27425606 Free PMC article.
TRIM23 mediates virus-induced autophagy via activation of TBK1.
Sparrer KMJ, Gableske S, Zurenski MA, Parker ZM, Full F, Baumgart GJ, Kato J, Pacheco-Rodriguez G, Liang C, Pornillos O, Moss J, Vaughan M, Gack MU. Sparrer KMJ, et al. Nat Microbiol. 2017 Nov;2(11):1543-1557. doi: 10.1038/s41564-017-0017-2. Epub 2017 Sep 4. Nat Microbiol. 2017. PMID: 28871090 Free PMC article.
TRIM proteins: New players in virus-induced autophagy.
Sparrer KMJ, Gack MU. Sparrer KMJ, et al. PLoS Pathog. 2018 Feb 1;14(2):e1006787. doi: 10.1371/journal.ppat.1006787. eCollection 2018 Feb. PLoS Pathog. 2018. PMID: 29389992 Free PMC article. No abstract available.
TRIM Proteins and Their Roles in Antiviral Host Defenses.
van Gent M, Sparrer KMJ, Gack MU. van Gent M, et al. Among authors: sparrer kmj. Annu Rev Virol. 2018 Sep 29;5(1):385-405. doi: 10.1146/annurev-virology-092917-043323. Epub 2018 Jun 27. Annu Rev Virol. 2018. PMID: 29949725 Free PMC article. Review.
TRIM25 Binds RNA to Modulate Cellular Anti-viral Defense.
Sanchez JG, Sparrer KMJ, Chiang C, Reis RA, Chiang JJ, Zurenski MA, Wan Y, Gack MU, Pornillos O. Sanchez JG, et al. Among authors: sparrer kmj. J Mol Biol. 2018 Dec 7;430(24):5280-5293. doi: 10.1016/j.jmb.2018.10.003. Epub 2018 Oct 17. J Mol Biol. 2018. PMID: 30342007 Free PMC article.
Vpu modulates DNA repair to suppress innate sensing and hyper-integration of HIV-1.
Volcic M, Sparrer KMJ, Koepke L, Hotter D, Sauter D, Stürzel CM, Scherer M, Stamminger T, Hofmann TG, Arhel NJ, Wiesmüller L, Kirchhoff F. Volcic M, et al. Among authors: sparrer kmj. Nat Microbiol. 2020 Oct;5(10):1247-1261. doi: 10.1038/s41564-020-0753-6. Epub 2020 Jul 20. Nat Microbiol. 2020. PMID: 32690953
66 results