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Discovery of GS-5245 (Obeldesivir), an Oral Prodrug of Nucleoside GS-441524 That Exhibits Antiviral Efficacy in SARS-CoV-2-Infected African Green Monkeys.
J Med Chem. 2023 Sep 14;66(17):11701-11717. doi: 10.1021/acs.jmedchem.3c00750. Epub 2023 Aug 19.
J Med Chem. 2023.
PMID: 37596939
In Vitro Selection of Remdesivir-Resistant SARS-CoV-2 Demonstrates High Barrier to Resistance.
Checkmahomed L, Carbonneau J, Du Pont V, Riola NC, Perry JK, Li J, Paré B, Simpson SM, Smith MA, Porter DP, Boivin G.
Checkmahomed L, et al. Among authors: riola nc.
Antimicrob Agents Chemother. 2022 Jul 19;66(7):e0019822. doi: 10.1128/aac.00198-22. Epub 2022 Jun 16.
Antimicrob Agents Chemother. 2022.
PMID: 35708323
Free PMC article.
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