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CD4+ T Cell Responses to Toxoplasma gondii Are a Double-Edged Sword.
El Bissati K, Krishack PA, Zhou Y, Weber CR, Lykins J, Jankovic D, Edelblum KL, Fraczek L, Grover H, Chentoufi AA, Singh G, Reardon C, Dubey JP, Reed S, Alexander J, Sidney J, Sette A, Shastri N, McLeod R. El Bissati K, et al. Among authors: alexander j. Vaccines (Basel). 2023 Sep 14;11(9):1485. doi: 10.3390/vaccines11091485. Vaccines (Basel). 2023. PMID: 37766162 Free PMC article.
Protein nanovaccine confers robust immunity against Toxoplasma.
El Bissati K, Zhou Y, Paulillo SM, Raman SK, Karch CP, Roberts CW, Lanar DE, Reed S, Fox C, Carter D, Alexander J, Sette A, Sidney J, Lorenzi H, Begeman IJ, Burkhard P, McLeod R. El Bissati K, et al. Among authors: alexander j. NPJ Vaccines. 2017 Sep 5;2:24. doi: 10.1038/s41541-017-0024-6. eCollection 2017. NPJ Vaccines. 2017. PMID: 29263879 Free PMC article.
Adjuvanted multi-epitope vaccines protect HLA-A*11:01 transgenic mice against Toxoplasma gondii.
El Bissati K, Chentoufi AA, Krishack PA, Zhou Y, Woods S, Dubey JP, Vang L, Lykins J, Broderick KE, Mui E, Suzuki Y, Sa Q, Bi S, Cardona N, Verma SK, Fraczek L, Reardon CA, Sidney J, Alexander J, Sette A, Vedvick T, Fox C, Guderian JA, Reed S, Roberts CW, McLeod R. El Bissati K, et al. Among authors: alexander j. JCI Insight. 2016 Sep 22;1(15):e85955. doi: 10.1172/jci.insight.85955. JCI Insight. 2016. PMID: 27699241 Free PMC article.
Human immunome, bioinformatic analyses using HLA supermotifs and the parasite genome, binding assays, studies of human T cell responses, and immunization of HLA-A*1101 transgenic mice including novel adjuvants provide a foundation for HLA-A03 restricted CD8+T cell epitope based, adjuvanted vaccine protective against Toxoplasma gondii.
Cong H, Mui EJ, Witola WH, Sidney J, Alexander J, Sette A, Maewal A, McLeod R. Cong H, et al. Among authors: alexander j. Immunome Res. 2010 Dec 3;6:12. doi: 10.1186/1745-7580-6-12. Immunome Res. 2010. PMID: 21129215 Free PMC article.
Toxoplasma gondii HLA-B*0702-restricted GRA7(20-28) peptide with adjuvants and a universal helper T cell epitope elicits CD8(+) T cells producing interferon-γ and reduces parasite burden in HLA-B*0702 mice.
Cong H, Mui EJ, Witola WH, Sidney J, Alexander J, Sette A, Maewal A, El Bissati K, Zhou Y, Suzuki Y, Lee D, Woods S, Sommerville C, Henriquez FL, Roberts CW, McLeod R. Cong H, et al. Among authors: alexander j. Hum Immunol. 2012 Jan;73(1):1-10. doi: 10.1016/j.humimm.2011.10.006. Epub 2011 Oct 12. Hum Immunol. 2012. PMID: 22027386 Free PMC article.
6,054 results