Kirabo A - Search Results

1

Three-dimensional mitochondria reconstructions of murine cardiac muscle changes in size across aging.

Vue Z, Neikirk K, Vang L, Garza-Lopez E, Christensen TA, Shao J, Lam J, Beasley HK, Marshall AG, Crabtree A, Anudokem J Jr, Rodriguez B, Kirk B, Bacevac S, Barongan T, Shao B, Stephens DC, Kabugi K, Koh HJ, Koh A, Evans CS, Taylor B, Reddy AK, Miller-Fleming T, Actkins KV, Zaganjor E, Daneshgar N, Murray SA, Mobley BC, Damo SM, Gaddy JA, Riggs B, Wanjalla C, Kirabo A, McReynolds M, Gomez JA, Phillips MA, Exil V, Dai DF, Hinton A Jr. Vue Z, et al. Among authors: kirabo a. Am J Physiol Heart Circ Physiol. 2023 Nov 1;325(5):H965-H982. doi: 10.1152/ajpheart.00202.2023. Epub 2023 Aug 25. Am J Physiol Heart Circ Physiol. 2023. PMID: 37624101 Free PMC article.

2

Elevated levels of mast cells are involved in pruritus associated with polycythemia vera in JAK2V617F transgenic mice.

Jin X, Zhao W, Kirabo A, Park SO, Ho WT, Sayeski PP, Zhao ZJ. Jin X, et al. Among authors: kirabo a. J Immunol. 2014 Jul 15;193(2):477-84. doi: 10.4049/jimmunol.1301946. Epub 2014 Jun 11. J Immunol. 2014. PMID: 24920845

3

Identification of a novel inhibitor of JAK2 tyrosine kinase by structure-based virtual screening.

Kiss R, Polgár T, Kirabo A, Sayyah J, Figueroa NC, List AF, Sokol L, Zuckerman KS, Gali M, Bisht KS, Sayeski PP, Keseru GM. Kiss R, et al. Among authors: kirabo a. Bioorg Med Chem Lett. 2009 Jul 1;19(13):3598-601. doi: 10.1016/j.bmcl.2009.04.138. Epub 2009 May 5. Bioorg Med Chem Lett. 2009. PMID: 19447617 Free PMC article.

4

Vascular smooth muscle Jak2 deletion prevents angiotensin II-mediated neointima formation following injury in mice.

Kirabo A, Oh SP, Kasahara H, Wagner KU, Sayeski PP. Kirabo A, et al. J Mol Cell Cardiol. 2011 Jun;50(6):1026-34. doi: 10.1016/j.yjmcc.2011.03.005. Epub 2011 Mar 17. J Mol Cell Cardiol. 2011. PMID: 21420414 Free PMC article.

5

A46, a benzothiophene-derived compound, suppresses Jak2-mediated pathologic cell growth.

Majumder A, Magis AT, Park SO, Figueroa NC, Baskin R, Kirabo A, Allan RW, Zhao ZJ, Bisht KS, Keseru GM, Sayeski PP. Majumder A, et al. Among authors: kirabo a. Exp Hematol. 2012 Jan;40(1):22-34. doi: 10.1016/j.exphem.2011.10.003. Epub 2011 Oct 20. Exp Hematol. 2012. PMID: 22019628 Free PMC article.

6

HIV-positive demonstrate more salt sensitivity and nocturnal non-dipping blood pressure than HIV-negative individuals.

Masenga SK, Kirabo A, Hamooya BM, Nzala S, Kwenda G, Heimburger DC, Mutale W, Koethe JR, Pilic L, Munsaka SM. Masenga SK, et al. Among authors: kirabo a. Clin Hypertens. 2021 Jan 15;27(1):2. doi: 10.1186/s40885-020-00160-0. Clin Hypertens. 2021. PMID: 33446278 Free PMC article.

7

The small molecule inhibitor G6 significantly reduces bone marrow fibrosis and the mutant burden in a mouse model of Jak2-mediated myelofibrosis.

Kirabo A, Park SO, Wamsley HL, Gali M, Baskin R, Reinhard MK, Zhao ZJ, Bisht KS, Keserű GM, Cogle CR, Sayeski PP. Kirabo A, et al. Am J Pathol. 2012 Sep;181(3):858-65. doi: 10.1016/j.ajpath.2012.05.033. Epub 2012 Jul 13. Am J Pathol. 2012. PMID: 22796437 Free PMC article.

8

The stilbenoid tyrosine kinase inhibitor, G6, suppresses Jak2-V617F-mediated human pathological cell growth in vitro and in vivo.

Kirabo A, Embury J, Kiss R, Polgár T, Gali M, Majumder A, Bisht KS, Cogle CR, Keseru GM, Sayeski PP. Kirabo A, et al. J Biol Chem. 2011 Feb 11;286(6):4280-91. doi: 10.1074/jbc.M110.200774. Epub 2010 Dec 2. J Biol Chem. 2011. PMID: 21127060 Free PMC article.

9

Immune activation caused by vascular oxidation promotes fibrosis and hypertension.

Wu J, Saleh MA, Kirabo A, Itani HA, Montaniel KR, Xiao L, Chen W, Mernaugh RL, Cai H, Bernstein KE, Goronzy JJ, Weyand CM, Curci JA, Barbaro NR, Moreno H, Davies SS, Roberts LJ 2nd, Madhur MS, Harrison DG. Wu J, et al. Among authors: kirabo a. J Clin Invest. 2016 Jan;126(1):50-67. doi: 10.1172/JCI80761. Epub 2015 Nov 23. J Clin Invest. 2016. PMID: 26595812 Free PMC article.

10

The Jak2 inhibitor, G6, alleviates Jak2-V617F-mediated myeloproliferative neoplasia by providing significant therapeutic efficacy to the bone marrow.

Kirabo A, Park SO, Majumder A, Gali M, Reinhard MK, Wamsley HL, Zhao ZJ, Cogle CR, Bisht KS, Keserü GM, Sayeski PP. Kirabo A, et al. Neoplasia. 2011 Nov;13(11):1058-68. doi: 10.1593/neo.111112. Neoplasia. 2011. PMID: 22131881 Free PMC article.

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