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Conditional transgenic mice expressing C-terminally truncated human alpha-synuclein (alphaSyn119) exhibit reduced striatal dopamine without loss of nigrostriatal pathway dopaminergic neurons.
Daher JP, Ying M, Banerjee R, McDonald RS, Hahn MD, Yang L, Flint Beal M, Thomas B, Dawson VL, Dawson TM, Moore DJ. Daher JP, et al. Among authors: moore dj. Mol Neurodegener. 2009 Jul 24;4:34. doi: 10.1186/1750-1326-4-34. Mol Neurodegener. 2009. PMID: 19630976 Free PMC article.
Genetic mouse models of neurodegenerative diseases.
Trancikova A, Ramonet D, Moore DJ. Trancikova A, et al. Among authors: moore dj. Prog Mol Biol Transl Sci. 2011;100:419-82. doi: 10.1016/B978-0-12-384878-9.00012-1. Prog Mol Biol Transl Sci. 2011. PMID: 21377633 Review.
α-Synuclein in central nervous system and from erythrocytes, mammalian cells, and Escherichia coli exists predominantly as disordered monomer.
Fauvet B, Mbefo MK, Fares MB, Desobry C, Michael S, Ardah MT, Tsika E, Coune P, Prudent M, Lion N, Eliezer D, Moore DJ, Schneider B, Aebischer P, El-Agnaf OM, Masliah E, Lashuel HA. Fauvet B, et al. Among authors: moore dj. J Biol Chem. 2012 May 4;287(19):15345-64. doi: 10.1074/jbc.M111.318949. Epub 2012 Feb 7. J Biol Chem. 2012. PMID: 22315227 Free PMC article.
Mechanisms of LRRK2-mediated neurodegeneration.
Tsika E, Moore DJ. Tsika E, et al. Among authors: moore dj. Curr Neurol Neurosci Rep. 2012 Jun;12(3):251-60. doi: 10.1007/s11910-012-0265-8. Curr Neurol Neurosci Rep. 2012. PMID: 22441981 Free article. Review.
LRRK2 secretion in exosomes is regulated by 14-3-3.
Fraser KB, Moehle MS, Daher JP, Webber PJ, Williams JY, Stewart CA, Yacoubian TA, Cowell RM, Dokland T, Ye T, Chen D, Siegal GP, Galemmo RA, Tsika E, Moore DJ, Standaert DG, Kojima K, Mobley JA, West AB. Fraser KB, et al. Among authors: moore dj. Hum Mol Genet. 2013 Dec 15;22(24):4988-5000. doi: 10.1093/hmg/ddt346. Epub 2013 Jul 25. Hum Mol Genet. 2013. PMID: 23886663 Free PMC article.
1,002 results