Meikle PJ - Search Results

1

Therapeutic blockade of ER stress and inflammation prevents NASH and progression to HCC.

Boslem E, Reibe S, Carlessi R, Smeuninx B, Tegegne S, Egan CL, McLennan E, Terry LV, Nobis M, Mu A, Nowell C, Horadagoda N, Henstridge DC, Mellett NA, Timpson P, Jones M, Denisenko E, Forrest ARR, Tirnitz-Parker JEE, Meikle PJ, Rose-John S, Karin M, Febbraio MA. Boslem E, et al. Among authors: meikle pj. Sci Adv. 2023 Sep 15;9(37):eadh0831. doi: 10.1126/sciadv.adh0831. Epub 2023 Sep 13. Sci Adv. 2023. PMID: 37703359 Free PMC article.

2

Interleukin-6-deficient mice develop hepatic inflammation and systemic insulin resistance.

Matthews VB, Allen TL, Risis S, Chan MH, Henstridge DC, Watson N, Zaffino LA, Babb JR, Boon J, Meikle PJ, Jowett JB, Watt MJ, Jansson JO, Bruce CR, Febbraio MA. Matthews VB, et al. Among authors: meikle pj. Diabetologia. 2010 Nov;53(11):2431-41. doi: 10.1007/s00125-010-1865-y. Epub 2010 Aug 11. Diabetologia. 2010. PMID: 20697689

3

A lipidomic screen of palmitate-treated MIN6 β-cells links sphingolipid metabolites with endoplasmic reticulum (ER) stress and impaired protein trafficking.

Boslem E, MacIntosh G, Preston AM, Bartley C, Busch AK, Fuller M, Laybutt DR, Meikle PJ, Biden TJ. Boslem E, et al. Among authors: meikle pj. Biochem J. 2011 Apr 1;435(1):267-76. doi: 10.1042/BJ20101867. Biochem J. 2011. PMID: 21265737

4

Roles of ceramide and sphingolipids in pancreatic β-cell function and dysfunction.

Boslem E, Meikle PJ, Biden TJ. Boslem E, et al. Among authors: meikle pj. Islets. 2012 May-Jun;4(3):177-87. doi: 10.4161/isl.20102. Islets. 2012. PMID: 22847494 Free PMC article. Review.

5

Plasma lysophosphatidylcholine levels are reduced in obesity and type 2 diabetes.

Barber MN, Risis S, Yang C, Meikle PJ, Staples M, Febbraio MA, Bruce CR. Barber MN, et al. Among authors: meikle pj. PLoS One. 2012;7(7):e41456. doi: 10.1371/journal.pone.0041456. Epub 2012 Jul 25. PLoS One. 2012. PMID: 22848500 Free PMC article. Clinical Trial.

6

Overexpression of sphingosine kinase 1 prevents ceramide accumulation and ameliorates muscle insulin resistance in high-fat diet-fed mice.

Bruce CR, Risis S, Babb JR, Yang C, Kowalski GM, Selathurai A, Lee-Young RS, Weir JM, Yoshioka K, Takuwa Y, Meikle PJ, Pitson SM, Febbraio MA. Bruce CR, et al. Among authors: meikle pj. Diabetes. 2012 Dec;61(12):3148-55. doi: 10.2337/db12-0029. Epub 2012 Sep 6. Diabetes. 2012. PMID: 22961081 Free PMC article.

7

Distinct patterns of tissue-specific lipid accumulation during the induction of insulin resistance in mice by high-fat feeding.

Turner N, Kowalski GM, Leslie SJ, Risis S, Yang C, Lee-Young RS, Babb JR, Meikle PJ, Lancaster GI, Henstridge DC, White PJ, Kraegen EW, Marette A, Cooney GJ, Febbraio MA, Bruce CR. Turner N, et al. Among authors: meikle pj. Diabetologia. 2013 Jul;56(7):1638-48. doi: 10.1007/s00125-013-2913-1. Epub 2013 Apr 26. Diabetologia. 2013. PMID: 23620060

8

Effects of low-fat or full-fat fermented and non-fermented dairy foods on selected cardiovascular biomarkers in overweight adults.

Nestel PJ, Mellett N, Pally S, Wong G, Barlow CK, Croft K, Mori TA, Meikle PJ. Nestel PJ, et al. Among authors: meikle pj. Br J Nutr. 2013 Dec;110(12):2242-9. doi: 10.1017/S0007114513001621. Epub 2013 Jun 12. Br J Nutr. 2013. PMID: 23756569 Free article. Clinical Trial.

9

Alteration of endoplasmic reticulum lipid rafts contributes to lipotoxicity in pancreatic β-cells.

Boslem E, Weir JM, MacIntosh G, Sue N, Cantley J, Meikle PJ, Biden TJ. Boslem E, et al. Among authors: meikle pj. J Biol Chem. 2013 Sep 13;288(37):26569-82. doi: 10.1074/jbc.M113.489310. Epub 2013 Jul 29. J Biol Chem. 2013. PMID: 23897822 Free PMC article.

10

Lysosomal acid lipase and lipophagy are constitutive negative regulators of glucose-stimulated insulin secretion from pancreatic beta cells.

Pearson GL, Mellett N, Chu KY, Cantley J, Davenport A, Bourbon P, Cosner CC, Helquist P, Meikle PJ, Biden TJ. Pearson GL, et al. Among authors: meikle pj. Diabetologia. 2014 Jan;57(1):129-39. doi: 10.1007/s00125-013-3083-x. Epub 2013 Oct 23. Diabetologia. 2014. PMID: 24149836

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