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Local delivery of hrBMP4 as an anticancer therapy in patients with recurrent glioblastoma: a first-in-human phase 1 dose escalation trial.
Bos EM, Binda E, Verploegh ISC, Wembacher E, Hoefnagel D, Balvers RK, Korporaal AL, Conidi A, Warnert EAH, Trivieri N, Visioli A, Zaccarini P, Caiola L, van Wijck R, van der Spek P, Huylebroeck D, Leenstra S, Lamfers MLM, Ram Z, Westphal M, Noske D, Legnani F, DiMeco F, Vescovi AL, Dirven CMF. Bos EM, et al. Among authors: dirven cmf. Mol Cancer. 2023 Aug 10;22(1):129. doi: 10.1186/s12943-023-01835-6. Mol Cancer. 2023. PMID: 37563568 Free PMC article. Clinical Trial.
Oncolytic adenoviruses for treatment of brain tumours.
Dirven CM, van Beusechem VW, Lamfers ML, Grill J, Gerritsen WR, Vandertop WP. Dirven CM, et al. Expert Opin Biol Ther. 2002 Dec;2(8):943-52. doi: 10.1517/14712598.2.8.943. Expert Opin Biol Ther. 2002. PMID: 12517272 Review.
Tissue inhibitor of metalloproteinase-3 expression from an oncolytic adenovirus inhibits matrix metalloproteinase activity in vivo without affecting antitumor efficacy in malignant glioma.
Lamfers ML, Gianni D, Tung CH, Idema S, Schagen FH, Carette JE, Quax PH, Van Beusechem VW, Vandertop WP, Dirven CM, Chiocca EA, Gerritsen WR. Lamfers ML, et al. Cancer Res. 2005 Oct 15;65(20):9398-405. doi: 10.1158/0008-5472.CAN-04-4264. Cancer Res. 2005. PMID: 16230403 Free article.
Cyclophosphamide increases transgene expression mediated by an oncolytic adenovirus in glioma-bearing mice monitored by bioluminescence imaging.
Lamfers ML, Fulci G, Gianni D, Tang Y, Kurozumi K, Kaur B, Moeniralm S, Saeki Y, Carette JE, Weissleder R, Vandertop WP, van Beusechem VW, Dirven CM, Chiocca EA. Lamfers ML, et al. Mol Ther. 2006 Dec;14(6):779-88. doi: 10.1016/j.ymthe.2006.08.008. Epub 2006 Sep 22. Mol Ther. 2006. PMID: 16996314 Free PMC article.
167 results