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Detection of Age-Related Somatic Alterations in Canine Blood Using Next-Generation Sequencing-Based Liquid Biopsy: An Analysis of over 4800 Dogs.
Vet Sci. 2023 Jul 11;10(7):455. doi: 10.3390/vetsci10070455.
Vet Sci. 2023.
PMID: 37505860
Free PMC article.
Cancer detection in clinical practice and using blood-based liquid biopsy: A retrospective audit of over 350 dogs.
Flory A, McLennan L, Peet B, Kroll M, Stuart D, Brown D, Stuebner K, Phillips B, Coomber BL, Woods JP, Miller M, Tripp CD, Wolf-Ringwall A, Kruglyak KM, McCleary-Wheeler AL, Phelps-Dunn A, Wong LK, Warren CD, Brandstetter G, Rosentel MC, DiMarzio LR, O'Kell AL, Cohen TA, Grosu DS, Chibuk J, Tsui DWY, Chorny I, Rafalko JM.
Flory A, et al.
J Vet Intern Med. 2023 Jan;37(1):258-267. doi: 10.1111/jvim.16616. Epub 2023 Jan 20.
J Vet Intern Med. 2023.
PMID: 36661398
Free PMC article.
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Age at cancer diagnosis by breed, weight, sex, and cancer type in a cohort of more than 3,000 dogs: Determining the optimal age to initiate cancer screening in canine patients.
Rafalko JM, Kruglyak KM, McCleary-Wheeler AL, Goyal V, Phelps-Dunn A, Wong LK, Warren CD, Brandstetter G, Rosentel MC, DiMarzio L, McLennan LM, O'Kell AL, Cohen TA, Grosu DS, Chibuk J, Tsui DWY, Chorny I, Flory A.
Rafalko JM, et al. Among authors: mclennan lm.
PLoS One. 2023 Feb 1;18(2):e0280795. doi: 10.1371/journal.pone.0280795. eCollection 2023.
PLoS One. 2023.
PMID: 36724177
Free PMC article.
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Next-generation sequencing-based liquid biopsy may be used for detection of residual disease and cancer recurrence monitoring in dogs.
McCleary-Wheeler AL, Fiaux PC, Flesner BK, Ruiz-Perez CA, McLennan LM, Tynan JA, Hicks SC, Rafalko JM, Grosu DS, Chibuk J, O'Kell AL, Cohen TA, Chorny I, Tsui DWY, Kruglyak KM, Flory A.
McCleary-Wheeler AL, et al. Among authors: mclennan lm.
Am J Vet Res. 2023 Dec 28:1-8. doi: 10.2460/ajvr.23.07.0163. Online ahead of print.
Am J Vet Res. 2023.
PMID: 38150822
Free article.
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Clinical validation of a blood-based liquid biopsy test integrating cell-free DNA quantification and next-generation sequencing for cancer screening in dogs.
Flory A, Ruiz-Perez CA, Clavere-Graciette AG, Rafalko JM, O'Kell AL, Flesner BK, McLennan LM, Hicks SC, Nakashe P, Phelps-Dunn A, DiMarzio LR, Warren CD, Cohen TA, Chibuk J, Chorny I, Grosu DS, Tsui DWY, Tynan JA, Kruglyak KM.
Flory A, et al. Among authors: mclennan lm.
J Am Vet Med Assoc. 2024 Feb 7;262(5):665-673. doi: 10.2460/javma.23.10.0564. Print 2024 May 1.
J Am Vet Med Assoc. 2024.
PMID: 38324993
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Clinical validation of a next-generation sequencing-based multi-cancer early detection "liquid biopsy" blood test in over 1,000 dogs using an independent testing set: The CANcer Detection in Dogs (CANDiD) study.
Flory A, Kruglyak KM, Tynan JA, McLennan LM, Rafalko JM, Fiaux PC, Hernandez GE, Marass F, Nakashe P, Ruiz-Perez CA, Fath DM, Jennings T, Motalli-Pepio R, Wotrang K, McCleary-Wheeler AL, Lana S, Phillips B, Flesner BK, Leibman NF, LaDue T, Tripp CD, Coomber BL, Woods JP, Miller M, Aiken SW, Wolf-Ringwall A, Borgatti A, Kraska K, Thomson CB, Kosanovich Cahalane A, Murray RL, Kisseberth WC, Camps-Palau MA, Floch F, Beaudu-Lange C, Klajer-Peres A, Keravel O, Fribourg-Blanc LA, Mazetier PC, Marco A, McLeod MB, Portillo E, Clark TS, Judd S, Feinberg CK, Benitez M, Runyan C, Hackett L, Lafey S, Richardson D, Vineyard S, Tefend Campbell M, Dharajiya N, Jensen TJ, van den Boom D, Diaz LA Jr, Grosu DS, Polk A, Marsal K, Hicks SC, Lytle KM, Holtvoigt L, Chibuk J, Chorny I, Tsui DWY.
Flory A, et al. Among authors: mclennan lm.
PLoS One. 2022 Apr 26;17(4):e0266623. doi: 10.1371/journal.pone.0266623. eCollection 2022.
PLoS One. 2022.
PMID: 35471999
Free PMC article.
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