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GATA2 mitotic bookmarking is required for definitive haematopoiesis.
Silvério-Alves R, Kurochkin I, Rydström A, Vazquez Echegaray C, Haider J, Nicholls M, Rode C, Thelaus L, Lindgren AY, Ferreira AG, Brandão R, Larsson J, de Bruijn MFTR, Martin-Gonzalez J, Pereira CF. Silvério-Alves R, et al. Among authors: de bruijn mftr. Nat Commun. 2023 Aug 14;14(1):4645. doi: 10.1038/s41467-023-40391-x. Nat Commun. 2023. PMID: 37580379 Free PMC article.
A short history of hemogenic endothelium.
Swiers G, Rode C, Azzoni E, de Bruijn MF. Swiers G, et al. Blood Cells Mol Dis. 2013 Dec;51(4):206-12. doi: 10.1016/j.bcmd.2013.09.005. Epub 2013 Oct 4. Blood Cells Mol Dis. 2013. PMID: 24095001 Free PMC article. Review.
Early dynamic fate changes in haemogenic endothelium characterized at the single-cell level.
Swiers G, Baumann C, O'Rourke J, Giannoulatou E, Taylor S, Joshi A, Moignard V, Pina C, Bee T, Kokkaliaris KD, Yoshimoto M, Yoder MC, Frampton J, Schroeder T, Enver T, Göttgens B, de Bruijn MFTR. Swiers G, et al. Among authors: de bruijn mftr. Nat Commun. 2013;4:2924. doi: 10.1038/ncomms3924. Nat Commun. 2013. PMID: 24326267 Free PMC article.
The genome-wide impact of trisomy 21 on DNA methylation and its implications for hematopoiesis.
Muskens IS, Li S, Jackson T, Elliot N, Hansen HM, Myint SS, Pandey P, Schraw JM, Roy R, Anguiano J, Goudevenou K, Siegmund KD, Lupo PJ, de Bruijn MFTR, Walsh KM, Vyas P, Ma X, Roy A, Roberts I, Wiemels JL, de Smith AJ. Muskens IS, et al. Among authors: de bruijn mftr. Nat Commun. 2021 Feb 5;12(1):821. doi: 10.1038/s41467-021-21064-z. Nat Commun. 2021. PMID: 33547282 Free PMC article.
The onset of circulation triggers a metabolic switch required for endothelial to hematopoietic transition.
Azzoni E, Frontera V, Anselmi G, Rode C, James C, Deltcheva EM, Demian AS, Brown J, Barone C, Patelli A, Harman JR, Nicholls M, Conway SJ, Morrissey E, Jacobsen SEW, Sparrow DB, Harris AL, Enver T, de Bruijn MFTR. Azzoni E, et al. Among authors: de bruijn mftr. Cell Rep. 2021 Dec 14;37(11):110103. doi: 10.1016/j.celrep.2021.110103. Cell Rep. 2021. PMID: 34910918 Free PMC article.
Dynamic Runx1 chromatin boundaries affect gene expression in hematopoietic development.
Owens DDG, Anselmi G, Oudelaar AM, Downes DJ, Cavallo A, Harman JR, Schwessinger R, Bucakci A, Greder L, de Ornellas S, Jeziorska D, Telenius J, Hughes JR, de Bruijn MFTR. Owens DDG, et al. Among authors: de bruijn mftr. Nat Commun. 2022 Feb 9;13(1):773. doi: 10.1038/s41467-022-28376-8. Nat Commun. 2022. PMID: 35140205 Free PMC article.
59 results