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Defining the spatial distribution of extracellular adenosine revealed a myeloid-dependent immunosuppressive microenvironment in pancreatic ductal adenocarcinoma.
Graziano V, Dannhorn A, Hulme H, Williamson K, Buckley H, Karim SA, Wilson M, Lee SY, Kaistha BP, Islam S, Thaventhiran JED, Richards FM, Goodwin R, Brais R, Morton JP, Dovedi SJ, Schuller AG, Eyles J, Jodrell DI. Graziano V, et al. Among authors: goodwin r. J Immunother Cancer. 2023 Aug;11(8):e006457. doi: 10.1136/jitc-2022-006457. J Immunother Cancer. 2023. PMID: 37553182 Free PMC article.
Mass spectrometry imaging identifies palmitoylcarnitine as an immunological mediator during Salmonella Typhimurium infection.
Hulme HE, Meikle LM, Wessel H, Strittmatter N, Swales J, Thomson C, Nilsson A, Nibbs RJB, Milling S, Andren PE, Mackay CL, Dexter A, Bunch J, Goodwin RJA, Burchmore R, Wall DM. Hulme HE, et al. Among authors: goodwin rja. Sci Rep. 2017 Jun 5;7(1):2786. doi: 10.1038/s41598-017-03100-5. Sci Rep. 2017. PMID: 28584281 Free PMC article.
Intratumoral immunotherapy with TLR7/8 agonist MEDI9197 modulates the tumor microenvironment leading to enhanced activity when combined with other immunotherapies.
Mullins SR, Vasilakos JP, Deschler K, Grigsby I, Gillis P, John J, Elder MJ, Swales J, Timosenko E, Cooper Z, Dovedi SJ, Leishman AJ, Luheshi N, Elvecrog J, Tilahun A, Goodwin R, Herbst R, Tomai MA, Wilkinson RW. Mullins SR, et al. Among authors: goodwin r. J Immunother Cancer. 2019 Sep 11;7(1):244. doi: 10.1186/s40425-019-0724-8. J Immunother Cancer. 2019. PMID: 31511088 Free PMC article.
Universal Sample Preparation Unlocking Multimodal Molecular Tissue Imaging.
Dannhorn A, Kazanc E, Ling S, Nikula C, Karali E, Serra MP, Vorng JL, Inglese P, Maglennon G, Hamm G, Swales J, Strittmatter N, Barry ST, Sansom OJ, Poulogiannis G, Bunch J, Goodwin RJ, Takats Z. Dannhorn A, et al. Anal Chem. 2020 Aug 18;92(16):11080-11088. doi: 10.1021/acs.analchem.0c00826. Epub 2020 Jul 27. Anal Chem. 2020. PMID: 32519547
Comparison of 13 C MRI of hyperpolarized [1-13 C]pyruvate and lactate with the corresponding mass spectrometry images in a murine lymphoma model.
Fala M, Somai V, Dannhorn A, Hamm G, Gibson K, Couturier DL, Hesketh R, Wright AJ, Takats Z, Bunch J, Barry ST, Goodwin RJA, Brindle KM. Fala M, et al. Among authors: goodwin rja. Magn Reson Med. 2021 Jun;85(6):3027-3035. doi: 10.1002/mrm.28652. Epub 2021 Jan 9. Magn Reson Med. 2021. PMID: 33421253 Free PMC article.
Spatial visualization of comprehensive brain neurotransmitter systems and neuroactive substances by selective in situ chemical derivatization mass spectrometry imaging.
Shariatgorji R, Nilsson A, Fridjonsdottir E, Strittmatter N, Dannhorn A, Svenningsson P, Goodwin RJA, Odell LR, Andrén PE. Shariatgorji R, et al. Among authors: goodwin rja. Nat Protoc. 2021 Jul;16(7):3298-3321. doi: 10.1038/s41596-021-00538-w. Epub 2021 Jun 2. Nat Protoc. 2021. PMID: 34075230
Holistic Characterization of a Salmonella Typhimurium Infection Model Using Integrated Molecular Imaging.
Strittmatter N, Kanvatirth P, Inglese P, Race AM, Nilsson A, Dannhorn A, Kudo H, Goldin RD, Ling S, Wong E, Seeliger F, Serra MP, Hoffmann S, Maglennon G, Hamm G, Atkinson J, Jones S, Bunch J, Andrén PE, Takats Z, Goodwin RJA, Mastroeni P. Strittmatter N, et al. J Am Soc Mass Spectrom. 2021 Dec 1;32(12):2791-2802. doi: 10.1021/jasms.1c00240. Epub 2021 Nov 12. J Am Soc Mass Spectrom. 2021. PMID: 34767352
1,055 results