Nathan JA - Search Results

1

Glutarate regulates T cell metabolism and anti-tumour immunity.

Minogue E, Cunha PP, Wadsworth BJ, Grice GL, Sah-Teli SK, Hughes R, Bargiela D, Quaranta A, Zurita J, Antrobus R, Velica P, Barbieri L, Wheelock CE, Koivunen P, Nathan JA, Foskolou IP, Johnson RS. Minogue E, et al. Among authors: nathan ja. Nat Metab. 2023 Oct;5(10):1747-1764. doi: 10.1038/s42255-023-00855-2. Epub 2023 Aug 21. Nat Metab. 2023. PMID: 37605057 Free PMC article.

2

The Proteasome Distinguishes between Heterotypic and Homotypic Lysine-11-Linked Polyubiquitin Chains.

Grice GL, Lobb IT, Weekes MP, Gygi SP, Antrobus R, Nathan JA. Grice GL, et al. Among authors: nathan ja. Cell Rep. 2015 Jul 28;12(4):545-53. doi: 10.1016/j.celrep.2015.06.061. Epub 2015 Jul 16. Cell Rep. 2015. PMID: 26190103 Free PMC article.

3

The recognition of ubiquitinated proteins by the proteasome.

Grice GL, Nathan JA. Grice GL, et al. Among authors: nathan ja. Cell Mol Life Sci. 2016 Sep;73(18):3497-506. doi: 10.1007/s00018-016-2255-5. Epub 2016 May 2. Cell Mol Life Sci. 2016. PMID: 27137187 Free PMC article. Review.

4

Mitochondrial Protein Lipoylation and the 2-Oxoglutarate Dehydrogenase Complex Controls HIF1α Stability in Aerobic Conditions.

Burr SP, Costa AS, Grice GL, Timms RT, Lobb IT, Freisinger P, Dodd RB, Dougan G, Lehner PJ, Frezza C, Nathan JA. Burr SP, et al. Among authors: nathan ja. Cell Metab. 2016 Nov 8;24(5):740-752. doi: 10.1016/j.cmet.2016.09.015. Epub 2016 Oct 27. Cell Metab. 2016. PMID: 27923773 Free PMC article.

5

The vacuolar-ATPase complex and assembly factors, TMEM199 and CCDC115, control HIF1α prolyl hydroxylation by regulating cellular iron levels.

Miles AL, Burr SP, Grice GL, Nathan JA. Miles AL, et al. Among authors: nathan ja. Elife. 2017 Mar 15;6:e22693. doi: 10.7554/eLife.22693. Elife. 2017. PMID: 28296633 Free PMC article.

6

Myosin VI-Dependent Actin Cages Encapsulate Parkin-Positive Damaged Mitochondria.

Kruppa AJ, Kishi-Itakura C, Masters TA, Rorbach JE, Grice GL, Kendrick-Jones J, Nathan JA, Minczuk M, Buss F. Kruppa AJ, et al. Among authors: nathan ja. Dev Cell. 2018 Feb 26;44(4):484-499.e6. doi: 10.1016/j.devcel.2018.01.007. Epub 2018 Feb 1. Dev Cell. 2018. PMID: 29398621 Free PMC article.

7

ABHD11 maintains 2-oxoglutarate metabolism by preserving functional lipoylation of the 2-oxoglutarate dehydrogenase complex.

Bailey PSJ, Ortmann BM, Martinelli AW, Houghton JW, Costa ASH, Burr SP, Antrobus R, Frezza C, Nathan JA. Bailey PSJ, et al. Among authors: nathan ja. Nat Commun. 2020 Aug 13;11(1):4046. doi: 10.1038/s41467-020-17862-6. Nat Commun. 2020. PMID: 32792488 Free PMC article.

8

Selective Histone Deacetylase 6 Inhibitors Restore Cone Photoreceptor Vision or Outer Segment Morphology in Zebrafish and Mouse Models of Retinal Blindness.

Sundaramurthi H, Roche SL, Grice GL, Moran A, Dillion ET, Campiani G, Nathan JA, Kennedy BN. Sundaramurthi H, et al. Among authors: nathan ja. Front Cell Dev Biol. 2020 Aug 26;8:689. doi: 10.3389/fcell.2020.00689. eCollection 2020. Front Cell Dev Biol. 2020. PMID: 32984302 Free PMC article.

9

Quantitative proteomic analysis of SARS-CoV-2 infection of primary human airway ciliated cells and lung epithelial cells demonstrates the effectiveness of SARS-CoV-2 innate immune evasion.

Crozier TWM, Greenwood EJD, Williamson JC, Guo W, Porter LM, Gabaev I, Teixeira-Silva A, Grice GL, Wickenhagen A, Stanton RJ, Wang ECY, Wilson SJ, Matheson NJ, Nathan JA, McCaughan F, Lehner PJ. Crozier TWM, et al. Among authors: nathan ja. Wellcome Open Res. 2022 Sep 7;7:224. doi: 10.12688/wellcomeopenres.17946.1. eCollection 2022. Wellcome Open Res. 2022. PMID: 36483314 Free PMC article.

10

TMEM129 is a Derlin-1 associated ERAD E3 ligase essential for virus-induced degradation of MHC-I.

van den Boomen DJ, Timms RT, Grice GL, Stagg HR, Skødt K, Dougan G, Nathan JA, Lehner PJ. van den Boomen DJ, et al. Among authors: nathan ja. Proc Natl Acad Sci U S A. 2014 Aug 5;111(31):11425-30. doi: 10.1073/pnas.1409099111. Epub 2014 Jul 16. Proc Natl Acad Sci U S A. 2014. PMID: 25030448 Free PMC article.

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