Hecht F - Search Results

1

Estimating the contribution of CD4 T cell subset proliferation and differentiation to HIV persistence.

Reeves DB, Bacchus-Souffan C, Fitch M, Abdel-Mohsen M, Hoh R, Ahn H, Stone M, Hecht F, Martin J, Deeks SG, Hellerstein MK, McCune JM, Schiffer JT, Hunt PW. Reeves DB, et al. Among authors: hecht f. Nat Commun. 2023 Oct 2;14(1):6145. doi: 10.1038/s41467-023-41521-1. Nat Commun. 2023. PMID: 37783718 Free PMC article.

2

Cell-based measures of viral persistence are associated with immune activation and programmed cell death protein 1 (PD-1)-expressing CD4+ T cells.

Hatano H, Jain V, Hunt PW, Lee TH, Sinclair E, Do TD, Hoh R, Martin JN, McCune JM, Hecht F, Busch MP, Deeks SG. Hatano H, et al. Among authors: hecht f. J Infect Dis. 2013 Jul;208(1):50-6. doi: 10.1093/infdis/jis630. Epub 2012 Oct 22. J Infect Dis. 2013. PMID: 23089590 Free PMC article.

3

PD-1 blockade potentiates HIV latency reversal ex vivo in CD4⁺ T cells from ART-suppressed individuals.

Fromentin R, DaFonseca S, Costiniuk CT, El-Far M, Procopio FA, Hecht FM, Hoh R, Deeks SG, Hazuda DJ, Lewin SR, Routy JP, Sékaly RP, Chomont N. Fromentin R, et al. Nat Commun. 2019 Feb 18;10(1):814. doi: 10.1038/s41467-019-08798-7. Nat Commun. 2019. PMID: 30778080 Free PMC article.

4

Longitudinal study reveals HIV-1-infected CD4+ T cell dynamics during long-term antiretroviral therapy.

Antar AA, Jenike KM, Jang S, Rigau DN, Reeves DB, Hoh R, Krone MR, Keruly JC, Moore RD, Schiffer JT, Nonyane BA, Hecht FM, Deeks SG, Siliciano JD, Ho YC, Siliciano RF. Antar AA, et al. Among authors: hecht fm. J Clin Invest. 2020 Jul 1;130(7):3543-3559. doi: 10.1172/JCI135953. J Clin Invest. 2020. PMID: 32191639 Free PMC article. Clinical Trial.

5

Relationship between CD4 T cell turnover, cellular differentiation and HIV persistence during ART.

Bacchus-Souffan C, Fitch M, Symons J, Abdel-Mohsen M, Reeves DB, Hoh R, Stone M, Hiatt J, Kim P, Chopra A, Ahn H, York VA, Cameron DL, Hecht FM, Martin JN, Yukl SA, Mallal S, Cameron PU, Deeks SG, Schiffer JT, Lewin SR, Hellerstein MK, McCune JM, Hunt PW. Bacchus-Souffan C, et al. PLoS Pathog. 2021 Jan 19;17(1):e1009214. doi: 10.1371/journal.ppat.1009214. eCollection 2021 Jan. PLoS Pathog. 2021. PMID: 33465157 Free PMC article.

6

HIV-1 Genomes Are Enriched in Memory CD4⁺ T-Cells with Short Half-Lives.

Morcilla V, Bacchus-Souffan C, Fisher K, Horsburgh BA, Hiener B, Wang XQ, Schlub TE, Fitch M, Hoh R, Hecht FM, Martin JN, Deeks SG, Hellerstein MK, McCune JM, Hunt PW, Palmer S. Morcilla V, et al. mBio. 2021 Oct 26;12(5):e0244721. doi: 10.1128/mBio.02447-21. Epub 2021 Sep 21. mBio. 2021. PMID: 34544282 Free PMC article.

7

Immune activation set point during early HIV infection predicts subsequent CD4+ T-cell changes independent of viral load.

Deeks SG, Kitchen CM, Liu L, Guo H, Gascon R, Narváez AB, Hunt P, Martin JN, Kahn JO, Levy J, McGrath MS, Hecht FM. Deeks SG, et al. Blood. 2004 Aug 15;104(4):942-7. doi: 10.1182/blood-2003-09-3333. Epub 2004 Apr 29. Blood. 2004. PMID: 15117761 Free article.

8

Cytomegalovirus-specific T cells persist at very high levels during long-term antiretroviral treatment of HIV disease.

Naeger DM, Martin JN, Sinclair E, Hunt PW, Bangsberg DR, Hecht F, Hsue P, McCune JM, Deeks SG. Naeger DM, et al. Among authors: hecht f. PLoS One. 2010 Jan 29;5(1):e8886. doi: 10.1371/journal.pone.0008886. PLoS One. 2010. PMID: 20126452 Free PMC article.

9

Tryptophan catabolism by indoleamine 2,3-dioxygenase 1 alters the balance of TH17 to regulatory T cells in HIV disease.

Favre D, Mold J, Hunt PW, Kanwar B, Loke P, Seu L, Barbour JD, Lowe MM, Jayawardene A, Aweeka F, Huang Y, Douek DC, Brenchley JM, Martin JN, Hecht FM, Deeks SG, McCune JM. Favre D, et al. Among authors: hecht fm. Sci Transl Med. 2010 May 19;2(32):32ra36. doi: 10.1126/scitranslmed.3000632. Sci Transl Med. 2010. PMID: 20484731 Free PMC article.

10

Initiation of antiretroviral therapy at higher nadir CD4+ T-cell counts is associated with reduced arterial stiffness in HIV-infected individuals.

Ho JE, Deeks SG, Hecht FM, Xie Y, Schnell A, Martin JN, Ganz P, Hsue PY. Ho JE, et al. AIDS. 2010 Jul 31;24(12):1897-905. doi: 10.1097/QAD.0b013e32833bee44. AIDS. 2010. PMID: 20543654 Free PMC article.

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