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Antibodies targeting a quaternary site on SARS-CoV-2 spike glycoprotein prevent viral receptor engagement by conformational locking.
Liu L, Casner RG, Guo Y, Wang Q, Iketani S, Chan JF, Yu J, Dadonaite B, Nair MS, Mohri H, Reddem ER, Yuan S, Poon VK, Chan CC, Yuen KY, Sheng Z, Huang Y, Bloom JD, Shapiro L, Ho DD. Liu L, et al. Among authors: yuen ky. Immunity. 2023 Oct 10;56(10):2442-2455.e8. doi: 10.1016/j.immuni.2023.09.003. Epub 2023 Sep 29. Immunity. 2023. PMID: 37776849 Free PMC article.
Recombinant modified vaccinia virus Ankara expressing the spike glycoprotein of severe acute respiratory syndrome coronavirus induces protective neutralizing antibodies primarily targeting the receptor binding region.
Chen Z, Zhang L, Qin C, Ba L, Yi CE, Zhang F, Wei Q, He T, Yu W, Yu J, Gao H, Tu X, Gettie A, Farzan M, Yuen KY, Ho DD. Chen Z, et al. Among authors: yuen ky. J Virol. 2005 Mar;79(5):2678-88. doi: 10.1128/JVI.79.5.2678-2688.2005. J Virol. 2005. PMID: 15708987 Free PMC article.
SARS coronavirus spike polypeptide DNA vaccine priming with recombinant spike polypeptide from Escherichia coli as booster induces high titer of neutralizing antibody against SARS coronavirus.
Woo PC, Lau SK, Tsoi HW, Chen ZW, Wong BH, Zhang L, Chan JK, Wong LP, He W, Ma C, Chan KH, Ho DD, Yuen KY. Woo PC, et al. Among authors: yuen ky. Vaccine. 2005 Oct 10;23(42):4959-68. doi: 10.1016/j.vaccine.2005.05.023. Vaccine. 2005. PMID: 15993989 Free PMC article.
Intranasal vaccination of recombinant adeno-associated virus encoding receptor-binding domain of severe acute respiratory syndrome coronavirus (SARS-CoV) spike protein induces strong mucosal immune responses and provides long-term protection against SARS-CoV infection.
Du L, Zhao G, Lin Y, Sui H, Chan C, Ma S, He Y, Jiang S, Wu C, Yuen KY, Jin DY, Zhou Y, Zheng BJ. Du L, et al. Among authors: yuen ky. J Immunol. 2008 Jan 15;180(2):948-56. doi: 10.4049/jimmunol.180.2.948. J Immunol. 2008. PMID: 18178835 Free PMC article.
Studies of SARS virus vaccines.
Zheng BJ, Du LY, Zhao GY, Lin YP, Sui HY, Chan C, Ma S, Guan Y, Yuen KY. Zheng BJ, et al. Among authors: yuen ky. Hong Kong Med J. 2008 Aug;14 Suppl 4:39-43. Hong Kong Med J. 2008. PMID: 18708674 Free article. Review.
Disseminated penicilliosis, recurrent bacteremic nontyphoidal salmonellosis, and burkholderiosis associated with acquired immunodeficiency due to autoantibody against gamma interferon.
Tang BS, Chan JF, Chen M, Tsang OT, Mok MY, Lai RW, Lee R, Que TL, Tse H, Li IW, To KK, Cheng VC, Chan EY, Zheng B, Yuen KY. Tang BS, et al. Among authors: yuen ky. Clin Vaccine Immunol. 2010 Jul;17(7):1132-8. doi: 10.1128/CVI.00053-10. Epub 2010 May 5. Clin Vaccine Immunol. 2010. PMID: 20445006 Free PMC article.
1,298 results