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An antibiotic from an uncultured bacterium binds to an immutable target.
Shukla R, Peoples AJ, Ludwig KC, Maity S, Derks MGN, De Benedetti S, Krueger AM, Vermeulen BJA, Harbig T, Lavore F, Kumar R, Honorato RV, Grein F, Nieselt K, Liu Y, Bonvin AMJJ, Baldus M, Kubitscheck U, Breukink E, Achorn C, Nitti A, Schwalen CJ, Spoering AL, Ling LL, Hughes D, Lelli M, Roos WH, Lewis K, Schneider T, Weingarth M. Shukla R, et al. Among authors: schwalen cj. Cell. 2023 Sep 14;186(19):4059-4073.e27. doi: 10.1016/j.cell.2023.07.038. Epub 2023 Aug 22. Cell. 2023. PMID: 37611581 Free article.
A new antibiotic from an uncultured bacterium binds to an immutable target.
Shukla R, Peoples AJ, Ludwig KC, Maity S, Derks MGN, de Benedetti S, Krueger AM, Vermeulen BJA, Lavore F, Honorato RV, Grein F, Bonvin A, Kubitscheck U, Breukink E, Achorn C, Nitti A, Schwalen CJ, Spoering AL, Ling LL, Hughes D, Lelli M, Roos WH, Lewis K, Schneider T, Weingarth M. Shukla R, et al. Among authors: schwalen cj. bioRxiv [Preprint]. 2023 May 15:2023.05.15.540765. doi: 10.1101/2023.05.15.540765. bioRxiv. 2023. PMID: 37292624 Free PMC article. Updated. Preprint.
Correction to "Bioinformatic Mapping of Radical S-Adenosylmethionine-Dependent Ribosomally Synthesized and Post-Translationally Modified Peptides Identifies New Cα, Cβ, and Cγ-Linked Thioether-Containing Peptides".
Hudson GA, Burkhart BJ, DiCaprio AJ, Schwalen CJ, Kille B, Pogorelov TV, Mitchell DA. Hudson GA, et al. Among authors: schwalen cj. J Am Chem Soc. 2021 Jul 14;143(27):10479. doi: 10.1021/jacs.1c06285. Epub 2021 Jul 1. J Am Chem Soc. 2021. PMID: 34197098 No abstract available.
Bioinformatic Mapping of Radical S-Adenosylmethionine-Dependent Ribosomally Synthesized and Post-Translationally Modified Peptides Identifies New Cα, Cβ, and Cγ-Linked Thioether-Containing Peptides.
Hudson GA, Burkhart BJ, DiCaprio AJ, Schwalen CJ, Kille B, Pogorelov TV, Mitchell DA. Hudson GA, et al. Among authors: schwalen cj. J Am Chem Soc. 2019 May 22;141(20):8228-8238. doi: 10.1021/jacs.9b01519. Epub 2019 May 13. J Am Chem Soc. 2019. PMID: 31059252 Free PMC article.
antiSMASH 4.0-improvements in chemistry prediction and gene cluster boundary identification.
Blin K, Wolf T, Chevrette MG, Lu X, Schwalen CJ, Kautsar SA, Suarez Duran HG, de Los Santos ELC, Kim HU, Nave M, Dickschat JS, Mitchell DA, Shelest E, Breitling R, Takano E, Lee SY, Weber T, Medema MH. Blin K, et al. Among authors: schwalen cj. Nucleic Acids Res. 2017 Jul 3;45(W1):W36-W41. doi: 10.1093/nar/gkx319. Nucleic Acids Res. 2017. PMID: 28460038 Free PMC article.
Head-to-Head Prenyl Synthases in Pathogenic Bacteria.
Schwalen CJ, Feng X, Liu W, O-Dowd B, Ko TP, Shin CJ, Guo RT, Mitchell DA, Oldfield E. Schwalen CJ, et al. Chembiochem. 2017 Jun 1;18(11):985-991. doi: 10.1002/cbic.201700099. Epub 2017 Apr 25. Chembiochem. 2017. PMID: 28340291 Free PMC article.
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