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A novel molecular class that recruits HDAC/MECP2 complexes to PU.1 motifs reduces neuroinflammation.
Ralvenius WT, Mungenast AE, Woolf H, Huston MM, Gillingham TZ, Godin SK, Penney J, Cam HP, Gao F, Fernandez CG, Czako B, Lightfoot Y, Ray WJ, Beckmann A, Goate AM, Marcora E, Romero-Molina C, Ayata P, Schaefer A, Gjoneska E, Tsai LH. Ralvenius WT, et al. Among authors: lightfoot y. J Exp Med. 2023 Nov 6;220(11):e20222105. doi: 10.1084/jem.20222105. Epub 2023 Aug 29. J Exp Med. 2023. PMID: 37642942 Free PMC article.
Immunity to commensal skin fungi promotes psoriasiform skin inflammation.
Hurabielle C, Link VM, Bouladoux N, Han SJ, Merrill ED, Lightfoot YL, Seto N, Bleck CKE, Smelkinson M, Harrison OJ, Linehan JL, Tamoutounour S, Lionakis MS, Kaplan MJ, Nakajima S, Belkaid Y. Hurabielle C, et al. Among authors: lightfoot yl. Proc Natl Acad Sci U S A. 2020 Jul 14;117(28):16465-16474. doi: 10.1073/pnas.2003022117. Epub 2020 Jun 29. Proc Natl Acad Sci U S A. 2020. PMID: 32601220 Free PMC article.
Peptidylarginine deiminases 2 and 4 modulate innate and adaptive immune responses in TLR-7-dependent lupus.
Liu Y, Lightfoot YL, Seto N, Carmona-Rivera C, Moore E, Goel R, O'Neil L, Mistry P, Hoffmann V, Mondal S, Premnath PN, Gribbons K, Dell'Orso S, Jiang K, Thompson PR, Sun HW, Coonrod SA, Kaplan MJ. Liu Y, et al. Among authors: lightfoot yl. JCI Insight. 2018 Dec 6;3(23):e124729. doi: 10.1172/jci.insight.124729. JCI Insight. 2018. PMID: 30518690 Free PMC article.
Metabolic pathways and immunometabolism in rare kidney diseases.
Grayson PC, Eddy S, Taroni JN, Lightfoot YL, Mariani L, Parikh H, Lindenmeyer MT, Ju W, Greene CS, Godfrey B, Cohen CD, Krischer J, Kretzler M, Merkel PA; Vasculitis Clinical Research Consortium, the European Renal cDNA Bank cohort, and the Nephrotic Syndrome Study Network. Grayson PC, et al. Among authors: lightfoot yl. Ann Rheum Dis. 2018 Aug;77(8):1226-1233. doi: 10.1136/annrheumdis-2017-212935. Epub 2018 May 3. Ann Rheum Dis. 2018. PMID: 29724730 Free PMC article.
Metabolic abnormalities and oxidative stress in lupus.
Lightfoot YL, Blanco LP, Kaplan MJ. Lightfoot YL, et al. Curr Opin Rheumatol. 2017 Sep;29(5):442-449. doi: 10.1097/BOR.0000000000000413. Curr Opin Rheumatol. 2017. PMID: 28639951 Free PMC article. Review.
23 results