Holzbaur ELF - Search Results

1

Damaged mitochondria recruit the effector NEMO to activate NF-κB signaling.

Harding O, Holzer E, Riley JF, Martens S, Holzbaur ELF. Harding O, et al. Among authors: holzbaur elf. Mol Cell. 2023 Sep 7;83(17):3188-3204.e7. doi: 10.1016/j.molcel.2023.08.005. Mol Cell. 2023. PMID: 37683611 Free article.

2

Dynamic recruitment and activation of ALS-associated TBK1 with its target optineurin are required for efficient mitophagy.

Moore AS, Holzbaur EL. Moore AS, et al. Proc Natl Acad Sci U S A. 2016 Jun 14;113(24):E3349-58. doi: 10.1073/pnas.1523810113. Epub 2016 May 31. Proc Natl Acad Sci U S A. 2016. PMID: 27247382 Free PMC article.

3

ALS- and FTD-associated missense mutations in TBK1 differentially disrupt mitophagy.

Harding O, Evans CS, Ye J, Cheung J, Maniatis T, Holzbaur ELF. Harding O, et al. Among authors: holzbaur elf. Proc Natl Acad Sci U S A. 2021 Jun 15;118(24):e2025053118. doi: 10.1073/pnas.2025053118. Proc Natl Acad Sci U S A. 2021. PMID: 34099552 Free PMC article.

4

Structural basis for membrane recruitment of ATG16L1 by WIPI2 in autophagy.

Strong LM, Chang C, Riley JF, Boecker CA, Flower TG, Buffalo CZ, Ren X, Stavoe AK, Holzbaur EL, Hurley JH. Strong LM, et al. Elife. 2021 Sep 10;10:e70372. doi: 10.7554/eLife.70372. Elife. 2021. PMID: 34505572 Free PMC article.

5

The selective autophagy adaptor p62/SQSTM1 forms phase condensates regulated by HSP27 that facilitate the clearance of damaged lysosomes via lysophagy.

Gallagher ER, Holzbaur ELF. Gallagher ER, et al. Among authors: holzbaur elf. Cell Rep. 2023 Feb 28;42(2):112037. doi: 10.1016/j.celrep.2023.112037. Epub 2023 Jan 25. Cell Rep. 2023. PMID: 36701233 Free PMC article.

6

RAB3 phosphorylation by pathogenic LRRK2 impairs trafficking of synaptic vesicle precursors.

Dou D, Aiken J, Holzbaur ELF. Dou D, et al. Among authors: holzbaur elf. J Cell Biol. 2024 Jun 3;223(6):e202307092. doi: 10.1083/jcb.202307092. Epub 2024 Mar 21. J Cell Biol. 2024. PMID: 38512027 Free PMC article.

7

A RAB7A phosphoswitch coordinates Rubicon Homology protein regulation of Parkin-dependent mitophagy.

Tudorica DA, Basak B, Puerta Cordova AS, Khuu G, Rose K, Lazarou M, Holzbaur ELF, Hurley JH. Tudorica DA, et al. Among authors: holzbaur elf. J Cell Biol. 2024 Jul 1;223(7):e202309015. doi: 10.1083/jcb.202309015. Epub 2024 May 10. J Cell Biol. 2024. PMID: 38728007 Free PMC article.

8

Myosin learns to recruit AMPA receptors.

Perlson E, Holzbaur EL. Perlson E, et al. Cell. 2008 Oct 31;135(3):414-5. doi: 10.1016/j.cell.2008.10.013. Cell. 2008. PMID: 18984153 Free article.

9

Synaptic vesicle distribution by conveyor belt.

Moughamian AJ, Holzbaur EL. Moughamian AJ, et al. Cell. 2012 Mar 2;148(5):849-51. doi: 10.1016/j.cell.2012.02.007. Cell. 2012. PMID: 22385955 Free article.

10

Optineurin is an autophagy receptor for damaged mitochondria in parkin-mediated mitophagy that is disrupted by an ALS-linked mutation.

Wong YC, Holzbaur EL. Wong YC, et al. Proc Natl Acad Sci U S A. 2014 Oct 21;111(42):E4439-48. doi: 10.1073/pnas.1405752111. Epub 2014 Oct 7. Proc Natl Acad Sci U S A. 2014. PMID: 25294927 Free PMC article.

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