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Page 1
Pyruvate anaplerosis is a targetable vulnerability in persistent leukaemic stem cells.
Rattigan KM, Brabcova Z, Sarnello D, Zarou MM, Roy K, Kwan R, de Beauchamp L, Dawson A, Ianniciello A, Khalaf A, Kalkman ER, Scott MT, Dunn K, Sumpton D, Michie AM, Copland M, Tardito S, Gottlieb E, Vignir Helgason G. Rattigan KM, et al. Among authors: kalkman er. Nat Commun. 2023 Aug 17;14(1):4634. doi: 10.1038/s41467-023-40222-z. Nat Commun. 2023. PMID: 37591854 Free PMC article.
Arginine dependency is a therapeutically exploitable vulnerability in chronic myeloid leukaemic stem cells.
Rattigan KM, Zarou MM, Brabcova Z, Prasad B, Zerbst D, Sarnello D, Kalkman ER, Ianniciello A, Scott MT, Dunn K, Shokry E, Sumpton D, Copland M, Tardito S, Vande Voorde J, Mussai F, Cheng P, Helgason GV. Rattigan KM, et al. Among authors: kalkman er. EMBO Rep. 2023 Oct 9;24(10):e56279. doi: 10.15252/embr.202256279. Epub 2023 Jul 25. EMBO Rep. 2023. PMID: 37489735 Free PMC article.
ULK1 inhibition promotes oxidative stress-induced differentiation and sensitizes leukemic stem cells to targeted therapy.
Ianniciello A, Zarou MM, Rattigan KM, Scott M, Dawson A, Dunn K, Brabcova Z, Kalkman ER, Nixon C, Michie AM, Copland M, Vetrie D, Ambler M, Saxty B, Helgason GV. Ianniciello A, et al. Among authors: kalkman er. Sci Transl Med. 2021 Sep 29;13(613):eabd5016. doi: 10.1126/scitranslmed.abd5016. Epub 2021 Sep 29. Sci Transl Med. 2021. PMID: 34586834 Free PMC article.
Deazapurine Nucleoside Analogues for the Treatment of Trichomonas vaginalis.
Natto MJ, Hulpia F, Kalkman ER, Baillie S, Alhejeli A, Miyamoto Y, Eckmann L, Van Calenbergh S, de Koning HP. Natto MJ, et al. Among authors: kalkman er. ACS Infect Dis. 2021 Jun 11;7(6):1752-1764. doi: 10.1021/acsinfecdis.1c00075. Epub 2021 May 11. ACS Infect Dis. 2021. PMID: 33974405 Free PMC article.
Spatially segregated SNARE protein interactions in living fungal cells.
Valkonen M, Kalkman ER, Saloheimo M, Penttilä M, Read ND, Duncan RR. Valkonen M, et al. Among authors: kalkman er. J Biol Chem. 2007 Aug 3;282(31):22775-85. doi: 10.1074/jbc.M700916200. Epub 2007 Jun 5. J Biol Chem. 2007. PMID: 17553800 Free article.
Lessons from the genome sequence of Neurospora crassa: tracing the path from genomic blueprint to multicellular organism.
Borkovich KA, Alex LA, Yarden O, Freitag M, Turner GE, Read ND, Seiler S, Bell-Pedersen D, Paietta J, Plesofsky N, Plamann M, Goodrich-Tanrikulu M, Schulte U, Mannhaupt G, Nargang FE, Radford A, Selitrennikoff C, Galagan JE, Dunlap JC, Loros JJ, Catcheside D, Inoue H, Aramayo R, Polymenis M, Selker EU, Sachs MS, Marzluf GA, Paulsen I, Davis R, Ebbole DJ, Zelter A, Kalkman ER, O'Rourke R, Bowring F, Yeadon J, Ishii C, Suzuki K, Sakai W, Pratt R. Borkovich KA, et al. Among authors: kalkman er. Microbiol Mol Biol Rev. 2004 Mar;68(1):1-108. doi: 10.1128/MMBR.68.1.1-108.2004. Microbiol Mol Biol Rev. 2004. PMID: 15007097 Free PMC article. Review.
Does endocytosis occur in fungal hyphae?
Read ND, Kalkman ER. Read ND, et al. Among authors: kalkman er. Fungal Genet Biol. 2003 Aug;39(3):199-203. doi: 10.1016/s1087-1845(03)00045-8. Fungal Genet Biol. 2003. PMID: 12892632