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Aster-dependent non-vesicular transport facilitates dietary cholesterol uptake.
Ferrari A, Whang E, Xiao X, Kennelly JP, Romartinez-Alonso B, Mack JJ, Weston T, Chen K, Kim Y, Tol MJ, Bideyan L, Nguyen A, Gao Y, Cui L, Bedard AH, Sandhu J, Lee SD, Fairall L, Williams KJ, Song W, Munguia P, Russell RA, Martin MG, Jung ME, Jiang H, Schwabe JWR, Young SG, Tontonoz P. Ferrari A, et al. Among authors: kennelly jp. bioRxiv [Preprint]. 2023 Jul 10:2023.07.07.548168. doi: 10.1101/2023.07.07.548168. bioRxiv. 2023. PMID: 37503112 Free PMC article. Updated. Preprint.
Low MBOAT7 expression, a genetic risk for MASH, promotes a pro-fibrotic pathway involving hepatocyte TAZ upregulation.
Moore MP, Wang X, Kennelly JP, Shi H, Ishino Y, Kano K, Aoki J, Cherubini A, Ronzoni L, Guo X, Chalasani NP, Khalid S, Saleheen D, Mitsche MA, Rotter JI, Yates KP, Valenti L, Kono N, Tontonoz P, Tabas I. Moore MP, et al. Among authors: kennelly jp. Hepatology. 2024 May 22. doi: 10.1097/HEP.0000000000000933. Online ahead of print. Hepatology. 2024. PMID: 38776184
Aster-dependent nonvesicular transport facilitates dietary cholesterol uptake.
Ferrari A, Whang E, Xiao X, Kennelly JP, Romartinez-Alonso B, Mack JJ, Weston T, Chen K, Kim Y, Tol MJ, Bideyan L, Nguyen A, Gao Y, Cui L, Bedard AH, Sandhu J, Lee SD, Fairall L, Williams KJ, Song W, Munguia P, Russell RA, Martin MG, Jung ME, Jiang H, Schwabe JWR, Young SG, Tontonoz P. Ferrari A, et al. Among authors: kennelly jp. Science. 2023 Nov 10;382(6671):eadf0966. doi: 10.1126/science.adf0966. Epub 2023 Nov 10. Science. 2023. PMID: 37943936 Free PMC article.
Hepatic nonvesicular cholesterol transport is critical for systemic lipid homeostasis.
Xiao X, Kennelly JP, Ferrari A, Clifford BL, Whang E, Gao Y, Qian K, Sandhu J, Jarrett KE, Brearley-Sholto MC, Nguyen A, Nagari RT, Lee MS, Zhang S, Weston TA, Young SG, Bensinger SJ, Villanueva CJ, de Aguiar Vallim TQ, Tontonoz P. Xiao X, et al. Among authors: kennelly jp. Nat Metab. 2023 Jan;5(1):165-181. doi: 10.1038/s42255-022-00722-6. Epub 2023 Jan 16. Nat Metab. 2023. PMID: 36646756 Free PMC article.
Sphingosine kinases regulate ER contacts with late endocytic organelles and cholesterol trafficking.
Palladino END, Bernas T, Green CD, Weigel C, Singh SK, Senkal CE, Martello A, Kennelly JP, Bieberich E, Tontonoz P, Ford DA, Milstien S, Eden ER, Spiegel S. Palladino END, et al. Among authors: kennelly jp. Proc Natl Acad Sci U S A. 2022 Sep 27;119(39):e2204396119. doi: 10.1073/pnas.2204396119. Epub 2022 Sep 19. Proc Natl Acad Sci U S A. 2022. PMID: 36122218 Free PMC article.
22 results