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Page 1
A systems vaccinology resource to develop and test computational models of immunity.
Shinde P, Soldevila F, Reyna J, Aoki M, Rasmussen M, Willemsen L, Kojima M, Ha B, Greenbaum JA, Overton JA, Guzman-Orozco H, Nili S, Orfield S, Gygi JP, da Silva Antunes R, Sette A, Grant B, Olsen LR, Konstorum A, Guan L, Ay F, Kleinstein SH, Peters B. Shinde P, et al. Among authors: kleinstein sh. bioRxiv [Preprint]. 2023 Aug 29:2023.08.28.555193. doi: 10.1101/2023.08.28.555193. bioRxiv. 2023. PMID: 37693565 Free PMC article. Updated. Preprint.
A structured model for immune exposures.
Vita R, Overton JA, Dunn P, Cheung KH, Kleinstein SH, Sette A, Peters B. Vita R, et al. Among authors: kleinstein sh. Database (Oxford). 2020 Jan 1;2020:baaa016. doi: 10.1093/database/baaa016. Database (Oxford). 2020. PMID: 32283555 Free PMC article.
Phenotypes of disease severity in a cohort of hospitalized COVID-19 patients: Results from the IMPACC study.
Ozonoff A, Schaenman J, Jayavelu ND, Milliren CE, Calfee CS, Cairns CB, Kraft M, Baden LR, Shaw AC, Krammer F, van Bakel H, Esserman DA, Liu S, Sesma AF, Simon V, Hafler DA, Montgomery RR, Kleinstein SH, Levy O, Bime C, Haddad EK, Erle DJ, Pulendran B, Nadeau KC, Davis MM, Hough CL, Messer WB, Higuita NIA, Metcalf JP, Atkinson MA, Brakenridge SC, Corry D, Kheradmand F, Ehrlich LIR, Melamed E, McComsey GA, Sekaly R, Diray-Arce J, Peters B, Augustine AD, Reed EF, Altman MC, Becker PM, Rouphael N; IMPACC study group members. Ozonoff A, et al. Among authors: kleinstein sh. EBioMedicine. 2022 Sep;83:104208. doi: 10.1016/j.ebiom.2022.104208. Epub 2022 Aug 8. EBioMedicine. 2022. PMID: 35952496 Free PMC article.
The Immune Signatures data resource, a compendium of systems vaccinology datasets.
Diray-Arce J, Miller HER, Henrich E, Gerritsen B, Mulè MP, Fourati S, Gygi J, Hagan T, Tomalin L, Rychkov D, Kazmin D, Chawla DG, Meng H, Dunn P, Campbell J; Human Immunology Project Consortium (HIPC); Sarwal M, Tsang JS, Levy O, Pulendran B, Sekaly R, Floratos A, Gottardo R, Kleinstein SH, Suárez-Fariñas M. Diray-Arce J, et al. Among authors: kleinstein sh. Sci Data. 2022 Oct 20;9(1):635. doi: 10.1038/s41597-022-01714-7. Sci Data. 2022. PMID: 36266291 Free PMC article.
Pan-vaccine analysis reveals innate immune endotypes predictive of antibody responses to vaccination.
Fourati S, Tomalin LE, Mulè MP, Chawla DG, Gerritsen B, Rychkov D, Henrich E, Miller HER, Hagan T, Diray-Arce J, Dunn P; Human Immunology Project Consortium (HIPC); Levy O, Gottardo R, Sarwal MM, Tsang JS, Suárez-Fariñas M, Pulendran B, Kleinstein SH, Sékaly RP. Fourati S, et al. Among authors: kleinstein sh. Nat Immunol. 2022 Dec;23(12):1777-1787. doi: 10.1038/s41590-022-01329-5. Epub 2022 Oct 31. Nat Immunol. 2022. PMID: 36316476 Free PMC article.
A curated collection of human vaccination response signatures.
Smith KC, Chawla DG, Dhillon BK, Ji Z, Vita R, van der Leest EC, Weng JYJ, Tang E, Abid A; Human Immunology Project Consortium (HIPC); Peters B, Hancock REW, Floratos A, Kleinstein SH. Smith KC, et al. Among authors: kleinstein sh. Sci Data. 2022 Nov 8;9(1):678. doi: 10.1038/s41597-022-01558-1. Sci Data. 2022. PMID: 36347894 Free PMC article.
Platelet response to influenza vaccination reflects effects of aging.
Konstorum A, Mohanty S, Zhao Y, Melillo A, Vander Wyk B, Nelson A, Tsang S, Blevins TP, Belshe RB, Chawla DG, Rondina MT, Gill TM, Montgomery RR, Allore HG, Kleinstein SH, Shaw AC. Konstorum A, et al. Among authors: kleinstein sh. Aging Cell. 2023 Feb;22(2):e13749. doi: 10.1111/acel.13749. Epub 2023 Jan 19. Aging Cell. 2023. PMID: 36656789 Free PMC article.
Multi-omic longitudinal study reveals immune correlates of clinical course among hospitalized COVID-19 patients.
Diray-Arce J, Fourati S, Doni Jayavelu N, Patel R, Maguire C, Chang AC, Dandekar R, Qi J, Lee BH, van Zalm P, Schroeder A, Chen E, Konstorum A, Brito A, Gygi JP, Kho A, Chen J, Pawar S, Gonzalez-Reiche AS, Hoch A, Milliren CE, Overton JA, Westendorf K; IMPACC Network; Cairns CB, Rouphael N, Bosinger SE, Kim-Schulze S, Krammer F, Rosen L, Grubaugh ND, van Bakel H, Wilson M, Rajan J, Steen H, Eckalbar W, Cotsapas C, Langelier CR, Levy O, Altman MC, Maecker H, Montgomery RR, Haddad EK, Sekaly RP, Esserman D, Ozonoff A, Becker PM, Augustine AD, Guan L, Peters B, Kleinstein SH. Diray-Arce J, et al. Among authors: kleinstein sh. Cell Rep Med. 2023 Jun 20;4(6):101079. doi: 10.1016/j.xcrm.2023.101079. Epub 2023 May 23. Cell Rep Med. 2023. PMID: 37327781 Free PMC article.
184 results