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Grp78 is required for intestinal Kras-dependent glycolysis proliferation and adenomagenesis.
Spaan CN, de Boer RJ, Smit WL, van der Meer JH, van Roest M, Vermeulen JL, Koelink PJ, Becker MA, Go S, Silva J, Faller WJ, van den Brink GR, Muncan V, Heijmans J. Spaan CN, et al. Among authors: silva j. Life Sci Alliance. 2023 Aug 29;6(11):e202301912. doi: 10.26508/lsa.202301912. Print 2023 Nov. Life Sci Alliance. 2023. PMID: 37643866 Free PMC article.
Early Life Antibiotics Influence In Vivo and In Vitro Mouse Intestinal Epithelium Maturation and Functioning.
Garcia TM, van Roest M, Vermeulen JLM, Meisner S, Smit WL, Silva J, Koelink PJ, Koster J, Faller WJ, Wildenberg ME, van Elburg RM, Muncan V, Renes IB. Garcia TM, et al. Among authors: silva j. Cell Mol Gastroenterol Hepatol. 2021;12(3):943-981. doi: 10.1016/j.jcmgh.2021.05.019. Epub 2021 Jun 6. Cell Mol Gastroenterol Hepatol. 2021. PMID: 34102314 Free PMC article.
Identifying ribosome heterogeneity using ribosome profiling.
Alkan F, Wilkins OG, Hernández-Pérez S, Ramalho S, Silva J, Ule J, Faller WJ. Alkan F, et al. Among authors: silva j. Nucleic Acids Res. 2022 Sep 9;50(16):e95. doi: 10.1093/nar/gkac484. Nucleic Acids Res. 2022. PMID: 35687114 Free PMC article.
Ribosome impairment regulates intestinal stem cell identity via ZAKɑ activation.
Silva J, Alkan F, Ramalho S, Snieckute G, Prekovic S, Garcia AK, Hernández-Pérez S, van der Kammen R, Barnum D, Hoekman L, Altelaar M, Zwart W, Suijkerbuijk SJE, Bekker-Jensen S, Faller WJ. Silva J, et al. Nat Commun. 2022 Aug 2;13(1):4492. doi: 10.1038/s41467-022-32220-4. Nat Commun. 2022. PMID: 35918345 Free PMC article.
The histone methyltransferase SETD2 negatively regulates cell size.
Molenaar TM, Malik M, Silva J, Liu NQ, Haarhuis JHI, Ambrosi C, Kwesi-Maliepaard EM, van Welsem T, Baubec T, Faller WJ, van Leeuwen F. Molenaar TM, et al. Among authors: silva j. J Cell Sci. 2022 Oct 1;135(19):jcs259856. doi: 10.1242/jcs.259856. Epub 2022 Oct 6. J Cell Sci. 2022. PMID: 36052643 Free PMC article.
Glucocorticoid receptor triggers a reversible drug-tolerant dormancy state with acquired therapeutic vulnerabilities in lung cancer.
Prekovic S, Schuurman K, Mayayo-Peralta I, Manjón AG, Buijs M, Yavuz S, Wellenstein MD, Barrera A, Monkhorst K, Huber A, Morris B, Lieftink C, Chalkiadakis T, Alkan F, Silva J, Győrffy B, Hoekman L, van den Broek B, Teunissen H, Debets DO, Severson T, Jonkers J, Reddy T, de Visser KE, Faller W, Beijersbergen R, Altelaar M, de Wit E, Medema R, Zwart W. Prekovic S, et al. Among authors: silva j. Nat Commun. 2021 Jul 16;12(1):4360. doi: 10.1038/s41467-021-24537-3. Nat Commun. 2021. PMID: 34272384 Free PMC article.
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