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Depletion of SAM leading to loss of heterochromatin drives muscle stem cell ageing.
Nat Metab. 2024 Jan;6(1):153-168. doi: 10.1038/s42255-023-00955-z. Epub 2024 Jan 19.
Nat Metab. 2024.
PMID: 38243132
Death-seq identifies regulators of cell death and senolytic therapies.
Colville A, Liu JY, Rodriguez-Mateo C, Thomas S, Ishak HD, Zhou R, Klein JDD, Morgens DW, Goshayeshi A, Salvi JS, Yao D, Spees K, Dixon SJ, Liu C, Rhee JW, Lai C, Wu JC, Bassik MC, Rando TA.
Colville A, et al. Among authors: salvi js.
Cell Metab. 2023 Oct 3;35(10):1814-1829.e6. doi: 10.1016/j.cmet.2023.08.008. Epub 2023 Sep 11.
Cell Metab. 2023.
PMID: 37699398
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ATR activity controls stem cell quiescence via the cyclin F-SCF complex.
Salvi JS, Kang J, Kim S, Colville AJ, de Morrée A, Billeskov TB, Larsen MC, Kanugovi A, van Velthoven CTJ, Cimprich KA, Rando TA.
Salvi JS, et al.
Proc Natl Acad Sci U S A. 2022 May 3;119(18):e2115638119. doi: 10.1073/pnas.2115638119. Epub 2022 Apr 27.
Proc Natl Acad Sci U S A. 2022.
PMID: 35476521
Free PMC article.
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Staufen1 inhibits MyoD translation to actively maintain muscle stem cell quiescence.
de Morrée A, van Velthoven CTJ, Gan Q, Salvi JS, Klein JDD, Akimenko I, Quarta M, Biressi S, Rando TA.
de Morrée A, et al. Among authors: salvi js.
Proc Natl Acad Sci U S A. 2017 Oct 24;114(43):E8996-E9005. doi: 10.1073/pnas.1708725114. Epub 2017 Oct 9.
Proc Natl Acad Sci U S A. 2017.
PMID: 29073096
Free PMC article.
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Intersection of calorie restriction and magnesium in the suppression of genome-destabilizing RNA-DNA hybrids.
Abraham KJ, Chan JN, Salvi JS, Ho B, Hall A, Vidya E, Guo R, Killackey SA, Liu N, Lee JE, Brown GW, Mekhail K.
Abraham KJ, et al. Among authors: salvi js.
Nucleic Acids Res. 2016 Oct 14;44(18):8870-8884. doi: 10.1093/nar/gkw752. Epub 2016 Aug 29.
Nucleic Acids Res. 2016.
PMID: 27574117
Free PMC article.
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R-loops highlight the nucleus in ALS.
Salvi JS, Mekhail K.
Salvi JS, et al.
Nucleus. 2015;6(1):23-9. doi: 10.1080/19491034.2015.1004952.
Nucleus. 2015.
PMID: 25587791
Free PMC article.
Review.
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Roles for Pbp1 and caloric restriction in genome and lifespan maintenance via suppression of RNA-DNA hybrids.
Salvi JS, Chan JN, Szafranski K, Liu TT, Wu JD, Olsen JB, Khanam N, Poon BP, Emili A, Mekhail K.
Salvi JS, et al.
Dev Cell. 2014 Jul 28;30(2):177-91. doi: 10.1016/j.devcel.2014.05.013.
Dev Cell. 2014.
PMID: 25073155
Free article.
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Enforcement of a lifespan-sustaining distribution of Sir2 between telomeres, mating-type loci, and rDNA repeats by Rif1.
Salvi JS, Chan JN, Pettigrew C, Liu TT, Wu JD, Mekhail K.
Salvi JS, et al.
Aging Cell. 2013 Feb;12(1):67-75. doi: 10.1111/acel.12020. Epub 2012 Nov 23.
Aging Cell. 2013.
PMID: 23082874
Free article.
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