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MEG3 activates necroptosis in human neuron xenografts modeling Alzheimer's disease.
Balusu S, Horré K, Thrupp N, Craessaerts K, Snellinx A, Serneels L, T'Syen D, Chrysidou I, Arranz AM, Sierksma A, Simrén J, Karikari TK, Zetterberg H, Chen WT, Thal DR, Salta E, Fiers M, De Strooper B. Balusu S, et al. Among authors: horre k. Science. 2023 Sep 15;381(6663):1176-1182. doi: 10.1126/science.abp9556. Epub 2023 Sep 14. Science. 2023. PMID: 37708272 Free PMC article.
gamma-Secretase heterogeneity in the Aph1 subunit: relevance for Alzheimer's disease.
Serneels L, Van Biervliet J, Craessaerts K, Dejaegere T, Horré K, Van Houtvin T, Esselmann H, Paul S, Schäfer MK, Berezovska O, Hyman BT, Sprangers B, Sciot R, Moons L, Jucker M, Yang Z, May PC, Karran E, Wiltfang J, D'Hooge R, De Strooper B. Serneels L, et al. Among authors: horre k. Science. 2009 May 1;324(5927):639-42. doi: 10.1126/science.1171176. Epub 2009 Mar 19. Science. 2009. PMID: 19299585 Free PMC article.
Restoring miR-132 expression rescues adult hippocampal neurogenesis and memory deficits in Alzheimer's disease.
Walgrave H, Balusu S, Snoeck S, Vanden Eynden E, Craessaerts K, Thrupp N, Wolfs L, Horré K, Fourne Y, Ronisz A, Silajdžić E, Penning A, Tosoni G, Callaerts-Vegh Z, D'Hooge R, Thal DR, Zetterberg H, Thuret S, Fiers M, Frigerio CS, De Strooper B, Salta E. Walgrave H, et al. Among authors: horre k. Cell Stem Cell. 2021 Oct 7;28(10):1805-1821.e8. doi: 10.1016/j.stem.2021.05.001. Epub 2021 May 24. Cell Stem Cell. 2021. PMID: 34033742 Free article.
Astrocyte calcium dysfunction causes early network hyperactivity in Alzheimer's disease.
Shah D, Gsell W, Wahis J, Luckett ES, Jamoulle T, Vermaercke B, Preman P, Moechars D, Hendrickx V, Jaspers T, Craessaerts K, Horré K, Wolfs L, Fiers M, Holt M, Thal DR, Callaerts-Vegh Z, D'Hooge R, Vandenberghe R, Himmelreich U, Bonin V, De Strooper B. Shah D, et al. Among authors: horre k. Cell Rep. 2022 Aug 23;40(8):111280. doi: 10.1016/j.celrep.2022.111280. Cell Rep. 2022. PMID: 36001964 Free PMC article.
Loss of GPR3 reduces the amyloid plaque burden and improves memory in Alzheimer's disease mouse models.
Huang Y, Skwarek-Maruszewska A, Horré K, Vandewyer E, Wolfs L, Snellinx A, Saito T, Radaelli E, Corthout N, Colombelli J, Lo AC, Van Aerschot L, Callaerts-Vegh Z, Trabzuni D, Bossers K, Verhaagen J, Ryten M, Munck S, D'Hooge R, Swaab DF, Hardy J, Saido TC, De Strooper B, Thathiah A. Huang Y, et al. Among authors: horre k. Sci Transl Med. 2015 Oct 14;7(309):309ra164. doi: 10.1126/scitranslmed.aab3492. Sci Transl Med. 2015. PMID: 26468326
Tetraspanin 6: a pivotal protein of the multiple vesicular body determining exosome release and lysosomal degradation of amyloid precursor protein fragments.
Guix FX, Sannerud R, Berditchevski F, Arranz AM, Horré K, Snellinx A, Thathiah A, Saido T, Saito T, Rajesh S, Overduin M, Kumar-Singh S, Radaelli E, Corthout N, Colombelli J, Tosi S, Munck S, Salas IH, Annaert W, De Strooper B. Guix FX, et al. Among authors: horre k. Mol Neurodegener. 2017 Mar 10;12(1):25. doi: 10.1186/s13024-017-0165-0. Mol Neurodegener. 2017. PMID: 28279219 Free PMC article.
PLD3 gene and processing of APP.
Fazzari P, Horre K, Arranz AM, Frigerio CS, Saito T, Saido TC, De Strooper B. Fazzari P, et al. Among authors: horre k. Nature. 2017 Jan 25;541(7638):E1-E2. doi: 10.1038/nature21030. Nature. 2017. PMID: 28128235 No abstract available.
PARL deficiency in mouse causes Complex III defects, coenzyme Q depletion, and Leigh-like syndrome.
Spinazzi M, Radaelli E, Horré K, Arranz AM, Gounko NV, Agostinis P, Maia TM, Impens F, Morais VA, Lopez-Lluch G, Serneels L, Navas P, De Strooper B. Spinazzi M, et al. Among authors: horre k. Proc Natl Acad Sci U S A. 2019 Jan 2;116(1):277-286. doi: 10.1073/pnas.1811938116. Epub 2018 Dec 21. Proc Natl Acad Sci U S A. 2019. PMID: 30578322 Free PMC article.
25 results