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A Type II-B Cas9 nuclease with minimized off-targets and reduced chromosomal translocations in vivo.
Bestas B, Wimberger S, Degtev D, Madsen A, Rottner AK, Karlsson F, Naumenko S, Callahan M, Touza JL, Francescatto M, Möller CI, Badertscher L, Li S, Cerboni S, Selfjord N, Ericson E, Gordon E, Firth M, Chylinski K, Taheri-Ghahfarokhi A, Bohlooly-Y M, Snowden M, Pangalos M, Nuttall B, Akcakaya P, Sienski G, Maresca M. Bestas B, et al. Among authors: badertscher l. Nat Commun. 2023 Sep 6;14(1):5474. doi: 10.1038/s41467-023-41240-7. Nat Commun. 2023. PMID: 37673883 Free PMC article.
Creating Designer Engineered Extracellular Vesicles for Diverse Ligand Display, Target Recognition, and Controlled Protein Loading and Delivery.
Ivanova A, Badertscher L, O'Driscoll G, Bergman J, Gordon E, Gunnarsson A, Johansson C, Munson MJ, Spinelli C, Torstensson S, Vilén L, Voirel A, Wiseman J, Rak J, Dekker N, Lázaro-Ibáñez E. Ivanova A, et al. Among authors: badertscher l. Adv Sci (Weinh). 2023 Dec;10(34):e2304389. doi: 10.1002/advs.202304389. Epub 2023 Oct 22. Adv Sci (Weinh). 2023. PMID: 37867228 Free PMC article.
Genetic dependencies associated with transcription factor activities in human cancer cell lines.
Thatikonda V, Supper V, Wachter J, Kaya O, Kombara A, Bilgilier C, Ravichandran MC, Lipp JJ, Sharma R, Badertscher L, Boghossian AS, Rees MG, Ronan MM, Roth JA, Grosche S, Neumüller RA, Mair B, Mauri F, Popa A. Thatikonda V, et al. Among authors: badertscher l. Cell Rep. 2024 May 28;43(5):114175. doi: 10.1016/j.celrep.2024.114175. Epub 2024 Apr 30. Cell Rep. 2024. PMID: 38691456 Free article.
Development of an ObLiGaRe Doxycycline Inducible Cas9 system for pre-clinical cancer drug discovery.
Lundin A, Porritt MJ, Jaiswal H, Seeliger F, Johansson C, Bidar AW, Badertscher L, Wimberger S, Davies EJ, Hardaker E, Martins CP, James E, Admyre T, Taheri-Ghahfarokhi A, Bradley J, Schantz A, Alaeimahabadi B, Clausen M, Xu X, Mayr LM, Nitsch R, Bohlooly-Y M, Barry ST, Maresca M. Lundin A, et al. Among authors: badertscher l. Nat Commun. 2020 Sep 29;11(1):4903. doi: 10.1038/s41467-020-18548-9. Nat Commun. 2020. PMID: 32994412 Free PMC article.
[Initial management of febrile neutropenia].
Badertscher L, Damak H, Mercier L, Décosterd D. Badertscher L, et al. Rev Med Suisse. 2016 Aug 10;12(526):1321-1325. Rev Med Suisse. 2016. PMID: 28671776 French.
13 results