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Defining the spatial distribution of extracellular adenosine revealed a myeloid-dependent immunosuppressive microenvironment in pancreatic ductal adenocarcinoma.
Graziano V, Dannhorn A, Hulme H, Williamson K, Buckley H, Karim SA, Wilson M, Lee SY, Kaistha BP, Islam S, Thaventhiran JED, Richards FM, Goodwin R, Brais R, Morton JP, Dovedi SJ, Schuller AG, Eyles J, Jodrell DI. Graziano V, et al. Among authors: kaistha bp. J Immunother Cancer. 2023 Aug;11(8):e006457. doi: 10.1136/jitc-2022-006457. J Immunother Cancer. 2023. PMID: 37553182 Free PMC article.
Efficacy and pharmacodynamic effect of anti-CD73 and anti-PD-L1 monoclonal antibodies in combination with cytotoxic therapy: observations from mouse tumor models.
Kaistha BP, Kar G, Dannhorn A, Watkins A, Opoku-Ansah G, Ilieva K, Mullins S, Anderton J, Galvani E, Garcon F, Lapointe JM, Brown L, Hair J, Slidel T, Luheshi N, Ryan K, Hardaker E, Dovedi S, Kumar R, Wilkinson RW, Hammond SA, Eyles J. Kaistha BP, et al. Cancer Biol Ther. 2024 Dec 31;25(1):2296048. doi: 10.1080/15384047.2023.2296048. Epub 2024 Jan 11. Cancer Biol Ther. 2024. PMID: 38206570 Free PMC article.
Method To Visualize the Intratumor Distribution and Impact of Gemcitabine in Pancreatic Ductal Adenocarcinoma by Multimodal Imaging.
Strittmatter N, Richards FM, Race AM, Ling S, Sutton D, Nilsson A, Wallez Y, Barnes J, Maglennon G, Gopinathan A, Brais R, Wong E, Serra MP, Atkinson J, Smith A, Wilson J, Hamm G, Johnson TI, Dunlop CR, Kaistha BP, Bunch J, Sansom OJ, Takats Z, Andrén PE, Lau A, Barry ST, Goodwin RJA, Jodrell DI. Strittmatter N, et al. Among authors: kaistha bp. Anal Chem. 2022 Jan 25;94(3):1795-1803. doi: 10.1021/acs.analchem.1c04579. Epub 2022 Jan 10. Anal Chem. 2022. PMID: 35005896
PLAC8 Localizes to the Inner Plasma Membrane of Pancreatic Cancer Cells and Regulates Cell Growth and Disease Progression through Critical Cell-Cycle Regulatory Pathways.
Kaistha BP, Lorenz H, Schmidt H, Sipos B, Pawlak M, Gierke B, Kreider R, Lankat-Buttgereit B, Sauer M, Fiedler L, Krattenmacher A, Geisel B, Kraus JM, Frese KK, Kelkenberg S, Giese NA, Kestler HA, Gress TM, Buchholz M. Kaistha BP, et al. Cancer Res. 2016 Jan 1;76(1):96-107. doi: 10.1158/0008-5472.CAN-15-0216. Epub 2015 Dec 15. Cancer Res. 2016. PMID: 26669866
Renal fibrosis is attenuated by targeted disruption of KCa3.1 potassium channels.
Grgic I, Kiss E, Kaistha BP, Busch C, Kloss M, Sautter J, Müller A, Kaistha A, Schmidt C, Raman G, Wulff H, Strutz F, Gröne HJ, Köhler R, Hoyer J. Grgic I, et al. Among authors: kaistha bp. Proc Natl Acad Sci U S A. 2009 Aug 25;106(34):14518-23. doi: 10.1073/pnas.0903458106. Epub 2009 Aug 13. Proc Natl Acad Sci U S A. 2009. PMID: 19706538 Free PMC article.
Genetic deficit of SK3 and IK1 channels disrupts the endothelium-derived hyperpolarizing factor vasodilator pathway and causes hypertension.
Brähler S, Kaistha A, Schmidt VJ, Wölfle SE, Busch C, Kaistha BP, Kacik M, Hasenau AL, Grgic I, Si H, Bond CT, Adelman JP, Wulff H, de Wit C, Hoyer J, Köhler R. Brähler S, et al. Among authors: kaistha bp. Circulation. 2009 May 5;119(17):2323-32. doi: 10.1161/CIRCULATIONAHA.108.846634. Epub 2009 Apr 20. Circulation. 2009. PMID: 19380617 Free article.
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