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The ASSESS-AKI Study found urinary epidermal growth factor is associated with reduced risk of major adverse kidney events.
Menez S, Wen Y, Xu L, Moledina DG, Thiessen-Philbrook H, Hu D, Obeid W, Bhatraju PK, Ikizler TA, Siew ED, Chinchilli VM, Garg AX, Go AS, Liu KD, Kaufman JS, Kimmel PL, Himmelfarb J, Coca SG, Cantley LG, Parikh CR. Menez S, et al. Among authors: cantley lg. Kidney Int. 2023 Dec;104(6):1194-1205. doi: 10.1016/j.kint.2023.08.007. Epub 2023 Aug 29. Kidney Int. 2023. PMID: 37652206 Free article.
Multi-Scalar Data Integration Links Glomerular Angiopoietin-Tie Signaling Pathway Activation With Progression of Diabetic Kidney Disease.
Liu J, Nair V, Zhao YY, Chang DY, Limonte C, Bansal N, Fermin D, Eichinger F, Tanner EC, Bellovich KA, Steigerwalt S, Bhat Z, Hawkins JJ, Subramanian L, Rosas SE, Sedor JR, Vasquez MA, Waikar SS, Bitzer M, Pennathur S, Brosius FC, De Boer I, Chen M, Kretzler M, Ju W; Kidney Precision Medicine Project and Michigan Translational Core C-PROBE Investigator Group; Kidney Precision Medicine Project and Michigan Translational Core C-PROBE Investigator Group. Liu J, et al. Diabetes. 2022 Dec 1;71(12):2664-2676. doi: 10.2337/db22-0169. Diabetes. 2022. PMID: 36331122 Free PMC article.
Longitudinal biomarkers and kidney disease progression after acute kidney injury.
Wen Y, Xu L, Melchinger I, Thiessen-Philbrook H, Moledina DG, Coca SG, Hsu CY, Go AS, Liu KD, Siew ED, Ikizler TA, Chinchilli VM, Kaufman JS, Kimmel PL, Himmelfarb J, Cantley LG, Parikh CR; ASSESS-AKI Consortium. Wen Y, et al. Among authors: cantley lg. JCI Insight. 2023 May 8;8(9):e167731. doi: 10.1172/jci.insight.167731. JCI Insight. 2023. PMID: 36951957 Free PMC article.
Identification and validation of urinary CXCL9 as a biomarker for diagnosis of acute interstitial nephritis.
Moledina DG, Obeid W, Smith RN, Rosales I, Sise ME, Moeckel G, Kashgarian M, Kuperman M, Campbell KN, Lefferts S, Meliambro K, Bitzer M, Perazella MA, Luciano RL, Pober JS, Cantley LG, Colvin RB, Wilson FP, Parikh CR. Moledina DG, et al. Among authors: cantley lg. J Clin Invest. 2023 Jul 3;133(13):e168950. doi: 10.1172/JCI168950. J Clin Invest. 2023. PMID: 37395276 Free PMC article.
Analysis of the human kidney transcriptome and plasma proteome identifies markers of proximal tubule maladaptation to injury.
Wen Y, Su E, Xu L, Menez S, Moledina DG, Obeid W, Palevsky PM, Mansour SG, Devarajan P, Cantley LG, Cahan P, Parikh CR; Kidney Precision Medicine Project; Translational Investigation of Biomarker Endpoint of Acute Kidney Injury. Wen Y, et al. Among authors: cantley lg. Sci Transl Med. 2023 Dec 13;15(726):eade7287. doi: 10.1126/scitranslmed.ade7287. Epub 2023 Dec 13. Sci Transl Med. 2023. PMID: 38091407
The chromatin landscape of healthy and injured cell types in the human kidney.
Gisch DL, Brennan M, Lake BB, Basta J, Keller MS, Melo Ferreira R, Akilesh S, Ghag R, Lu C, Cheng YH, Collins KS, Parikh SV, Rovin BH, Robbins L, Stout L, Conklin KY, Diep D, Zhang B, Knoten A, Barwinska D, Asghari M, Sabo AR, Ferkowicz MJ, Sutton TA, Kelly KJ, De Boer IH, Rosas SE, Kiryluk K, Hodgin JB, Alakwaa F, Winfree S, Jefferson N, Türkmen A, Gaut JP, Gehlenborg N, Phillips CL, El-Achkar TM, Dagher PC, Hato T, Zhang K, Himmelfarb J, Kretzler M, Mollah S; Kidney Precision Medicine Project (KPMP); Jain S, Rauchman M, Eadon MT. Gisch DL, et al. Nat Commun. 2024 Jan 10;15(1):433. doi: 10.1038/s41467-023-44467-6. Nat Commun. 2024. PMID: 38199997 Free PMC article.
Identification and validation of urinary CXCL9 as a biomarker for diagnosis of acute interstitial nephritis.
Moledina DG, Obeid W, Smith RN, Rosales I, Sise ME, Moeckel G, Kashgarian M, Kuperman M, Campbell KN, Lefferts S, Meliambro K, Bitzer M, Perazella MA, Luciano RL, Pober JS, Cantley LG, Colvin RB, Wilson FP, Parikh CR. Moledina DG, et al. Among authors: cantley lg. J Clin Invest. 2024 Mar 15;134(6):e180583. doi: 10.1172/JCI180583. J Clin Invest. 2024. PMID: 38488004 Free PMC article. No abstract available.
Rationale and Design of a Phase 2, Double-blind, Placebo-Controlled, Randomized Trial Evaluating AMP Kinase-Activation by Metformin in Focal Segmental Glomerulosclerosis.
Barsotti GC, Luciano R, Kumar A, Meliambro K, Kakade V, Tokita J, Naik A, Fu J, Peck E, Pell J, Reghuvaran A, Tanvir EM, Patel P, Zhang W, Li F, Moeckel G, Perincheri S, Cantley L, Moledina DG, Wilson FP, He JC, Menon MC. Barsotti GC, et al. Kidney Int Rep. 2024 Feb 13;9(5):1354-1368. doi: 10.1016/j.ekir.2024.02.006. eCollection 2024 May. Kidney Int Rep. 2024. PMID: 38707807 Free PMC article.
The Lymphatic System in Kidney Disease.
Baker ML, Cantley LG. Baker ML, et al. Among authors: cantley lg. Kidney360. 2023 Jun 1;4(6):e841-e850. doi: 10.34067/KID.0000000000000120. Epub 2023 Apr 5. Kidney360. 2023. PMID: 37019177 Free PMC article.
112 results