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Direct cysteine sulfenylation drives activation of the Src kinase.
Heppner DE, Dustin CM, Liao C, Hristova M, Veith C, Little AC, Ahlers BA, White SL, Deng B, Lam YW, Li J, van der Vliet A. Heppner DE, et al. Among authors: lam yw. Nat Commun. 2018 Oct 30;9(1):4522. doi: 10.1038/s41467-018-06790-1. Nat Commun. 2018. PMID: 30375386 Free PMC article.
Dysregulation of the glutaredoxin/S-glutathionylation redox axis in lung diseases.
Chia SB, Elko EA, Aboushousha R, Manuel AM, van de Wetering C, Druso JE, van der Velden J, Seward DJ, Anathy V, Irvin CG, Lam YW, van der Vliet A, Janssen-Heininger YMW. Chia SB, et al. Among authors: lam yw. Am J Physiol Cell Physiol. 2020 Feb 1;318(2):C304-C327. doi: 10.1152/ajpcell.00410.2019. Epub 2019 Nov 6. Am J Physiol Cell Physiol. 2020. PMID: 31693398 Free PMC article.
Glutathionylation chemistry promotes interleukin-1 beta-mediated glycolytic reprogramming and pro-inflammatory signaling in lung epithelial cells.
Aboushousha R, Elko E, Chia SB, Manuel AM, van de Wetering C, van der Velden J, MacPherson M, Erickson C, Reisz JA, D'Alessandro A, Wouters EFM, Reynaert NL, Lam YW, Anathy V, van der Vliet A, Seward DJ, Janssen-Heininger YMW. Aboushousha R, et al. Among authors: lam yw. FASEB J. 2021 May;35(5):e21525. doi: 10.1096/fj.202002687RR. FASEB J. 2021. PMID: 33817836 Free PMC article.
Inhibition of PDIA3 in club cells attenuates osteopontin production and lung fibrosis.
Kumar A, Elko E, Bruno SR, Mark ZF, Chamberlain N, Mihavics BK, Chandrasekaran R, Walzer J, Ruban M, Gold C, Lam YW, Ghandikota S, Jegga AG, Gomez JL, Janssen-Heininger YM, Anathy V. Kumar A, et al. Among authors: lam yw. Thorax. 2022 Jul;77(7):669-678. doi: 10.1136/thoraxjnl-2021-216882. Epub 2021 Aug 16. Thorax. 2022. PMID: 34400514 Free PMC article.
Mitoquinone mesylate attenuates pathological features of lean and obese allergic asthma in mice.
Chandrasekaran R, Bruno SR, Mark ZF, Walzer J, Caffry S, Gold C, Kumar A, Chamberlain N, Butzirus IM, Morris CR, Daphtary N, Aliyeva M, Lam YW, van der Vliet A, Janssen-Heininger Y, Poynter ME, Dixon AE, Anathy V. Chandrasekaran R, et al. Among authors: lam yw. Am J Physiol Lung Cell Mol Physiol. 2023 Feb 1;324(2):L141-L153. doi: 10.1152/ajplung.00249.2022. Epub 2022 Dec 13. Am J Physiol Lung Cell Mol Physiol. 2023. PMID: 36511516 Free PMC article.
TGF-β1-induced deposition of provisional extracellular matrix by tracheal basal cells promotes epithelial-to-mesenchymal transition in a c-Jun NH2-terminal kinase-1-dependent manner.
van der Velden JL, Wagner DE, Lahue KG, Abdalla ST, Lam YW, Weiss DJ, Janssen-Heininger YMW. van der Velden JL, et al. Among authors: lam yw. Am J Physiol Lung Cell Mol Physiol. 2018 Jun 1;314(6):L984-L997. doi: 10.1152/ajplung.00053.2017. Epub 2018 Feb 22. Am J Physiol Lung Cell Mol Physiol. 2018. PMID: 29469614 Free PMC article.
229 results