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Page 1
Selective Bias Virtual Screening for Discovery of Promising Antimalarial Candidates targeting Plasmodium N-Myristoyltransferase.
Andrade C, Sousa BKP, Sigurdardóttir S, Bourgard C, Borba J, Clementino L, Salazar-Alvarez LC, Groustra S, Zigweid R, Khim M, Staker B, Costa F, Eriksson L, Sunnerhagen P. Andrade C, et al. Among authors: zigweid r. Res Sq [Preprint]. 2024 Feb 20:rs.3.rs-3963523. doi: 10.21203/rs.3.rs-3963523/v1. Res Sq. 2024. PMID: 38463971 Free PMC article. Preprint.
Identification of and Structural Insights into Hit Compounds Targeting N-Myristoyltransferase for Cryptosporidium Drug Development.
Fenwick MK, Reers AR, Liu Y, Zigweid R, Sankaran B, Shin J, Hulverson MA, Hammerson B, Fernández Álvaro E, Myler PJ, Kaushansky A, Van Voorhis WC, Fan E, Staker BL. Fenwick MK, et al. Among authors: zigweid r. ACS Infect Dis. 2023 Oct 13;9(10):1821-1833. doi: 10.1021/acsinfecdis.3c00151. Epub 2023 Sep 18. ACS Infect Dis. 2023. PMID: 37722671 Free PMC article.
Identification of potent and selective N-myristoyltransferase inhibitors of Plasmodium vivax liver stage hypnozoites and schizonts.
Rodríguez-Hernández D, Vijayan K, Zigweid R, Fenwick MK, Sankaran B, Roobsoong W, Sattabongkot J, Glennon EKK, Myler PJ, Sunnerhagen P, Staker BL, Kaushansky A, Grøtli M. Rodríguez-Hernández D, et al. Among authors: zigweid r. Nat Commun. 2023 Sep 5;14(1):5408. doi: 10.1038/s41467-023-41119-7. Nat Commun. 2023. PMID: 37669940 Free PMC article.
Structure-Guided Discovery of N5-CAIR Mutase Inhibitors.
Belfon KKJ, Sharma N, Zigweid R, Bolejack M, Davies D, Edwards TE, Myler PJ, French JB. Belfon KKJ, et al. Among authors: zigweid r. Biochemistry. 2023 Sep 5;62(17):2587-2596. doi: 10.1021/acs.biochem.2c00705. Epub 2023 Aug 8. Biochemistry. 2023. PMID: 37552766 Free article.
Characterization of Glucokinases from Pathogenic Free-Living Amoebae.
Milanes JE, Suryadi J, Monaghan NP, Harding EM, Morris CS, Rozema SD, Khalifa MM, Golden JE, Phan IQ, Zigweid R, Abendroth J, Rice CA, McCord HT, Wilson S, Fenwick MK, Morris JC. Milanes JE, et al. Among authors: zigweid r. Antimicrob Agents Chemother. 2022 Jun 21;66(6):e0237321. doi: 10.1128/aac.02373-21. Epub 2022 May 23. Antimicrob Agents Chemother. 2022. PMID: 35604214 Free PMC article.