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Preexisting tumor-resident T cells with cytotoxic potential associate with response to neoadjuvant anti-PD-1 in head and neck cancer.
Oliveira G, Egloff AM, Afeyan AB, Wolff JO, Zeng Z, Chernock RD, Zhou L, Messier C, Lizotte P, Pfaff KL, Stromhaug K, Penter L, Haddad RI, Hanna GJ, Schoenfeld JD, Goguen LA, Annino DJ, Jo V, Oppelt P, Pipkorn P, Jackson R, Puram SV, Paniello RC, Rich JT, Webb J, Zevallos JP, Mansour M, Fu J, Dunn GP, Rodig SJ, Ley J, Morris LGT, Dunn L, Paweletz CP, Kallogjeri D, Piccirillo JF, Adkins DR, Wu CJ, Uppaluri R. Oliveira G, et al. Among authors: fu j. Sci Immunol. 2023 Sep 8;8(87):eadf4968. doi: 10.1126/sciimmunol.adf4968. Epub 2023 Sep 8. Sci Immunol. 2023. PMID: 37683037 Free PMC article.
Therapeutically Increasing MHC-I Expression Potentiates Immune Checkpoint Blockade.
Gu SS, Zhang W, Wang X, Jiang P, Traugh N, Li Z, Meyer C, Stewig B, Xie Y, Bu X, Manos MP, Font-Tello A, Gjini E, Lako A, Lim K, Conway J, Tewari AK, Zeng Z, Sahu AD, Tokheim C, Weirather JL, Fu J, Zhang Y, Kroger B, Liang JH, Cejas P, Freeman GJ, Rodig S, Long HW, Gewurz BE, Hodi FS, Brown M, Liu XS. Gu SS, et al. Among authors: fu j. Cancer Discov. 2021 Jun;11(6):1524-1541. doi: 10.1158/2159-8290.CD-20-0812. Epub 2021 Feb 15. Cancer Discov. 2021. PMID: 33589424 Free PMC article.
Molecular and cellular features of CTLA-4 blockade for relapsed myeloid malignancies after transplantation.
Penter L, Zhang Y, Savell A, Huang T, Cieri N, Thrash EM, Kim-Schulze S, Jhaveri A, Fu J, Ranasinghe S, Li S, Zhang W, Hathaway ES, Nazzaro M, Kim HT, Chen H, Thurin M, Rodig SJ, Severgnini M, Cibulskis C, Gabriel S, Livak KJ, Cutler C, Antin JH, Nikiforow S, Koreth J, Ho VT, Armand P, Ritz J, Streicher H, Neuberg D, Hodi FS, Gnjatic S, Soiffer RJ, Liu XS, Davids MS, Bachireddy P, Wu CJ. Penter L, et al. Among authors: fu j. Blood. 2021 Jun 10;137(23):3212-3217. doi: 10.1182/blood.2021010867. Blood. 2021. PMID: 33720354 Free PMC article. Clinical Trial.
TISMO: syngeneic mouse tumor database to model tumor immunity and immunotherapy response.
Zeng Z, Wong CJ, Yang L, Ouardaoui N, Li D, Zhang W, Gu S, Zhang Y, Liu Y, Wang X, Fu J, Zhou L, Zhang B, Kim S, Yates KB, Brown M, Freeman GJ, Uppaluri R, Manguso R, Liu XS. Zeng Z, et al. Among authors: fu j. Nucleic Acids Res. 2022 Jan 7;50(D1):D1391-D1397. doi: 10.1093/nar/gkab804. Nucleic Acids Res. 2022. PMID: 34534350 Free PMC article.
Checkpoint blockade-induced CD8+ T cell differentiation in head and neck cancer responders.
Zhou L, Zeng Z, Egloff AM, Zhang F, Guo F, Campbell KM, Du P, Fu J, Zolkind P, Ma X, Zhang Z, Zhang Y, Wang X, Gu S, Riley R, Nakahori Y, Keegan J, Haddad R, Schoenfeld JD, Griffith O, Manguso RT, Lederer JA, Liu XS, Uppaluri R. Zhou L, et al. Among authors: fu j. J Immunother Cancer. 2022 Jan;10(1):e004034. doi: 10.1136/jitc-2021-004034. J Immunother Cancer. 2022. PMID: 35058328 Free PMC article.
Inhibition of MAN2A1 Enhances the Immune Response to Anti-PD-L1 in Human Tumors.
Shi S, Gu S, Han T, Zhang W, Huang L, Li Z, Pan D, Fu J, Ge J, Brown M, Zhang P, Jiang P, Wucherpfennig KW, Liu XS. Shi S, et al. Among authors: fu j. Clin Cancer Res. 2020 Nov 15;26(22):5990-6002. doi: 10.1158/1078-0432.CCR-20-0778. Epub 2020 Jul 28. Clin Cancer Res. 2020. PMID: 32723834 Free PMC article.
Discovery of Targets for Immune-Metabolic Antitumor Drugs Identifies Estrogen-Related Receptor Alpha.
Sahu A, Wang X, Munson P, Klomp JPG, Wang X, Gu SS, Han Y, Qian G, Nicol P, Zeng Z, Wang C, Tokheim C, Zhang W, Fu J, Wang J, Nair NU, Rens JAP, Bourajjaj M, Jansen B, Leenders I, Lemmers J, Musters M, van Zanten S, van Zelst L, Worthington J, Liu JS, Juric D, Meyer CA, Oubrie A, Liu XS, Fisher DE, Flaherty KT. Sahu A, et al. Among authors: fu j. Cancer Discov. 2023 Mar 1;13(3):672-701. doi: 10.1158/2159-8290.CD-22-0244. Cancer Discov. 2023. PMID: 36745048 Free PMC article.
TIMER2.0 for analysis of tumor-infiltrating immune cells.
Li T, Fu J, Zeng Z, Cohen D, Li J, Chen Q, Li B, Liu XS. Li T, et al. Among authors: fu j. Nucleic Acids Res. 2020 Jul 2;48(W1):W509-W514. doi: 10.1093/nar/gkaa407. Nucleic Acids Res. 2020. PMID: 32442275 Free PMC article.
Immune receptor repertoires in pediatric and adult acute myeloid leukemia.
Zhang J, Hu X, Wang J, Sahu AD, Cohen D, Song L, Ouyang Z, Fan J, Wang B, Fu J, Gu S, Sade-Feldman M, Hacohen N, Li W, Ying X, Li B, Liu XS. Zhang J, et al. Among authors: fu j. Genome Med. 2019 Nov 26;11(1):73. doi: 10.1186/s13073-019-0681-3. Genome Med. 2019. PMID: 31771646 Free PMC article.
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