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Enolase represents a metabolic checkpoint controlling the differential exhaustion programmes of hepatitis virus-specific CD8+ T cells.
Winkler F, Hipp AV, Ramirez C, Martin B, Villa M, Neuwirt E, Gorka O, Aerssens J, Johansson SE, Rana N, Llewellyn-Lacey S, Price DA, Panning M, Groß O, Pearce EL, Hermann CM, Schumann K, Hannibal L, Neumann-Haefelin C, Boettler T, Knolle P, Hofmann M, Wohlleber D, Thimme R, Bengsch B. Winkler F, et al. Among authors: llewellyn lacey s. Gut. 2023 Oct;72(10):1971-1984. doi: 10.1136/gutjnl-2022-328734. Epub 2023 Aug 4. Gut. 2023. PMID: 37541771 Free PMC article.
Phenotypic and functional differences of HBV core-specific versus HBV polymerase-specific CD8+ T cells in chronically HBV-infected patients with low viral load.
Schuch A, Salimi Alizei E, Heim K, Wieland D, Kiraithe MM, Kemming J, Llewellyn-Lacey S, Sogukpinar Ö, Ni Y, Urban S, Zimmermann P, Nassal M, Emmerich F, Price DA, Bengsch B, Luxenburger H, Neumann-Haefelin C, Hofmann M, Thimme R. Schuch A, et al. Gut. 2019 May;68(5):905-915. doi: 10.1136/gutjnl-2018-316641. Epub 2019 Jan 8. Gut. 2019. PMID: 30622109 Free article.
TOX defines the degree of CD8+ T cell dysfunction in distinct phases of chronic HBV infection.
Heim K, Binder B, Sagar, Wieland D, Hensel N, Llewellyn-Lacey S, Gostick E, Price DA, Emmerich F, Vingerhoet H, Kraft ARM, Cornberg M, Boettler T, Neumann-Haefelin C, Zehn D, Bengsch B, Hofmann M, Thimme R. Heim K, et al. Gut. 2020 Oct 23;70(8):1550-60. doi: 10.1136/gutjnl-2020-322404. Online ahead of print. Gut. 2020. PMID: 33097558 Free PMC article.
Characterization of pre-existing and induced SARS-CoV-2-specific CD8+ T cells.
Schulien I, Kemming J, Oberhardt V, Wild K, Seidel LM, Killmer S, Sagar, Daul F, Salvat Lago M, Decker A, Luxenburger H, Binder B, Bettinger D, Sogukpinar O, Rieg S, Panning M, Huzly D, Schwemmle M, Kochs G, Waller CF, Nieters A, Duerschmied D, Emmerich F, Mei HE, Schulz AR, Llewellyn-Lacey S, Price DA, Boettler T, Bengsch B, Thimme R, Hofmann M, Neumann-Haefelin C. Schulien I, et al. Nat Med. 2021 Jan;27(1):78-85. doi: 10.1038/s41591-020-01143-2. Epub 2020 Nov 12. Nat Med. 2021. PMID: 33184509
Memory-like HCV-specific CD8+ T cells retain a molecular scar after cure of chronic HCV infection.
Hensel N, Gu Z, Sagar, Wieland D, Jechow K, Kemming J, Llewellyn-Lacey S, Gostick E, Sogukpinar O, Emmerich F, Price DA, Bengsch B, Boettler T, Neumann-Haefelin C, Eils R, Conrad C, Bartenschlager R, Grün D, Ishaque N, Thimme R, Hofmann M. Hensel N, et al. Nat Immunol. 2021 Feb;22(2):229-239. doi: 10.1038/s41590-020-00817-w. Epub 2021 Jan 4. Nat Immunol. 2021. PMID: 33398179
Mechanisms of CD8+ T-cell failure in chronic hepatitis E virus infection.
Kemming J, Gundlach S, Panning M, Huzly D, Huang J, Lütgehetmann M, Pischke S, Schulze Zur Wiesch J, Emmerich F, Llewellyn-Lacey S, Price DA, Tanriver Y, Warnatz K, Boettler T, Thimme R, Hofmann M, Fischer N, Neumann-Haefelin C. Kemming J, et al. Among authors: llewellyn lacey s. J Hepatol. 2022 Oct;77(4):978-990. doi: 10.1016/j.jhep.2022.05.019. Epub 2022 May 28. J Hepatol. 2022. PMID: 35636577 Free article.
40 results