Hardick D - Search Results

1

Inhibition of METTL3 Results in a Cell-Intrinsic Interferon Response That Enhances Antitumor Immunity.

Guirguis AA, Ofir-Rosenfeld Y, Knezevic K, Blackaby W, Hardick D, Chan YC, Motazedian A, Gillespie A, Vassiliadis D, Lam EYN, Tran K, Andrews B, Harbour ME, Vasiliauskaite L, Saunders CJ, Tsagkogeorga G, Azevedo A, Obacz J, Pilka ES, Carkill M, MacPherson L, Wainwright EN, Liddicoat B, Blyth BJ, Albertella MR, Rausch O, Dawson MA. Guirguis AA, et al. Among authors: hardick d. Cancer Discov. 2023 Oct 5;13(10):2228-2247. doi: 10.1158/2159-8290.CD-23-0007. Cancer Discov. 2023. PMID: 37548590

2

3,5-Diaryl-2-aminopyridines as a novel class of orally active antimalarials demonstrating single dose cure in mice and clinical candidate potential.

Younis Y, Douelle F, Feng TS, González Cabrera D, Le Manach C, Nchinda AT, Duffy S, White KL, Shackleford DM, Morizzi J, Mannila J, Katneni K, Bhamidipati R, Zabiulla KM, Joseph JT, Bashyam S, Waterson D, Witty MJ, Hardick D, Wittlin S, Avery V, Charman SA, Chibale K. Younis Y, et al. Among authors: hardick d. J Med Chem. 2012 Apr 12;55(7):3479-87. doi: 10.1021/jm3001373. Epub 2012 Mar 21. J Med Chem. 2012. PMID: 22390538

3

A comparative study of fragment screening methods on the p38α kinase: new methods, new insights.

Pollack SJ, Beyer KS, Lock C, Müller I, Sheppard D, Lipkin M, Hardick D, Blurton P, Leonard PM, Hubbard PA, Todd D, Richardson CM, Ahrens T, Baader M, Hafenbradl DO, Hilyard K, Bürli RW. Pollack SJ, et al. Among authors: hardick d. J Comput Aided Mol Des. 2011 Jul;25(7):677-87. doi: 10.1007/s10822-011-9454-9. Epub 2011 Jul 6. J Comput Aided Mol Des. 2011. PMID: 21732248 Free PMC article.

4

A study of (binap)(enyne)tetracarbonyldicobalt(0) complexes.

Gibson SE, Hardick DJ, Haycock PR, Kaufmann KA, Miyazaki A, Tozer MJ, White AJ. Gibson SE, et al. Among authors: hardick dj. Chemistry. 2007;13(25):7099-109. doi: 10.1002/chem.200700587. Chemistry. 2007. PMID: 17594711

5

Structure-activity relationships for analogues of the phenazine-based dual topoisomerase I/II inhibitor XR11576.

Wang S, Miller W, Milton J, Vicker N, Stewart A, Charlton P, Mistry P, Hardick D, Denny WA. Wang S, et al. Among authors: hardick d. Bioorg Med Chem Lett. 2002 Feb 11;12(3):415-8. doi: 10.1016/s0960-894x(01)00770-3. Bioorg Med Chem Lett. 2002. PMID: 11814810

6

Novel angular benzophenazines: dual topoisomerase I and topoisomerase II inhibitors as potential anticancer agents.

Vicker N, Burgess L, Chuckowree IS, Dodd R, Folkes AJ, Hardick DJ, Hancox TC, Miller W, Milton J, Sohal S, Wang S, Wren SP, Charlton PA, Dangerfield W, Liddle C, Mistry P, Stewart AJ, Denny WA. Vicker N, et al. Among authors: hardick dj. J Med Chem. 2002 Jan 31;45(3):721-39. doi: 10.1021/jm010329a. J Med Chem. 2002. PMID: 11806724

7

Novel reduced benzo[j]fluranthen-3-ones from Cladosporium cf. cladosporioides with cytokine production and tyrosine kinase inhibitory properties.

Wrigley SK, Ainsworth AM, Kau DA, Martin SM, Bahl S, Tang JS, Hardick DJ, Rawlins P, Sadheghi R, Moore M. Wrigley SK, et al. Among authors: hardick dj. J Antibiot (Tokyo). 2001 Jun;54(6):479-88. doi: 10.7164/antibiotics.54.479. J Antibiot (Tokyo). 2001. PMID: 11513036 Free article.

8

[3H]-Methyllycaconitine: a high affinity radioligand that labels invertebrate nicotinic acetylcholine receptors.

Lind RJ, Hardick DJ, Blagbrough IS, Potter BV, Wolstenholme AJ, Davies AR, Clough MS, Earley FG, Reynolds SE, Wonnacott S. Lind RJ, et al. Among authors: hardick dj. Insect Biochem Mol Biol. 2001 Apr 27;31(6-7):533-42. doi: 10.1016/s0965-1748(00)00153-3. Insect Biochem Mol Biol. 2001. PMID: 11267892

9

Characterisation of the binding of [3H]methyllycaconitine: a new radioligand for labelling alpha 7-type neuronal nicotinic acetylcholine receptors.

Davies AR, Hardick DJ, Blagbrough IS, Potter BV, Wolstenholme AJ, Wonnacott S. Davies AR, et al. Among authors: hardick dj. Neuropharmacology. 1999 May;38(5):679-90. doi: 10.1016/s0028-3908(98)00221-4. Neuropharmacology. 1999. PMID: 10340305

10

Structure-activity studies of bicyclic and tricyclic analogues of methyllycaconitine.

Davies AR, Hardick DJ, Blagbrough IS, Potter BV, Wolstenholme AJ, Wonnacott S. Davies AR, et al. Among authors: hardick dj. Biochem Soc Trans. 1997 Aug;25(3):545S. doi: 10.1042/bst025545s. Biochem Soc Trans. 1997. PMID: 9388759 No abstract available.

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