French JB - Search Results

1

Structure-Guided Discovery of N⁵-CAIR Mutase Inhibitors.

Belfon KKJ, Sharma N, Zigweid R, Bolejack M, Davies D, Edwards TE, Myler PJ, French JB. Belfon KKJ, et al. Among authors: french jb. Biochemistry. 2023 Sep 5;62(17):2587-2596. doi: 10.1021/acs.biochem.2c00705. Epub 2023 Aug 8. Biochemistry. 2023. PMID: 37552766 Free article.

2

Structural and Functional Characterization of the Histidine Phosphatase Domains of Human Sts-1 and Sts-2.

Zhou W, Yin Y, Weinheimer AS, Kaur N, Carpino N, French JB. Zhou W, et al. Among authors: french jb. Biochemistry. 2017 Sep 5;56(35):4637-4645. doi: 10.1021/acs.biochem.7b00638. Epub 2017 Aug 21. Biochemistry. 2017. PMID: 28759203 Free PMC article.

3

Structural and Functional Basis for Targeting Campylobacter jejuni Agmatine Deiminase To Overcome Antibiotic Resistance.

Shek R, Dattmore DA, Stives DP, Jackson AL, Chatfield CH, Hicks KA, French JB. Shek R, et al. Among authors: french jb. Biochemistry. 2017 Dec 26;56(51):6734-6742. doi: 10.1021/acs.biochem.7b00982. Epub 2017 Dec 14. Biochemistry. 2017. PMID: 29190068 Free PMC article.

4

Structural Determinants for Substrate Selectivity in Guanine Deaminase Enzymes of the Amidohydrolase Superfamily.

Shek R, Hilaire T, Sim J, French JB. Shek R, et al. Among authors: french jb. Biochemistry. 2019 Jul 30;58(30):3280-3292. doi: 10.1021/acs.biochem.9b00341. Epub 2019 Jul 19. Biochemistry. 2019. PMID: 31283204 Free PMC article.

5

Characterization of an Acinetobacter baumannii Monofunctional Phosphomethylpyrimidine Kinase That Is Inhibited by Pyridoxal Phosphate.

De Vitto H, Belfon KKJ, Sharma N, Toay S, Abendroth J, Dranow DM, Lukacs CM, Choi R, Udell HS, Willis S, Barrera G, Beyer O, Li TD, Hicks KA, Torelli AT, French JB. De Vitto H, et al. Among authors: french jb. Biochemistry. 2024 Feb 2. doi: 10.1021/acs.biochem.3c00640. Online ahead of print. Biochemistry. 2024. PMID: 38306231

6

High-resolution crystal structures of Streptococcus pneumoniae nicotinamidase with trapped intermediates provide insights into the catalytic mechanism and inhibition by aldehydes.

French JB, Cen Y, Sauve AA, Ealick SE. French JB, et al. Biochemistry. 2010 Oct 12;49(40):8803-12. doi: 10.1021/bi1012436. Epub 2010 Sep 20. Biochemistry. 2010. PMID: 20853856 Free PMC article.

7

Characterization of nicotinamidases: steady state kinetic parameters, classwide inhibition by nicotinaldehydes, and catalytic mechanism.

French JB, Cen Y, Vrablik TL, Xu P, Allen E, Hanna-Rose W, Sauve AA. French JB, et al. Biochemistry. 2010 Dec 14;49(49):10421-39. doi: 10.1021/bi1012518. Epub 2010 Nov 15. Biochemistry. 2010. PMID: 20979384 Free PMC article.

8

Mechanism of MenE inhibition by acyl-adenylate analogues and discovery of novel antibacterial agents.

Matarlo JS, Evans CE, Sharma I, Lavaud LJ, Ngo SC, Shek R, Rajashankar KR, French JB, Tan DS, Tonge PJ. Matarlo JS, et al. Among authors: french jb. Biochemistry. 2015 Oct 27;54(42):6514-6524. doi: 10.1021/acs.biochem.5b00966. Epub 2015 Oct 15. Biochemistry. 2015. PMID: 26394156 Free PMC article.

9

Structure of Klebsiella pneumoniae adenosine monophosphate nucleosidase.

Richardson BC, Shek R, Van Voorhis WC, French JB. Richardson BC, et al. Among authors: french jb. PLoS One. 2022 Oct 20;17(10):e0275023. doi: 10.1371/journal.pone.0275023. eCollection 2022. PLoS One. 2022. PMID: 36264993 Free PMC article.

10

Biochemical and structural characterization of a ureidoglycine aminotransferase in the Klebsiella pneumoniae uric acid catabolic pathway.

French JB, Ealick SE. French JB, et al. Biochemistry. 2010 Jul 27;49(29):5975-7. doi: 10.1021/bi1006755. Biochemistry. 2010. PMID: 20565126 Free PMC article.

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