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Automated antigen assays display a high heterogeneity for the detection of SARS-CoV-2 variants of concern, including several Omicron sublineages.
Osterman A, Krenn F, Iglhaut M, Badell I, Lehner A, Späth PM, Stern M, Both H, Bender S, Muenchhoff M, Graf A, Krebs S, Blum H, Grimmer T, Durner J, Czibere L, Dächert C, Grzimek-Koschewa N, Protzer U, Kaderali L, Baldauf HM, Keppler OT. Osterman A, et al. Among authors: dachert c. Med Microbiol Immunol. 2023 Oct;212(5):307-322. doi: 10.1007/s00430-023-00774-9. Epub 2023 Aug 10. Med Microbiol Immunol. 2023. PMID: 37561226 Free PMC article.
Stochastic dynamics of Type-I interferon responses.
Maier BD, Aguilera LU, Sahle S, Mutz P, Kalra P, Dächert C, Bartenschlager R, Binder M, Kummer U. Maier BD, et al. Among authors: dachert c. PLoS Comput Biol. 2022 Oct 21;18(10):e1010623. doi: 10.1371/journal.pcbi.1010623. eCollection 2022 Oct. PLoS Comput Biol. 2022. PMID: 36269758 Free PMC article.
Disentangling molecular mechanisms regulating sensitization of interferon alpha signal transduction.
Kok F, Rosenblatt M, Teusel M, Nizharadze T, Gonçalves Magalhães V, Dächert C, Maiwald T, Vlasov A, Wäsch M, Tyufekchieva S, Hoffmann K, Damm G, Seehofer D, Boettler T, Binder M, Timmer J, Schilling M, Klingmüller U. Kok F, et al. Among authors: dachert c. Mol Syst Biol. 2020 Jul;16(7):e8955. doi: 10.15252/msb.20198955. Mol Syst Biol. 2020. PMID: 32696599 Free PMC article.
Rapid and sensitive identification of omicron by variant-specific PCR and nanopore sequencing: paradigm for diagnostics of emerging SARS-CoV-2 variants.
Dächert C, Muenchhoff M, Graf A, Autenrieth H, Bender S, Mairhofer H, Wratil PR, Thieme S, Krebs S, Grzimek-Koschewa N, Blum H, Keppler OT. Dächert C, et al. Med Microbiol Immunol. 2022 Feb;211(1):71-77. doi: 10.1007/s00430-022-00728-7. Epub 2022 Jan 21. Med Microbiol Immunol. 2022. PMID: 35061086 Free PMC article.
Impaired detection of omicron by SARS-CoV-2 rapid antigen tests.
Osterman A, Badell I, Basara E, Stern M, Kriesel F, Eletreby M, Öztan GN, Huber M, Autenrieth H, Knabe R, Späth PM, Muenchhoff M, Graf A, Krebs S, Blum H, Durner J, Czibere L, Dächert C, Kaderali L, Baldauf HM, Keppler OT. Osterman A, et al. Among authors: dachert c. Med Microbiol Immunol. 2022 Jun;211(2-3):105-117. doi: 10.1007/s00430-022-00730-z. Epub 2022 Feb 20. Med Microbiol Immunol. 2022. PMID: 35187580 Free PMC article.
Variable detection of Omicron-BA.1 and -BA.2 by SARS-CoV-2 rapid antigen tests.
Osterman A, Badell I, Dächert C, Schneider N, Kaufmann AY, Öztan GN, Huber M, Späth PM, Stern M, Autenrieth H, Muenchhoff M, Graf A, Krebs S, Blum H, Czibere L, Durner J, Kaderali L, Baldauf HM, Keppler OT. Osterman A, et al. Among authors: dachert c. Med Microbiol Immunol. 2023 Feb;212(1):13-23. doi: 10.1007/s00430-022-00752-7. Epub 2022 Nov 12. Med Microbiol Immunol. 2023. PMID: 36370197 Free PMC article.
Potent high-avidity neutralizing antibodies and T cell responses after COVID-19 vaccination in individuals with B cell lymphoma and multiple myeloma.
Keppler-Hafkemeyer A, Greil C, Wratil PR, Shoumariyeh K, Stern M, Hafkemeyer A, Ashok D, Hollaus A, Lupoli G, Priller A, Bischof ML, Ihorst G, Engelhardt M, Marks R, Finke J, Bertrand H, Dächert C, Muenchhoff M, Badell I, Emmerich F, Halder H, Spaeth PM, Knolle PA, Protzer U, von Bergwelt-Baildon M, Duyster J, Hartmann TN, Moosmann A, Keppler OT. Keppler-Hafkemeyer A, et al. Among authors: dachert c. Nat Cancer. 2023 Jan;4(1):81-95. doi: 10.1038/s43018-022-00502-x. Epub 2022 Dec 21. Nat Cancer. 2023. PMID: 36543907 Free PMC article.
Antiviral drugs block replication of highly immune-evasive Omicron subvariants ex vivo, but fail to reduce tissue inflammation.
Dichtl S, Diem G, Jäger M, Zaderer V, Lupoli G, Dächert C, Muenchhoff M, Graf A, Blum H, Keppler OT, Lass-Flörl C, Weiss G, Wilflingseder D, Posch W. Dichtl S, et al. Among authors: dachert c. Antiviral Res. 2023 May;213:105581. doi: 10.1016/j.antiviral.2023.105581. Epub 2023 Mar 23. Antiviral Res. 2023. PMID: 36965526 Free PMC article.
22 results