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MEG3 activates necroptosis in human neuron xenografts modeling Alzheimer's disease.
Balusu S, Horré K, Thrupp N, Craessaerts K, Snellinx A, Serneels L, T'Syen D, Chrysidou I, Arranz AM, Sierksma A, Simrén J, Karikari TK, Zetterberg H, Chen WT, Thal DR, Salta E, Fiers M, De Strooper B. Balusu S, et al. Among authors: salta e. Science. 2023 Sep 15;381(6663):1176-1182. doi: 10.1126/science.abp9556. Epub 2023 Sep 14. Science. 2023. PMID: 37708272 Free PMC article.
microRNA-132: a key noncoding RNA operating in the cellular phase of Alzheimer's disease.
Salta E, De Strooper B. Salta E, et al. FASEB J. 2017 Feb;31(2):424-433. doi: 10.1096/fj.201601308. FASEB J. 2017. PMID: 28148775 Review.
We describe the potential therapeutic implications of these findings and suggest miRNA targeting or replacement as a realistic multi-hit, therapeutic strategy for AD. Salta, E., De Strooper, B. microRNA-132: a key noncoding RNA operating in the cellular phase of Alz …
We describe the potential therapeutic implications of these findings and suggest miRNA targeting or replacement as a realistic multi-hit, th …
Spatial Transcriptomics and In Situ Sequencing to Study Alzheimer's Disease.
Chen WT, Lu A, Craessaerts K, Pavie B, Sala Frigerio C, Corthout N, Qian X, Laláková J, Kühnemund M, Voytyuk I, Wolfs L, Mancuso R, Salta E, Balusu S, Snellinx A, Munck S, Jurek A, Fernandez Navarro J, Saido TC, Huitinga I, Lundeberg J, Fiers M, De Strooper B. Chen WT, et al. Among authors: salta e. Cell. 2020 Aug 20;182(4):976-991.e19. doi: 10.1016/j.cell.2020.06.038. Epub 2020 Jul 22. Cell. 2020. PMID: 32702314 Free article.
Restoring miR-132 expression rescues adult hippocampal neurogenesis and memory deficits in Alzheimer's disease.
Walgrave H, Balusu S, Snoeck S, Vanden Eynden E, Craessaerts K, Thrupp N, Wolfs L, Horré K, Fourne Y, Ronisz A, Silajdžić E, Penning A, Tosoni G, Callaerts-Vegh Z, D'Hooge R, Thal DR, Zetterberg H, Thuret S, Fiers M, Frigerio CS, De Strooper B, Salta E. Walgrave H, et al. Among authors: salta e. Cell Stem Cell. 2021 Oct 7;28(10):1805-1821.e8. doi: 10.1016/j.stem.2021.05.001. Epub 2021 May 24. Cell Stem Cell. 2021. PMID: 34033742 Free article.
Noncoding RNAs in neurodegeneration.
Salta E, De Strooper B. Salta E, et al. Nat Rev Neurosci. 2017 Oct;18(10):627-640. doi: 10.1038/nrn.2017.90. Epub 2017 Aug 17. Nat Rev Neurosci. 2017. PMID: 28855739 Free article. Review.
Deregulation of neuronal miRNAs induced by amyloid-β or TAU pathology.
Sierksma A, Lu A, Salta E, Vanden Eynden E, Callaerts-Vegh Z, D'Hooge R, Blum D, Buée L, Fiers M, De Strooper B. Sierksma A, et al. Among authors: salta e. Mol Neurodegener. 2018 Oct 12;13(1):54. doi: 10.1186/s13024-018-0285-1. Mol Neurodegener. 2018. PMID: 30314521 Free PMC article.
29 results