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Sustained CD28 costimulation is required for self-renewal and differentiation of TCF-1+ PD-1+ CD8 T cells.
Humblin E, Korpas I, Lu J, Filipescu D, van der Heide V, Goldstein S, Vaidya A, Soares-Schanoski A, Casati B, Selvan ME, Gümüş ZH, Wieland A, Corrado M, Cohen-Gould L, Bernstein E, Homann D, Chipuk J, Kamphorst AO. Humblin E, et al. Among authors: bernstein e. Sci Immunol. 2023 Aug 4;8(86):eadg0878. doi: 10.1126/sciimmunol.adg0878. Epub 2023 Aug 25. Sci Immunol. 2023. PMID: 37624910 Free PMC article.
Solid tumours hijack the histone variant network.
Ghiraldini FG, Filipescu D, Bernstein E. Ghiraldini FG, et al. Among authors: bernstein e. Nat Rev Cancer. 2021 Apr;21(4):257-275. doi: 10.1038/s41568-020-00330-0. Epub 2021 Feb 10. Nat Rev Cancer. 2021. PMID: 33568791 Free PMC article. Review.
MacroH2A restricts inflammatory gene expression in melanoma cancer-associated fibroblasts by coordinating chromatin looping.
Filipescu D, Carcamo S, Agarwal A, Tung N, Humblin É, Goldberg MS, Vyas NS, Beaumont KG, Demircioglu D, Sridhar S, Ghiraldini FG, Capparelli C, Aplin AE, Salmon H, Sebra R, Kamphorst AO, Merad M, Hasson D, Bernstein E. Filipescu D, et al. Among authors: bernstein e. Nat Cell Biol. 2023 Sep;25(9):1332-1345. doi: 10.1038/s41556-023-01208-7. Epub 2023 Aug 21. Nat Cell Biol. 2023. PMID: 37605008 Free PMC article.
Harnessing BET Inhibitor Sensitivity Reveals AMIGO2 as a Melanoma Survival Gene.
Fontanals-Cirera B, Hasson D, Vardabasso C, Di Micco R, Agrawal P, Chowdhury A, Gantz M, de Pablos-Aragoneses A, Morgenstern A, Wu P, Filipescu D, Valle-Garcia D, Darvishian F, Roe JS, Davies MA, Vakoc CR, Hernando E, Bernstein E. Fontanals-Cirera B, et al. Among authors: bernstein e. Mol Cell. 2017 Nov 16;68(4):731-744.e9. doi: 10.1016/j.molcel.2017.11.004. Mol Cell. 2017. PMID: 29149598 Free PMC article.
Altered BAF occupancy and transcription factor dynamics in PBAF-deficient melanoma.
Carcamo S, Nguyen CB, Grossi E, Filipescu D, Alpsoy A, Dhiman A, Sun D, Narang S, Imig J, Martin TC, Parsons R, Aifantis I, Tsirigos A, Aguirre-Ghiso JA, Dykhuizen EC, Hasson D, Bernstein E. Carcamo S, et al. Among authors: bernstein e. Cell Rep. 2022 Apr 5;39(1):110637. doi: 10.1016/j.celrep.2022.110637. Cell Rep. 2022. PMID: 35385731 Free PMC article.
A local tumor microenvironment acquired super-enhancer induces an oncogenic driver in colorectal carcinoma.
Zhou RW, Xu J, Martin TC, Zachem AL, He J, Ozturk S, Demircioglu D, Bansal A, Trotta AP, Giotti B, Gryder B, Shen Y, Wu X, Carcamo S, Bosch K, Hopkins B, Tsankov A, Steinhagen R, Jones DR, Asara J, Chipuk JE, Brody R, Itzkowitz S, Chio IIC, Hasson D, Bernstein E, Parsons RE. Zhou RW, et al. Among authors: bernstein e. Nat Commun. 2022 Oct 17;13(1):6041. doi: 10.1038/s41467-022-33377-8. Nat Commun. 2022. PMID: 36253360 Free PMC article.
Author Correction: A local tumor microenvironment acquired super-enhancer induces an oncogenic driver in colorectal carcinoma.
Zhou RW, Xu J, Martin TC, Zachem AL, He J, Ozturk S, Demircioglu D, Bansal A, Trotta AP, Giotti B, Gryder B, Shen Y, Wu X, Carcamo S, Bosch K, Hopkins B, Tsankov A, Steinhagen R, Jones DR, Asara J, Chipuk JE, Brody R, Itzkowitz S, Chio IIC, Hasson D, Bernstein E, Parsons RE. Zhou RW, et al. Among authors: bernstein e. Nat Commun. 2023 Apr 6;14(1):1923. doi: 10.1038/s41467-023-37640-4. Nat Commun. 2023. PMID: 37024505 Free PMC article. No abstract available.
939 results