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Page 1
Editorial: Hormone resistance in cancer.
Phoenix JT, Budreika A, Kostlan RJ, Hwang JH, Fanning SW, Kregel S. Phoenix JT, et al. Among authors: kregel s. Front Endocrinol (Lausanne). 2023 Aug 24;14:1272932. doi: 10.3389/fendo.2023.1272932. eCollection 2023. Front Endocrinol (Lausanne). 2023. PMID: 37693345 Free PMC article. No abstract available.
SOX2 expression in prostate cancer drives resistance to nuclear hormone receptor signaling inhibition through the WEE1/CDK1 signaling axis.
Williams A, Gutgesell L, de Wet L, Selman P, Dey A, Avineni M, Kapoor I, Mendez M, Brown R, Lamperis S, Blajszczak C, Bueter E, Kregel S, Vander Griend DJ, Szmulewitz RZ. Williams A, et al. Among authors: kregel s. Cancer Lett. 2023 Jul 1;565:216209. doi: 10.1016/j.canlet.2023.216209. Epub 2023 May 9. Cancer Lett. 2023. PMID: 37169162 Free article.
ERBB3 Overexpression is Enriched in Diverse Patient Populations with Castration-sensitive Prostate Cancer and is Associated with a Unique AR Activity Signature.
Vellky JE, Kirkpatrick BJ, Gutgesell LC, Morales M, Brown RM, Wu Y, Maienschein-Cline M, Notardonato LD, Weinfeld MS, Nguyen RH, Brister E, Sverdlov M, Liu L, Xu Z, Kregel S, Nonn L, Vander Griend DJ, Reizine NM. Vellky JE, et al. Among authors: kregel s. Clin Cancer Res. 2024 Apr 15;30(8):1530-1543. doi: 10.1158/1078-0432.CCR-23-2161. Clin Cancer Res. 2024. PMID: 38306015 Free PMC article.
Regulation of Prostate Androgens by Megalin and 25-hydroxyvitamin D Status: Mechanism for High Prostate Androgens in African American Men.
Garcia J, Krieger KD, Loitz C, Perez LM, Richards ZA, Helou Y, Kregel S, Celada S, Mesaros CA, Bosland M, Gann PH, Willnow TE, Vander Griend D, Kittles R, Prins GS, Penning T, Nonn L. Garcia J, et al. Among authors: kregel s. Cancer Res Commun. 2023 Mar 3;3(3):371-382. doi: 10.1158/2767-9764.CRC-22-0362. eCollection 2023 Mar. Cancer Res Commun. 2023. PMID: 36875158 Free PMC article.
Discovery of ARD-1676 as a Highly Potent and Orally Efficacious AR PROTAC Degrader with a Broad Activity against AR Mutants for the Treatment of AR + Human Prostate Cancer.
Xiang W, Zhao L, Han X, Xu T, Kregel S, Wang M, Miao B, Qin C, Wang M, McEachern D, Lu J, Bai L, Yang CY, Kirchhoff PD, Takyi-Williams J, Wang L, Wen B, Sun D, Ator M, Mckean R, Chinnaiyan AM, Wang S. Xiang W, et al. Among authors: kregel s. J Med Chem. 2023 Sep 28;66(18):13280-13303. doi: 10.1021/acs.jmedchem.3c01264. Epub 2023 Sep 8. J Med Chem. 2023. PMID: 37683104
Corrigendum to 'Androgen receptor degraders overcome common resistance mechanisms developed during prostate cancer treatment' Neoplasia, Volume 22, Issue 2 (2020) 111-119.
Kregel S, Wang C, Han X, Xiao L, Fernandez-Salas E, Bawa P, McCollum BL, Wilder-Romans K, Apel IJ, Cao X, Speers C, Wang S, Chinnaiyan AM. Kregel S, et al. Neoplasia. 2024 May;51:100986. doi: 10.1016/j.neo.2024.100986. Epub 2024 Mar 15. Neoplasia. 2024. PMID: 38492449 Free PMC article. No abstract available.
Author Correction: Targeting SWI/SNF ATPases in enhancer-addicted prostate cancer.
Xiao L, Parolia A, Qiao Y, Bawa P, Eyunni S, Mannan R, Carson SE, Chang Y, Wang X, Zhang Y, Vo JN, Kregel S, Simko SA, Delekta AD, Jaber M, Zheng H, Apel IJ, McMurry L, Su F, Wang R, Zelenka-Wang S, Sasmal S, Khare L, Mukherjee S, Abbineni C, Aithal K, Bhakta MS, Ghurye J, Cao X, Navone NM, Nesvizhskii AI, Mehra R, Vaishampayan U, Blanchette M, Wang Y, Samajdar S, Ramachandra M, Chinnaiyan AM. Xiao L, et al. Among authors: kregel s. Nature. 2024 May;629(8011):E9. doi: 10.1038/s41586-024-07393-1. Nature. 2024. PMID: 38649489 Free PMC article. No abstract available.
CREB5 reprograms FOXA1 nuclear interactions to promote resistance to androgen receptor-targeting therapies.
Hwang JH, Arafeh R, Seo JH, Baca SC, Ludwig M, Arnoff TE, Sawyer L, Richter C, Tape S, Bergom HE, McSweeney S, Rennhack JP, Klingenberg SA, Cheung ATM, Kwon J, So J, Kregel S, Van Allen EM, Drake JM, Freedman ML, Hahn WC. Hwang JH, et al. Among authors: kregel s. Elife. 2022 May 12;11:e73223. doi: 10.7554/eLife.73223. Elife. 2022. PMID: 35550030 Free PMC article.
38 results