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Page 1
Control of Cell Death in Health and Disease.
Kayagaki N, Webster JD, Newton K. Kayagaki N, et al. Among authors: newton k. Annu Rev Pathol. 2024 Jan 24;19:157-180. doi: 10.1146/annurev-pathmechdis-051022-014433. Epub 2023 Oct 3. Annu Rev Pathol. 2024. PMID: 37788577 Free article. Review.
Absent in melanoma 2 is required for innate immune recognition of Francisella tularensis.
Jones JW, Kayagaki N, Broz P, Henry T, Newton K, O'Rourke K, Chan S, Dong J, Qu Y, Roose-Girma M, Dixit VM, Monack DM. Jones JW, et al. Among authors: newton k. Proc Natl Acad Sci U S A. 2010 May 25;107(21):9771-6. doi: 10.1073/pnas.1003738107. Epub 2010 May 10. Proc Natl Acad Sci U S A. 2010. PMID: 20457908 Free PMC article.
Non-canonical inflammasome activation targets caspase-11.
Kayagaki N, Warming S, Lamkanfi M, Vande Walle L, Louie S, Dong J, Newton K, Qu Y, Liu J, Heldens S, Zhang J, Lee WP, Roose-Girma M, Dixit VM. Kayagaki N, et al. Among authors: newton k. Nature. 2011 Oct 16;479(7371):117-21. doi: 10.1038/nature10558. Nature. 2011. PMID: 22002608
Phosphorylation of NLRC4 is critical for inflammasome activation.
Qu Y, Misaghi S, Izrael-Tomasevic A, Newton K, Gilmour LL, Lamkanfi M, Louie S, Kayagaki N, Liu J, Kömüves L, Cupp JE, Arnott D, Monack D, Dixit VM. Qu Y, et al. Among authors: newton k. Nature. 2012 Oct 25;490(7421):539-42. doi: 10.1038/nature11429. Epub 2012 Aug 12. Nature. 2012. PMID: 22885697
Deubiquitinase DUBA is a post-translational brake on interleukin-17 production in T cells.
Rutz S, Kayagaki N, Phung QT, Eidenschenk C, Noubade R, Wang X, Lesch J, Lu R, Newton K, Huang OW, Cochran AG, Vasser M, Fauber BP, DeVoss J, Webster J, Diehl L, Modrusan Z, Kirkpatrick DS, Lill JR, Ouyang W, Dixit VM. Rutz S, et al. Among authors: newton k. Nature. 2015 Feb 19;518(7539):417-21. doi: 10.1038/nature13979. Epub 2014 Dec 3. Nature. 2015. PMID: 25470037
β-Cell Insulin Secretion Requires the Ubiquitin Ligase COP1.
Suriben R, Kaihara KA, Paolino M, Reichelt M, Kummerfeld SK, Modrusan Z, Dugger DL, Newton K, Sagolla M, Webster JD, Liu J, Hebrok M, Dixit VM. Suriben R, et al. Among authors: newton k. Cell. 2015 Dec 3;163(6):1457-67. doi: 10.1016/j.cell.2015.10.076. Epub 2015 Nov 25. Cell. 2015. PMID: 26627735 Free article.
Necroptosis and Inflammation.
Newton K, Manning G. Newton K, et al. Annu Rev Biochem. 2016 Jun 2;85:743-63. doi: 10.1146/annurev-biochem-060815-014830. Epub 2016 Feb 8. Annu Rev Biochem. 2016. PMID: 26865533 Review.
RIPK3 deficiency or catalytically inactive RIPK1 provides greater benefit than MLKL deficiency in mouse models of inflammation and tissue injury.
Newton K, Dugger DL, Maltzman A, Greve JM, Hedehus M, Martin-McNulty B, Carano RA, Cao TC, van Bruggen N, Bernstein L, Lee WP, Wu X, DeVoss J, Zhang J, Jeet S, Peng I, McKenzie BS, Roose-Girma M, Caplazi P, Diehl L, Webster JD, Vucic D. Newton K, et al. Cell Death Differ. 2016 Sep 1;23(9):1565-76. doi: 10.1038/cdd.2016.46. Epub 2016 May 13. Cell Death Differ. 2016. PMID: 27177019 Free PMC article.
704 results