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Intrinsically disordered domain of transcription factor TCF-1 is required for T cell developmental fidelity.
Goldman N, Chandra A, Johnson I, Sullivan MA, Patil AR, Vanderbeck A, Jay A, Zhou Y, Ferrari EK, Mayne L, Aguilan J, Xue HH, Faryabi RB, John Wherry E, Sidoli S, Maillard I, Vahedi G. Goldman N, et al. Among authors: faryabi rb. Nat Immunol. 2023 Oct;24(10):1698-1710. doi: 10.1038/s41590-023-01599-7. Epub 2023 Aug 17. Nat Immunol. 2023. PMID: 37592014 Free PMC article.
TooManyCells identifies and visualizes relationships of single-cell clades.
Schwartz GW, Zhou Y, Petrovic J, Fasolino M, Xu L, Shaffer SM, Pear WS, Vahedi G, Faryabi RB. Schwartz GW, et al. Among authors: faryabi rb. Nat Methods. 2020 Apr;17(4):405-413. doi: 10.1038/s41592-020-0748-5. Epub 2020 Mar 2. Nat Methods. 2020. PMID: 32123397 Free PMC article.
Oncogenic Notch Promotes Long-Range Regulatory Interactions within Hyperconnected 3D Cliques.
Petrovic J, Zhou Y, Fasolino M, Goldman N, Schwartz GW, Mumbach MR, Nguyen SC, Rome KS, Sela Y, Zapataro Z, Blacklow SC, Kruhlak MJ, Shi J, Aster JC, Joyce EF, Little SC, Vahedi G, Pear WS, Faryabi RB. Petrovic J, et al. Among authors: faryabi rb. Mol Cell. 2019 Mar 21;73(6):1174-1190.e12. doi: 10.1016/j.molcel.2019.01.006. Epub 2019 Feb 7. Mol Cell. 2019. PMID: 30745086 Free PMC article.
Genetic Variation in Type 1 Diabetes Reconfigures the 3D Chromatin Organization of T Cells and Alters Gene Expression.
Fasolino M, Goldman N, Wang W, Cattau B, Zhou Y, Petrovic J, Link VM, Cote A, Chandra A, Silverman M, Joyce EF, Little SC; HPAP Consortium; Kaestner KH, Naji A, Raj A, Henao-Mejia J, Faryabi RB, Vahedi G. Fasolino M, et al. Among authors: faryabi rb. Immunity. 2020 Feb 18;52(2):257-274.e11. doi: 10.1016/j.immuni.2020.01.003. Epub 2020 Feb 11. Immunity. 2020. PMID: 32049053 Free PMC article.
Single-cell multi-omics analysis of human pancreatic islets reveals novel cellular states in type 1 diabetes.
Fasolino M, Schwartz GW, Patil AR, Mongia A, Golson ML, Wang YJ, Morgan A, Liu C, Schug J, Liu J, Wu M, Traum D, Kondo A, May CL, Goldman N, Wang W, Feldman M, Moore JH, Japp AS, Betts MR; HPAP Consortium; Faryabi RB, Naji A, Kaestner KH, Vahedi G. Fasolino M, et al. Among authors: faryabi rb. Nat Metab. 2022 Feb;4(2):284-299. doi: 10.1038/s42255-022-00531-x. Epub 2022 Feb 28. Nat Metab. 2022. PMID: 35228745 Free PMC article.
ZMYND8-regulated IRF8 transcription axis is an acute myeloid leukemia dependency.
Cao Z, Budinich KA, Huang H, Ren D, Lu B, Zhang Z, Chen Q, Zhou Y, Huang YH, Alikarami F, Kingsley MC, Lenard AK, Wakabayashi A, Khandros E, Bailis W, Qi J, Carroll MP, Blobel GA, Faryabi RB, Bernt KM, Berger SL, Shi J. Cao Z, et al. Among authors: faryabi rb. Mol Cell. 2021 Sep 2;81(17):3604-3622.e10. doi: 10.1016/j.molcel.2021.07.018. Epub 2021 Aug 5. Mol Cell. 2021. PMID: 34358447 Free PMC article.
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