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OGT prevents DNA demethylation and suppresses the expression of transposable elements in heterochromatin by restraining TET activity genome-wide.
Sepulveda H, Li X, Yue X, Carlos Angel J, Arteaga-Vazquez LJ, Brown C, Brunelli M, Jansz N, Puddu F, Scotcher J, Creed P, Kennedy P, Manriquez C, Myers SA, Crawford R, Faulkner GJ, Rao A. Sepulveda H, et al. Among authors: puddu f. bioRxiv [Preprint]. 2024 Jan 31:2024.01.31.578097. doi: 10.1101/2024.01.31.578097. bioRxiv. 2024. PMID: 38352366 Free PMC article. Preprint.
Large-scale exome sequence analysis identifies sex- and age-specific determinants of obesity.
Kaisinger LR, Kentistou KA, Stankovic S, Gardner EJ, Day FR, Zhao Y, Mörseburg A, Carnie CJ, Zagnoli-Vieira G, Puddu F, Jackson SP, O'Rahilly S, Farooqi IS, Dearden L, Pantaleão LC, Ozanne SE, Ong KK, Perry JRB. Kaisinger LR, et al. Among authors: puddu f. Cell Genom. 2023 Aug 2;3(8):100362. doi: 10.1016/j.xgen.2023.100362. eCollection 2023 Aug 9. Cell Genom. 2023. PMID: 37601970 Free PMC article.
Mutagenic mechanisms of cancer-associated DNA polymerase ϵ alleles.
Herzog M, Alonso-Perez E, Salguero I, Warringer J, Adams DJ, Jackson SP, Puddu F. Herzog M, et al. Among authors: puddu f. Nucleic Acids Res. 2021 Apr 19;49(7):3919-3931. doi: 10.1093/nar/gkab160. Nucleic Acids Res. 2021. PMID: 33764464 Free PMC article.
Trajectory and uniqueness of mutational signatures in yeast mutators.
Loeillet S, Herzog M, Puddu F, Legoix P, Baulande S, Jackson SP, Nicolas AG. Loeillet S, et al. Among authors: puddu f. Proc Natl Acad Sci U S A. 2020 Oct 6;117(40):24947-24956. doi: 10.1073/pnas.2011332117. Epub 2020 Sep 23. Proc Natl Acad Sci U S A. 2020. PMID: 32968016 Free PMC article.
Genome architecture and stability in the Saccharomyces cerevisiae knockout collection.
Puddu F, Herzog M, Selivanova A, Wang S, Zhu J, Klein-Lavi S, Gordon M, Meirman R, Millan-Zambrano G, Ayestaran I, Salguero I, Sharan R, Li R, Kupiec M, Jackson SP. Puddu F, et al. Nature. 2019 Sep;573(7774):416-420. doi: 10.1038/s41586-019-1549-9. Epub 2019 Sep 11. Nature. 2019. PMID: 31511699 Free PMC article.
Phosphorylation of Histone H4T80 Triggers DNA Damage Checkpoint Recovery.
Millan-Zambrano G, Santos-Rosa H, Puddu F, Robson SC, Jackson SP, Kouzarides T. Millan-Zambrano G, et al. Among authors: puddu f. Mol Cell. 2018 Nov 15;72(4):625-635.e4. doi: 10.1016/j.molcel.2018.09.023. Epub 2018 Oct 25. Mol Cell. 2018. PMID: 30454561 Free PMC article.
Chromatin determinants impart camptothecin sensitivity.
Puddu F, Salguero I, Herzog M, Geisler NJ, Costanzo V, Jackson SP. Puddu F, et al. EMBO Rep. 2017 Jun;18(6):1000-1012. doi: 10.15252/embr.201643560. Epub 2017 Apr 7. EMBO Rep. 2017. PMID: 28389464 Free PMC article.
Synthetic viability genomic screening defines Sae2 function in DNA repair.
Puddu F, Oelschlaegel T, Guerini I, Geisler NJ, Niu H, Herzog M, Salguero I, Ochoa-Montaño B, Viré E, Sung P, Adams DJ, Keane TM, Jackson SP. Puddu F, et al. EMBO J. 2015 Jun 3;34(11):1509-22. doi: 10.15252/embj.201590973. Epub 2015 Apr 21. EMBO J. 2015. PMID: 25899817 Free PMC article.
15 results