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The Engineered Lysin, CF-370, is Active Against Antibiotic-Resistant Gram-Negative Pathogens In vitro and Synergizes with Meropenem in Experimental Pseudomonas aeruginosa Pneumonia.
Sauve K, Watson A, Oh JT, Swift S, Vila-Farres X, Abdelhady W, Xiong YQ, LeHoux D, Woodnutt G, Bayer AS, Schuch R. Sauve K, et al. Among authors: vila farres x. J Infect Dis. 2024 Feb 15:jiae027. doi: 10.1093/infdis/jiae027. Online ahead of print. J Infect Dis. 2024. PMID: 38366561
Rapid bacteriolysis of Staphylococcus aureus by lysin exebacase.
Vila-Farres X, Sauve K, Oh J, Swift S, DeJonge B, Ambler JE, Schuch R. Vila-Farres X, et al. Microbiol Spectr. 2023 Aug 10;11(5):e0190623. doi: 10.1128/spectrum.01906-23. Online ahead of print. Microbiol Spectr. 2023. PMID: 37561151 Free PMC article.
Synergistic activity of an OmpA inhibitor and colistin against colistin-resistant Acinetobacter baumannii: mechanistic analysis and in vivo efficacy.
Parra-Millán R, Vila-Farrés X, Ayerbe-Algaba R, Varese M, Sánchez-Encinales V, Bayó N, Pachón-Ibáñez ME, Teixidó M, Vila J, Pachón J, Giralt E, Smani Y. Parra-Millán R, et al. Among authors: vila farres x. J Antimicrob Chemother. 2018 Dec 1;73(12):3405-3412. doi: 10.1093/jac/dky343. J Antimicrob Chemother. 2018. PMID: 30188994 Free article.
Corrigendum: Commensal bacteria make GPCR ligands that mimic human signalling molecules.
Cohen LJ, Esterhazy D, Kim SH, Lemetre C, Aguilar RR, Gordon EA, Pickard AJ, Cross JR, Emiliano AB, Han SM, Chu J, Vila-Farres X, Kaplitt J, Rogoz A, Calle PY, Hunter C, Bitok JK, Brady SF. Cohen LJ, et al. Among authors: vila farres x. Nature. 2018 Apr 4;556(7699):135. doi: 10.1038/nature25997. Nature. 2018. PMID: 29620727
Combating virulence of Gram-negative bacilli by OmpA inhibition.
Vila-Farrés X, Parra-Millán R, Sánchez-Encinales V, Varese M, Ayerbe-Algaba R, Bayó N, Guardiola S, Pachón-Ibáñez ME, Kotev M, García J, Teixidó M, Vila J, Pachón J, Giralt E, Smani Y. Vila-Farrés X, et al. Sci Rep. 2017 Oct 31;7(1):14683. doi: 10.1038/s41598-017-14972-y. Sci Rep. 2017. PMID: 29089624 Free PMC article.
Commensal bacteria make GPCR ligands that mimic human signalling molecules.
Cohen LJ, Esterhazy D, Kim SH, Lemetre C, Aguilar RR, Gordon EA, Pickard AJ, Cross JR, Emiliano AB, Han SM, Chu J, Vila-Farres X, Kaplitt J, Rogoz A, Calle PY, Hunter C, Bitok JK, Brady SF. Cohen LJ, et al. Among authors: vila farres x. Nature. 2017 Sep 7;549(7670):48-53. doi: 10.1038/nature23874. Epub 2017 Aug 30. Nature. 2017. PMID: 28854168 Free PMC article.
25 results