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Endothelial AHR activity prevents lung barrier disruption in viral infection.
Major J, Crotta S, Finsterbusch K, Chakravarty P, Shah K, Frederico B, D'Antuono R, Green M, Meader L, Suarez-Bonnet A, Priestnall S, Stockinger B, Wack A. Major J, et al. Among authors: chakravarty p. Nature. 2023 Sep;621(7980):813-820. doi: 10.1038/s41586-023-06287-y. Epub 2023 Aug 16. Nature. 2023. PMID: 37587341 Free PMC article.
Blimp-1 and c-Maf regulate immune gene networks to protect against distinct pathways of pathobiont-induced colitis.
Alvarez-Martinez M, Cox LS, Pearson CF, Branchett WJ, Chakravarty P, Wu X, Slawinski H, Al-Dibouni A, Samelis VA, Gabryšová L, Priestnall SL, Suárez-Bonnet A, Mikolajczak A, Briscoe J, Powrie F, O'Garra A. Alvarez-Martinez M, et al. Among authors: chakravarty p. Nat Immunol. 2024 May;25(5):886-901. doi: 10.1038/s41590-024-01814-z. Epub 2024 Apr 12. Nat Immunol. 2024. PMID: 38609547 Free PMC article.
Distinct ontogenetic lineages dictate cDC2 heterogeneity.
Minutti CM, Piot C, Pereira da Costa M, Chakravarty P, Rogers N, Huerga Encabo H, Cardoso A, Loong J, Bessou G, Mionnet C, Langhorne J, Bonnet D, Dalod M, Tomasello E, Reis E Sousa C. Minutti CM, et al. Among authors: chakravarty p. Nat Immunol. 2024 Mar;25(3):448-461. doi: 10.1038/s41590-024-01745-9. Epub 2024 Feb 13. Nat Immunol. 2024. PMID: 38351322 Free PMC article.
Vitamin D regulates microbiome-dependent cancer immunity.
Giampazolias E, Pereira da Costa M, Lam KC, Lim KHJ, Cardoso A, Piot C, Chakravarty P, Blasche S, Patel S, Biram A, Castro-Dopico T, Buck MD, Rodrigues RR, Poulsen GJ, Palma-Duran SA, Rogers NC, Koufaki MA, Minutti CM, Wang P, Vdovin A, Frederico B, Childs E, Lee S, Simpson B, Iseppon A, Omenetti S, Kelly G, Goldstone R, Nye E, Suárez-Bonnet A, Priestnall SL, MacRae JI, Zelenay S, Patil KR, Litchfield K, Lee JC, Jess T, Goldszmid RS, Reis E Sousa C. Giampazolias E, et al. Among authors: chakravarty p. Science. 2024 Apr 26;384(6694):428-437. doi: 10.1126/science.adh7954. Epub 2024 Apr 25. Science. 2024. PMID: 38662827 Free PMC article.
PHGDH is required for germinal center formation and is a therapeutic target in MYC-driven lymphoma.
D'Avola A, Legrave N, Tajan M, Chakravarty P, Shearer RL, King HW, Kluckova K, Cheung EC, Clear AJ, Gunawan AS, Zhang L, James LK, MacRae JI, Gribben JG, Calado DP, Vousden KH, Riches JC. D'Avola A, et al. Among authors: chakravarty p. J Clin Invest. 2024 Feb 15;134(4):e179917. doi: 10.1172/JCI179917. J Clin Invest. 2024. PMID: 38357928 Free PMC article. No abstract available.
229 results