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720 results

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Page 1
Therapeutic blockade of ER stress and inflammation prevents NASH and progression to HCC.
Boslem E, Reibe S, Carlessi R, Smeuninx B, Tegegne S, Egan CL, McLennan E, Terry LV, Nobis M, Mu A, Nowell C, Horadagoda N, Henstridge DC, Mellett NA, Timpson P, Jones M, Denisenko E, Forrest ARR, Tirnitz-Parker JEE, Meikle PJ, Rose-John S, Karin M, Febbraio MA. Boslem E, et al. Among authors: karin m. Sci Adv. 2023 Sep 15;9(37):eadh0831. doi: 10.1126/sciadv.adh0831. Epub 2023 Sep 13. Sci Adv. 2023. PMID: 37703359 Free PMC article.
Single-nucleus RNA sequencing of pre-malignant liver reveals disease-associated hepatocyte state with HCC prognostic potential.
Carlessi R, Denisenko E, Boslem E, Köhn-Gaone J, Main N, Abu Bakar NDB, Shirolkar GD, Jones M, Beasley AB, Poppe D, Dwyer BJ, Jackaman C, Tjiam MC, Lister R, Karin M, Fallowfield JA, Kendall TJ, Forbes SJ, Gray ES, Olynyk JK, Yeoh G, Forrest ARR, Ramm GA, Febbraio MA, Tirnitz-Parker JEE. Carlessi R, et al. Among authors: karin m. Cell Genom. 2023 Apr 13;3(5):100301. doi: 10.1016/j.xgen.2023.100301. eCollection 2023 May 10. Cell Genom. 2023. PMID: 37228755 Free PMC article.
Effects of Early Life Oral Arsenic Exposure on Intestinal Tract Development and Lipid Homeostasis in Neonatal Mice: Implications for NAFLD Development.
Yang X, Weber AA, Mennillo E, Secrest P, Chang M, Wong S, Le S, Liu J, Benner CW, Karin M, Gordts PLSM, Tukey RH, Chen S. Yang X, et al. Among authors: karin m. Environ Health Perspect. 2023 Sep;131(9):97001. doi: 10.1289/EHP12381. Epub 2023 Sep 5. Environ Health Perspect. 2023. PMID: 37668303 Free PMC article.
Hepatic stellate cell stearoyl co-A desaturase activates leukotriene B4 receptor 2 - β-catenin cascade to promote liver tumorigenesis.
Sinha S, Aizawa S, Nakano Y, Rialdi A, Choi HY, Shrestha R, Pan SQ, Chen Y, Li M, Kapelanski-Lamoureux A, Yochum G, Sher L, Monga SP, Lazaris A, Machida K, Karin M, Guccione E, Tsukamoto H. Sinha S, et al. Among authors: karin m. Nat Commun. 2023 May 8;14(1):2651. doi: 10.1038/s41467-023-38406-8. Nat Commun. 2023. PMID: 37156770 Free PMC article.
Apoptotic cell death in disease-Current understanding of the NCCD 2023.
Vitale I, Pietrocola F, Guilbaud E, Aaronson SA, Abrams JM, Adam D, Agostini M, Agostinis P, Alnemri ES, Altucci L, Amelio I, Andrews DW, Aqeilan RI, Arama E, Baehrecke EH, Balachandran S, Bano D, Barlev NA, Bartek J, Bazan NG, Becker C, Bernassola F, Bertrand MJM, Bianchi ME, Blagosklonny MV, Blander JM, Blandino G, Blomgren K, Borner C, Bortner CD, Bove P, Boya P, Brenner C, Broz P, Brunner T, Damgaard RB, Calin GA, Campanella M, Candi E, Carbone M, Carmona-Gutierrez D, Cecconi F, Chan FK, Chen GQ, Chen Q, Chen YH, Cheng EH, Chipuk JE, Cidlowski JA, Ciechanover A, Ciliberto G, Conrad M, Cubillos-Ruiz JR, Czabotar PE, D'Angiolella V, Daugaard M, Dawson TM, Dawson VL, De Maria R, De Strooper B, Debatin KM, Deberardinis RJ, Degterev A, Del Sal G, Deshmukh M, Di Virgilio F, Diederich M, Dixon SJ, Dynlacht BD, El-Deiry WS, Elrod JW, Engeland K, Fimia GM, Galassi C, Ganini C, Garcia-Saez AJ, Garg AD, Garrido C, Gavathiotis E, Gerlic M, Ghosh S, Green DR, Greene LA, Gronemeyer H, Häcker G, Hajnóczky G, Hardwick JM, Haupt Y, He S, Heery DM, Hengartner MO, Hetz C, Hildeman DA, Ichijo H, Inoue S, Jäättelä M, Janic A, Joseph B, Jost PJ, Kanneganti TD, Karin M, Kashkar H, Kaufmann T,… See abstract for full author list ➔ Vitale I, et al. Among authors: karin m. Cell Death Differ. 2023 May;30(5):1097-1154. doi: 10.1038/s41418-023-01153-w. Epub 2023 Apr 26. Cell Death Differ. 2023. PMID: 37100955 Free PMC article. Review.
A guideline on the molecular ecosystem regulating ferroptosis.
Dai E, Chen X, Linkermann A, Jiang X, Kang R, Kagan VE, Bayir H, Yang WS, Garcia-Saez AJ, Ioannou MS, Janowitz T, Ran Q, Gu W, Gan B, Krysko DV, Zhu X, Wang J, Krautwald S, Toyokuni S, Xie Y, Greten FR, Yi Q, Schick J, Liu J, Gabrilovich DI, Liu J, Zeh HJ, Zhang DD, Yang M, Iovanna J, Kopf M, Adolph TE, Chi JT, Li C, Ichijo H, Karin M, Sankaran VG, Zou W, Galluzzi L, Bush AI, Li B, Melino G, Baehrecke EH, Lotze MT, Klionsky DJ, Stockwell BR, Kroemer G, Tang D. Dai E, et al. Among authors: karin m. Nat Cell Biol. 2024 Feb 29. doi: 10.1038/s41556-024-01360-8. Online ahead of print. Nat Cell Biol. 2024. PMID: 38424270 Review.
Genuine selective caspase-2 inhibition with new irreversible small peptidomimetics.
Bosc E, Anastasie J, Soualmia F, Coric P, Kim JY, Wang LQ, Lacin G, Zhao K, Patel R, Duplus E, Tixador P, Sproul AA, Brugg B, Reboud-Ravaux M, Troy CM, Shelanski ML, Bouaziz S, Karin M, El Amri C, Jacotot ED. Bosc E, et al. Among authors: karin m. Cell Death Dis. 2022 Nov 15;13(11):959. doi: 10.1038/s41419-022-05396-2. Cell Death Dis. 2022. PMID: 36379916 Free PMC article.
720 results