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Structural and functional fine mapping of cysteines in mammalian glutaredoxin reveal their differential oxidation susceptibility.
Corteselli EM, Sharafi M, Hondal R, MacPherson M, White S, Lam YW, Gold C, Manuel AM, van der Vliet A, Schneebeli ST, Anathy V, Li J, Janssen-Heininger YMW. Corteselli EM, et al. Among authors: macpherson m. Nat Commun. 2023 Jul 28;14(1):4550. doi: 10.1038/s41467-023-39664-2. Nat Commun. 2023. PMID: 37507364 Free PMC article.
Exosomes from asbestos-exposed cells modulate gene expression in mesothelial cells.
Munson P, Lam YW, Dragon J, MacPherson M, Shukla A. Munson P, et al. Among authors: macpherson m. FASEB J. 2018 Aug;32(8):4328-4342. doi: 10.1096/fj.201701291RR. Epub 2018 Mar 19. FASEB J. 2018. PMID: 29553831 Free PMC article.
This is the first report to indicate that asbestos-exposed cells secrete exosomes with differentially abundant proteins and that those exosomes have a gene-altering effect on mesothelial cells.-Munson, P., Lam, Y.-W., Dragon, J. MacPherson, M., Shukla, A. Exosomes f …
This is the first report to indicate that asbestos-exposed cells secrete exosomes with differentially abundant proteins and that those exoso …
Pyruvate Kinase M2 Promotes Expression of Proinflammatory Mediators in House Dust Mite-Induced Allergic Airways Disease.
van de Wetering C, Aboushousha R, Manuel AM, Chia SB, Erickson C, MacPherson MB, van der Velden JL, Anathy V, Dixon AE, Irvin CG, Poynter ME, van der Vliet A, Wouters EFM, Reynaert NL, Janssen-Heininger YMW. van de Wetering C, et al. Among authors: macpherson mb. J Immunol. 2020 Feb 15;204(4):763-774. doi: 10.4049/jimmunol.1901086. Epub 2020 Jan 10. J Immunol. 2020. PMID: 31924651 Free PMC article.
Dysregulation of Pyruvate Kinase M2 Promotes Inflammation in a Mouse Model of Obese Allergic Asthma.
Manuel AM, van de Wetering C, MacPherson M, Erickson C, Murray C, Aboushousha R, van der Velden J, Dixon AE, Poynter ME, Irvin CG, Taatjes DJ, van der Vliet A, Anathy V, Janssen-Heininger YMW. Manuel AM, et al. Among authors: macpherson m. Am J Respir Cell Mol Biol. 2021 Jun;64(6):709-721. doi: 10.1165/rcmb.2020-0512OC. Am J Respir Cell Mol Biol. 2021. PMID: 33662229 Free PMC article.
Glutathionylation chemistry promotes interleukin-1 beta-mediated glycolytic reprogramming and pro-inflammatory signaling in lung epithelial cells.
Aboushousha R, Elko E, Chia SB, Manuel AM, van de Wetering C, van der Velden J, MacPherson M, Erickson C, Reisz JA, D'Alessandro A, Wouters EFM, Reynaert NL, Lam YW, Anathy V, van der Vliet A, Seward DJ, Janssen-Heininger YMW. Aboushousha R, et al. Among authors: macpherson m. FASEB J. 2021 May;35(5):e21525. doi: 10.1096/fj.202002687RR. FASEB J. 2021. PMID: 33817836 Free PMC article.
Glutathione-S-transferase P promotes glycolysis in asthma in association with oxidation of pyruvate kinase M2.
van de Wetering C, Manuel AM, Sharafi M, Aboushousha R, Qian X, Erickson C, MacPherson M, Chan G, Adcock IM, ZounematKermani N, Schleich F, Louis R, Bohrnsen E, D'Alessandro A, Wouters EF, Reynaert NL, Li J, Wolf CR, Henderson CJ, Lundblad LKA, Poynter ME, Dixon AE, Irvin CG, van der Vliet A, van der Velden JL, Janssen-Heininger YM. van de Wetering C, et al. Among authors: macpherson m. Redox Biol. 2021 Nov;47:102160. doi: 10.1016/j.redox.2021.102160. Epub 2021 Oct 3. Redox Biol. 2021. PMID: 34624602 Free PMC article.
289 results