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Identification of potent and selective N-myristoyltransferase inhibitors of Plasmodium vivax liver stage hypnozoites and schizonts.
Rodríguez-Hernández D, Vijayan K, Zigweid R, Fenwick MK, Sankaran B, Roobsoong W, Sattabongkot J, Glennon EKK, Myler PJ, Sunnerhagen P, Staker BL, Kaushansky A, Grøtli M. Rodríguez-Hernández D, et al. Among authors: glennon ekk. Nat Commun. 2023 Sep 5;14(1):5408. doi: 10.1038/s41467-023-41119-7. Nat Commun. 2023. PMID: 37669940 Free PMC article.
Opportunities for Host-targeted Therapies for Malaria.
Glennon EKK, Dankwa S, Smith JD, Kaushansky A. Glennon EKK, et al. Trends Parasitol. 2018 Oct;34(10):843-860. doi: 10.1016/j.pt.2018.07.011. Epub 2018 Aug 16. Trends Parasitol. 2018. PMID: 30122551 Free PMC article. Review.
Liver stage malaria infection is controlled by host regulators of lipid peroxidation.
Kain HS, Glennon EKK, Vijayan K, Arang N, Douglass AN, Fortin CL, Zuck M, Lewis AJ, Whiteside SL, Dudgeon DR, Johnson JS, Aderem A, Stevens KR, Kaushansky A. Kain HS, et al. Among authors: glennon ekk. Cell Death Differ. 2020 Jan;27(1):44-54. doi: 10.1038/s41418-019-0338-1. Epub 2019 May 7. Cell Death Differ. 2020. PMID: 31065106 Free PMC article.
Host-targeted Interventions as an Exciting Opportunity to Combat Malaria.
Vijayan K, Wei L, Glennon EKK, Mattocks C, Bourgeois N, Staker B, Kaushansky A. Vijayan K, et al. Among authors: glennon ekk. Chem Rev. 2021 Sep 8;121(17):10452-10468. doi: 10.1021/acs.chemrev.1c00062. Epub 2021 Jul 1. Chem Rev. 2021. PMID: 34197083 Review.
Antibody interference by a non-neutralizing antibody abrogates humoral protection against Plasmodium yoelii liver stage.
Vijayan K, Visweswaran GRR, Chandrasekaran R, Trakhimets O, Brown SL, Watson A, Zuck M, Dambrauskas N, Raappana A, Carbonetti S, Kelnhofer-Millevolte L, Glennon EKK, Postiglione R, Sather DN, Kaushansky A. Vijayan K, et al. Among authors: glennon ekk. Cell Rep. 2021 Aug 3;36(5):109489. doi: 10.1016/j.celrep.2021.109489. Cell Rep. 2021. PMID: 34348141 Free article.
16 results