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An E-cadherin-actin clutch translates the mechanical force of cortical flow for cell-cell contact to inhibit epithelial cell locomotion.
Noordstra I, Hermoso MD, Schimmel L, Bonfim-Melo A, Currin-Ross D, Duong CN, Kalappurakkal JM, Morris RG, Vestweber D, Mayor S, Gordon E, Roca-Cusachs P, Yap AS. Noordstra I, et al. Among authors: roca cusachs p. Dev Cell. 2023 Sep 25;58(18):1748-1763.e6. doi: 10.1016/j.devcel.2023.06.011. Epub 2023 Jul 21. Dev Cell. 2023. PMID: 37480844
Physical principles of membrane remodelling during cell mechanoadaptation.
Kosmalska AJ, Casares L, Elosegui-Artola A, Thottacherry JJ, Moreno-Vicente R, González-Tarragó V, Del Pozo MÁ, Mayor S, Arroyo M, Navajas D, Trepat X, Gauthier NC, Roca-Cusachs P. Kosmalska AJ, et al. Nat Commun. 2015 Jun 15;6:7292. doi: 10.1038/ncomms8292. Nat Commun. 2015. PMID: 26073653 Free PMC article.
Control of Mechanotransduction by Molecular Clutch Dynamics.
Elosegui-Artola A, Trepat X, Roca-Cusachs P. Elosegui-Artola A, et al. Trends Cell Biol. 2018 May;28(5):356-367. doi: 10.1016/j.tcb.2018.01.008. Epub 2018 Feb 26. Trends Cell Biol. 2018. PMID: 29496292 Review.
Mechanochemical feedback control of dynamin independent endocytosis modulates membrane tension in adherent cells.
Thottacherry JJ, Kosmalska AJ, Kumar A, Vishen AS, Elosegui-Artola A, Pradhan S, Sharma S, Singh PP, Guadamillas MC, Chaudhary N, Vishwakarma R, Trepat X, Del Pozo MA, Parton RG, Rao M, Pullarkat P, Roca-Cusachs P, Mayor S. Thottacherry JJ, et al. Nat Commun. 2018 Oct 11;9(1):4217. doi: 10.1038/s41467-018-06738-5. Nat Commun. 2018. PMID: 30310066 Free PMC article.
Mechanical force application to the nucleus regulates nucleocytoplasmic transport.
Andreu I, Granero-Moya I, Chahare NR, Clein K, Molina-Jordán M, Beedle AEM, Elosegui-Artola A, Abenza JF, Rossetti L, Trepat X, Raveh B, Roca-Cusachs P. Andreu I, et al. Nat Cell Biol. 2022 Jun;24(6):896-905. doi: 10.1038/s41556-022-00927-7. Epub 2022 Jun 9. Nat Cell Biol. 2022. PMID: 35681009 Free PMC article.
Competition for endothelial cell polarity drives vascular morphogenesis in the mouse retina.
Barbacena P, Dominguez-Cejudo M, Fonseca CG, Gómez-González M, Faure LM, Zarkada G, Pena A, Pezzarossa A, Ramalho D, Giarratano Y, Ouarné M, Barata D, Fortunato IC, Misikova LH, Mauldin I, Carvalho Y, Trepat X, Roca-Cusachs P, Eichmann A, Bernabeu MO, Franco CA. Barbacena P, et al. Dev Cell. 2022 Oct 10;57(19):2321-2333.e9. doi: 10.1016/j.devcel.2022.09.002. Dev Cell. 2022. PMID: 36220082 Free PMC article.
71 results