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SGN-B7H4V, an investigational vedotin ADC directed to the immune checkpoint ligand B7-H4, shows promising activity in preclinical models.
J Immunother Cancer. 2023 Oct;11(10):e007572. doi: 10.1136/jitc-2023-007572.
J Immunother Cancer. 2023.
PMID: 37793853
Free PMC article.
The origins of cellular life.
Schrum JP, Zhu TF, Szostak JW.
Schrum JP, et al.
Cold Spring Harb Perspect Biol. 2010 Sep;2(9):a002212. doi: 10.1101/cshperspect.a002212. Epub 2010 May 19.
Cold Spring Harb Perspect Biol. 2010.
PMID: 20484387
Free PMC article.
Review.
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Efficient and rapid template-directed nucleic acid copying using 2'-amino-2',3'-dideoxyribonucleoside-5'-phosphorimidazolide monomers.
Schrum JP, Ricardo A, Krishnamurthy M, Blain JC, Szostak JW.
Schrum JP, et al.
J Am Chem Soc. 2009 Oct 14;131(40):14560-70. doi: 10.1021/ja906557v.
J Am Chem Soc. 2009.
PMID: 19757789
Free PMC article.
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Template-directed synthesis of a genetic polymer in a model protocell.
Mansy SS, Schrum JP, Krishnamurthy M, Tobé S, Treco DA, Szostak JW.
Mansy SS, et al. Among authors: schrum jp.
Nature. 2008 Jul 3;454(7200):122-5. doi: 10.1038/nature07018. Epub 2008 Jun 4.
Nature. 2008.
PMID: 18528332
Free PMC article.
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The AID antibody diversification enzyme is regulated by protein kinase A phosphorylation.
Basu U, Chaudhuri J, Alpert C, Dutt S, Ranganath S, Li G, Schrum JP, Manis JP, Alt FW.
Basu U, et al. Among authors: schrum jp.
Nature. 2005 Nov 24;438(7067):508-11. doi: 10.1038/nature04255. Epub 2005 Oct 26.
Nature. 2005.
PMID: 16251902
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