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Enzyme-mediated depletion of methylthioadenosine restores T cell function in MTAP-deficient tumors and reverses immunotherapy resistance.
Gjuka D, Adib E, Garrison K, Chen J, Zhang Y, Li W, Boutz D, Lamb C, Tanno Y, Nassar A, El Zarif T, Kale N, Rakaee M, Mouhieddine TH, Alaiwi SA, Gusev A, Rogers T, Gao J, Georgiou G, Kwiatkowski DJ, Stone E. Gjuka D, et al. Among authors: boutz d. Cancer Cell. 2023 Oct 9;41(10):1774-1787.e9. doi: 10.1016/j.ccell.2023.09.005. Epub 2023 Sep 28. Cancer Cell. 2023. PMID: 37774699
Molecular Architecture of Early Dissemination and Massive Second Wave of the SARS-CoV-2 Virus in a Major Metropolitan Area.
Long SW, Olsen RJ, Christensen PA, Bernard DW, Davis JJ, Shukla M, Nguyen M, Saavedra MO, Yerramilli P, Pruitt L, Subedi S, Kuo HC, Hendrickson H, Eskandari G, Nguyen HAT, Long JH, Kumaraswami M, Goike J, Boutz D, Gollihar J, McLellan JS, Chou CW, Javanmardi K, Finkelstein IJ, Musser JM. Long SW, et al. Among authors: boutz d. mBio. 2020 Oct 30;11(6):e02707-20. doi: 10.1128/mBio.02707-20. mBio. 2020. PMID: 33127862 Free PMC article.
Panorama of ancient metazoan macromolecular complexes.
Wan C, Borgeson B, Phanse S, Tu F, Drew K, Clark G, Xiong X, Kagan O, Kwan J, Bezginov A, Chessman K, Pal S, Cromar G, Papoulas O, Ni Z, Boutz DR, Stoilova S, Havugimana PC, Guo X, Malty RH, Sarov M, Greenblatt J, Babu M, Derry WB, Tillier ER, Wallingford JB, Parkinson J, Marcotte EM, Emili A. Wan C, et al. Nature. 2015 Sep 17;525(7569):339-44. doi: 10.1038/nature14877. Epub 2015 Sep 7. Nature. 2015. PMID: 26344197 Free PMC article.
Proteomic identification of monoclonal antibodies from serum.
Boutz DR, Horton AP, Wine Y, Lavinder JJ, Georgiou G, Marcotte EM. Boutz DR, et al. Anal Chem. 2014 May 20;86(10):4758-66. doi: 10.1021/ac4037679. Epub 2014 May 1. Anal Chem. 2014. PMID: 24684310 Free PMC article.
Persistent Antibody Clonotypes Dominate the Serum Response to Influenza over Multiple Years and Repeated Vaccinations.
Lee J, Paparoditis P, Horton AP, Frühwirth A, McDaniel JR, Jung J, Boutz DR, Hussein DA, Tanno Y, Pappas L, Ippolito GC, Corti D, Lanzavecchia A, Georgiou G. Lee J, et al. Among authors: boutz dr. Cell Host Microbe. 2019 Mar 13;25(3):367-376.e5. doi: 10.1016/j.chom.2019.01.010. Epub 2019 Feb 19. Cell Host Microbe. 2019. PMID: 30795981 Free PMC article.
Influenza vaccination in the elderly boosts antibodies against conserved viral proteins and egg-produced glycans.
Jung J, Mundle ST, Ustyugova IV, Horton AP, Boutz DR, Pougatcheva S, Prabakaran P, McDaniel JR, King GR, Park D, Person MD, Ye C, Tan B, Tanno Y, Kim JE, Curtis NC, DiNapoli J, Delagrave S, Ross TM, Ippolito GC, Kleanthous H, Lee J, Georgiou G. Jung J, et al. Among authors: boutz dr. J Clin Invest. 2021 Jul 1;131(13):e148763. doi: 10.1172/JCI148763. J Clin Invest. 2021. PMID: 34196304 Free PMC article.
Identification and characterization of the constituent human serum antibodies elicited by vaccination.
Lavinder JJ, Wine Y, Giesecke C, Ippolito GC, Horton AP, Lungu OI, Hoi KH, DeKosky BJ, Murrin EM, Wirth MM, Ellington AD, Dörner T, Marcotte EM, Boutz DR, Georgiou G. Lavinder JJ, et al. Among authors: boutz dr. Proc Natl Acad Sci U S A. 2014 Feb 11;111(6):2259-64. doi: 10.1073/pnas.1317793111. Epub 2014 Jan 27. Proc Natl Acad Sci U S A. 2014. PMID: 24469811 Free PMC article.
Sera Antibody Repertoire Analyses Reveal Mechanisms of Broad and Pandemic Strain Neutralizing Responses after Human Norovirus Vaccination.
Lindesmith LC, McDaniel JR, Changela A, Verardi R, Kerr SA, Costantini V, Brewer-Jensen PD, Mallory ML, Voss WN, Boutz DR, Blazeck JJ, Ippolito GC, Vinje J, Kwong PD, Georgiou G, Baric RS. Lindesmith LC, et al. Among authors: boutz dr. Immunity. 2019 Jun 18;50(6):1530-1541.e8. doi: 10.1016/j.immuni.2019.05.007. Immunity. 2019. PMID: 31216462 Free PMC article.
Prevalent, protective, and convergent IgG recognition of SARS-CoV-2 non-RBD spike epitopes.
Voss WN, Hou YJ, Johnson NV, Delidakis G, Kim JE, Javanmardi K, Horton AP, Bartzoka F, Paresi CJ, Tanno Y, Chou CW, Abbasi SA, Pickens W, George K, Boutz DR, Towers DM, McDaniel JR, Billick D, Goike J, Rowe L, Batra D, Pohl J, Lee J, Gangappa S, Sambhara S, Gadush M, Wang N, Person MD, Iverson BL, Gollihar JD, Dye JM, Herbert AS, Finkelstein IJ, Baric RS, McLellan JS, Georgiou G, Lavinder JJ, Ippolito GC. Voss WN, et al. Among authors: boutz dr. Science. 2021 Jun 4;372(6546):1108-1112. doi: 10.1126/science.abg5268. Epub 2021 May 4. Science. 2021. PMID: 33947773 Free PMC article.
44 results