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Activation of the transcription factor NFAT5 in the tumor microenvironment enforces CD8+ T cell exhaustion.
Tillé L, Cropp D, Charmoy M, Reichenbach P, Andreatta M, Wyss T, Bodley G, Crespo I, Nassiri S, Lourenco J, Leblond MM, Lopez-Rodriguez C, Speiser DE, Coukos G, Irving M, Carmona SJ, Held W, Verdeil G. Tillé L, et al. Among authors: lopez rodriguez c. Nat Immunol. 2023 Oct;24(10):1645-1653. doi: 10.1038/s41590-023-01614-x. Epub 2023 Sep 14. Nat Immunol. 2023. PMID: 37709986
NFAT5 Controls the Integrity of Epidermis.
Muhammad K, Xavier D, Klein-Hessling S, Azeem M, Rauschenberger T, Murti K, Avots A, Goebeler M, Klein M, Bopp T, Sielaff M, Tenzer S, Möckel S, Aramburu J, López-Rodríguez C, Kerstan A, Serfling E. Muhammad K, et al. Among authors: lopez rodriguez c. Front Immunol. 2021 Dec 9;12:780727. doi: 10.3389/fimmu.2021.780727. eCollection 2021. Front Immunol. 2021. PMID: 34956208 Free PMC article.
NFAT5 Amplifies Antipathogen Responses by Enhancing Chromatin Accessibility, H3K27 Demethylation, and Transcription Factor Recruitment.
Lunazzi G, Buxadé M, Riera-Borrull M, Higuera L, Bonnin S, Huerga Encabo H, Gaggero S, Reyes-Garau D, Company C, Cozzuto L, Ponomarenko J, Aramburu J, López-Rodríguez C. Lunazzi G, et al. Among authors: lopez rodriguez c. J Immunol. 2021 Jun 1;206(11):2652-2667. doi: 10.4049/jimmunol.2000624. Epub 2021 May 24. J Immunol. 2021. PMID: 34031145 Free PMC article.
Immunodeficiency and autoimmune enterocolopathy linked to NFAT5 haploinsufficiency.
Boland BS, Widjaja CE, Banno A, Zhang B, Kim SH, Stoven S, Peterson MR, Jones MC, Su HI, Crowe SE, Bui JD, Ho SB, Okugawa Y, Goel A, Marietta EV, Khosroheidari M, Jepsen K, Aramburu J, López-Rodríguez C, Sandborn WJ, Murray JA, Harismendy O, Chang JT. Boland BS, et al. J Immunol. 2015 Mar 15;194(6):2551-60. doi: 10.4049/jimmunol.1401463. Epub 2015 Feb 9. J Immunol. 2015. PMID: 25667416 Free PMC article.
80 results