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Tumor-associated macrophages trigger MAIT cell dysfunction at the HCC invasive margin.
Ruf B, Bruhns M, Babaei S, Kedei N, Ma L, Revsine M, Benmebarek MR, Ma C, Heinrich B, Subramanyam V, Qi J, Wabitsch S, Green BL, Bauer KC, Myojin Y, Greten LT, McCallen JD, Huang P, Trehan R, Wang X, Nur A, Murphy Soika DQ, Pouzolles M, Evans CN, Chari R, Kleiner DE, Telford W, Dadkhah K, Ruchinskas A, Stovroff MK, Kang J, Oza K, Ruchirawat M, Kroemer A, Wang XW, Claassen M, Korangy F, Greten TF. Ruf B, et al. Among authors: subramanyam v. Cell. 2023 Aug 17;186(17):3686-3705.e32. doi: 10.1016/j.cell.2023.07.026. Cell. 2023. PMID: 37595566
Activating Mucosal-Associated Invariant T Cells Induces a Broad Antitumor Response.
Ruf B, Catania VV, Wabitsch S, Ma C, Diggs LP, Zhang Q, Heinrich B, Subramanyam V, Cui LL, Pouzolles M, Evans CN, Chari R, Sakai S, Oh S, Barry CE 3rd, Barber DL, Greten TF. Ruf B, et al. Among authors: subramanyam v. Cancer Immunol Res. 2021 Sep;9(9):1024-1034. doi: 10.1158/2326-6066.CIR-20-0925. Epub 2021 Jun 30. Cancer Immunol Res. 2021. PMID: 34193462 Free PMC article.
CD40-mediated immune cell activation enhances response to anti-PD-1 in murine intrahepatic cholangiocarcinoma.
Diggs LP, Ruf B, Ma C, Heinrich B, Cui L, Zhang Q, McVey JC, Wabitsch S, Heinrich S, Rosato U, Lai W, Subramanyam V, Longerich T, Loosen SH, Luedde T, Neumann UP, Desar S, Kleiner D, Gores G, Wang XW, Greten TF. Diggs LP, et al. Among authors: subramanyam v. J Hepatol. 2021 May;74(5):1145-1154. doi: 10.1016/j.jhep.2020.11.037. Epub 2020 Dec 1. J Hepatol. 2021. PMID: 33276030 Free PMC article.
Gut Microbiome Directs Hepatocytes to Recruit MDSCs and Promote Cholangiocarcinoma.
Zhang Q, Ma C, Duan Y, Heinrich B, Rosato U, Diggs LP, Ma L, Roy S, Fu Q, Brown ZJ, Wabitsch S, Thovarai V, Fu J, Feng D, Ruf B, Cui LL, Subramanyam V, Frank KM, Wang S, Kleiner DE, Ritz T, Rupp C, Gao B, Longerich T, Kroemer A, Wang XW, Ruchirawat M, Korangy F, Schnabl B, Trinchieri G, Greten TF. Zhang Q, et al. Among authors: subramanyam v. Cancer Discov. 2021 May;11(5):1248-1267. doi: 10.1158/2159-8290.CD-20-0304. Epub 2020 Dec 15. Cancer Discov. 2021. PMID: 33323397 Free PMC article.
The tumour microenvironment shapes innate lymphoid cells in patients with hepatocellular carcinoma.
Heinrich B, Gertz EM, Schäffer AA, Craig A, Ruf B, Subramanyam V, McVey JC, Diggs LP, Heinrich S, Rosato U, Ma C, Yan C, Hu Y, Zhao Y, Shen TW, Kapoor V, Telford W, Kleiner DE, Stovroff MK, Dhani HS, Kang J, Fishbein T, Wang XW, Ruppin E, Kroemer A, Greten TF, Korangy F. Heinrich B, et al. Among authors: subramanyam v. Gut. 2022 Jun;71(6):1161-1175. doi: 10.1136/gutjnl-2021-325288. Epub 2021 Aug 2. Gut. 2022. PMID: 34340996 Free PMC article.
Steatohepatitis Impairs T-cell-Directed Immunotherapies Against Liver Tumors in Mice.
Heinrich B, Brown ZJ, Diggs LP, Vormehr M, Ma C, Subramanyam V, Rosato U, Ruf B, Walz JS, McVey JC, Wabitsch S, Fu Q, Yu SJ, Zhang Q, Lai CW, Sahin U, Greten TF. Heinrich B, et al. Among authors: subramanyam v. Gastroenterology. 2021 Jan;160(1):331-345.e6. doi: 10.1053/j.gastro.2020.09.031. Epub 2020 Oct 1. Gastroenterology. 2021. PMID: 33010248 Free PMC article.
ENPP1 is an innate immune checkpoint of the anticancer cGAMP-STING pathway in breast cancer.
Wang S, Böhnert V, Joseph AJ, Sudaryo V, Skariah G, Swinderman JT, Yu FB, Subramanyam V, Wolf DM, Lyu X, Gilbert LA, Van't Veer LJ, Goodarzi H, Li L. Wang S, et al. Among authors: subramanyam v. Proc Natl Acad Sci U S A. 2023 Dec 26;120(52):e2313693120. doi: 10.1073/pnas.2313693120. Epub 2023 Dec 20. Proc Natl Acad Sci U S A. 2023. PMID: 38117852 Free PMC article.
71 results